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Mikesc

12/08/22 6:52 PM

#390796 RE: crescentmotor #390791

Anavex has never not done well in a trial and we know that BP has a lot to lose if Anavex succeeds. This is all about a small bio changing the paradigm and it will not happen over night. Hang in there the science will prevail. As far as the Fu#d#sters are concerned... POUND SALT!

Kittykitty

12/08/22 6:59 PM

#390799 RE: crescentmotor #390791

Yes, I realize that this is a perilous situation and I may end up with a total loss, but I also understand the reasons for not responding more yet. He must get everything right at this point. It feels terrible to be out in the cold and perhaps this is a bad sign, but it cannot be known yet. I am not only concerned about feeling betrayed in the financial sense, but also for feeling that I was fighting for good. I will feel quite bad if this turns out poorly. In the meantime, I do not see a reason to lose faith. The research design and stat criticisms do not make much sense to me given my background. How anyone could think they could calculate the actual results and validity of this study based on such limited information (slides) is beyond me. Were approximations methods used for empty cells?, etc. The accusations that he, Missling, is hiding something because he has not given more information is also perplexing to me given how long it took me to enter data into stat software when I was doing research. And more importantly, hoping that there is actually a true treatment for neurodegenerative disorders given the tremendous suffering.

boi568

12/08/22 7:05 PM

#390801 RE: crescentmotor #390791

The suggestion is that Anavex misstated the results of its trial. Unfortunately, sometimes a company will do that, but certainly not in the manner being discussed here.

In this case, a misstatement would not be backed up by data released a few short weeks later. What's the point of cheating if you have no chance of getting away with it for any length of time?

The way a crooked company cheats is to cook its books or fake its lab data; you can hope to get away with that for quite a while, long enough to benefit from it. That's not what we are facing with the CTAD accusation, which is the use of an inappropriate ADCS-ADL endpoint descriptor on a non-optimal data set.

Missling has no history of misbehavior. He certainly survived the 2015 short's mudslinging unscathed. He has received validation in this case from several third party experts. Missling has shown no signs of being capable of risking his career and his liberty over 15 minutes of slides in San Francisco.

So these innuendos are far from persuasive for me.