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Dr. Linda Liau: Brain cancer vaccine pioneer,
Your photographs are stunning. What a talent you have.
well said.
Remember the old saying, 'if you can't stand the heat, get out of the kitchen'
Always enjoy your posts but I think this statement is OTT. Hopefully made out of extreme frustration - which I and many others here share
well put together. As you said, the quality of FUD now being posted is almost embarrasingly dreadful
LP trying to gold plate TLD but first she has to gold plate her house, hence the secrecy
now that is sound advice!
sorry Bio, that was meant for Sojo. I then replied to myself. I think another whiskey is in order
Ah! Sojo just posted the predictions while my message was in transit. Thanks Sojo
I'd be very interested in what you think the SP will be in 8 days time! I am owed a 4 figure sum and it has been promised to me on wednesday next week. I am going to top up my NWBO stock. :)
What a complete load of nonsense.
Around 9 months to 1 year is not unusua
A few years ago, I submitted a manuscript to a medical journal and was asked to make some small revisions by the reviewers. We made the amendments quickly and the paper was accepted for publication within 5 weeks of submission. It appeared as an early on-line paper on the journal's website 8 weeks later.
The process can be fairly rapid if the story is good and the journal wants to publish.
I very much agree with you Gary. Having worked in cancer research for over 30 years, I have seen some positive steps in treating a variety of tumor types and it is clear to me that it will take a multi-pronged approach to see further improvements in cancers across the board.
It is also the case that cancer will never be eliminated. We will learn to manage these diseases (as we have with CML) and with the increasing knowledge we are gaining about the underlying genetics of cancer sub-types and what factors trigger uncontrolled cell growth, I believe we will make huge leaps towards a far better outcome for patients with cancer.
Personalised approaches such as the use of tumor-infiltrating lymphocytes, CAR-T and DCVax-L +/- other therapeutic agents will form part of the journey in improving treatments.
The only question that matters right now is why are they refusing to release the data?
the question will become how long have they known it was this bad?
I agree
This has been the most impressive treatment development in cancer in the last 50 yrs. 5 yr survival in the early 1990s was about 30%. Now, patients with CML have the same or almost the same life expectancy as the general population.
Wouldn't it be wonderful to be able to talk about DCVax as being a similar game changer in GBM
That is how medical treatment progresses. A good example is in chronic myeloid leukaemia - Gary will be very familiar. The introduction of tyrosine kinase inhibitors has completely changed patient outcome.
Any future therapies in CML will have to show an improvement over TKI and not the previous treatments
Excellent post. This is truly disruptive technology and, as such, is at great risk of attack by those BP that are financially comfortable with the status quo or those who have bet against the success of this treatment.
Patients with this devastating cancer will benefit hugely from DCVax-L (and DCVax-D) so it is crucial that NWBO do not leave themselves open to any attack.
Validation of the data derived from the P3 trial by clinicians via a peer-reviewed publication (preferably in a leading high-impact factor journal) is essential to prevent the deluge of attacks that will inevitably come after TLD. NWBO is absolutely correct to be following this route although it will of course be Drs Liau, Ashkan et al who will write the manuscript.
It's obvious. It's a slow warrant maneuver not to ring alarms, it's warrant dumping without a quick drop back to .14
ae_kuster I think everyone is DONE with You
Do they list the number of dead GBM patients hoping for a miracle while they drag this cure out a few more years trying to mine the hell out of the data from this dumpster fire?
I just cannot see LP selling the company until DCVax-L is approved for patients
I agree with this.
The SP at the moment is largely irrelevant to those of us who believe in the science. There may be bear raids, accumulation, nervous investors off-loading, but the data will undoubtedly (IMO) be positive. The SP will rise to the $3-6 range once TLD is announced.
What happens after that largely depends on the success or otherwise of RA approval and BLA. Probably needs a JV or BO to get this treatment to patients. When this occurs, SP should exceed $20 and more.
GLTL
I think you are being very disrespectful to those who bought over $2. It is neither a joke nor funny. What will be nice is for those investors who did pay over $2 to be in a position to sell their stock for $5, $10 or even $20 once we have TLD and a BLA in the future.
I do like your posts. You have an enviable gift for cutting right through the crap.
I find it hard to imagine that LP will sell out until DCVax-L is approved - early next year in UK IMHO
Thank you Sharpie
I don't suppose it is possible to remove the patients with IDH mutant GBM from the comparative historical trials as this data would likely not be known?
"NWBO is like an Italian plumber, they will be there someday and will fix it lastminute..."
Hold on a bit Anders! My Father is an Italian plumber.
Come to think of it, I have not seen him for months, and he owes me 50 EURO
Why on earth would they do that? Those of us who believe in the science and are confident in the data being positive will hold (ok, not often patiently) for significant gains. Those who don't should sell up and find another company in which to invest.
Wow! Thank you for passing on this important news. I feel much more informed now. I'd better sell up quickly and take my 850% profits. I assume you have sold everything also?
Another hand in the air from me for September-November. Everything seems to point to this period. And I believe the results will be very good for us longs. Just wish I could afford to buy more stock :(
It states "The early findings were published yesterday (29 May) in the Journal of Translational Medicine."
Must have been 30 May 2018
I very much appreciate your regular updates
well said Anders. Beyond my understanding!
Tremendous news Thermo. Long may his good health continue.
I heard a contestant on a UK radio quiz a couple of weeks ago say she had seen Bruce Springsteen in concert 56 times. Pretty impressive!
Ooops! I meant to put $0.14 not $0.17. Either way, sitting on a nice profit
$0.17 to $1.55 is an increase of over 1000%. Math not your strong point.