Replies to post #291992 on NorthWest Biotherapeutics Inc (NWBO)

[longfellow95]

DISAGREE :If topline is negative , stock is zero within 60 seconds of that PR.Bankruptcy filed within 24 hours.55 lawsuits filed within 48 hours.No way insiders could get their debts repaid.His $250,000 covert is a binary, all or none, investment.Wallpaper for his retirement home if topline does not earn FDA commercial sales approval.

What makes you think topline announcement has to be a binary event?

[hyperopia]

Uh no, topline WILL NOT be negative. Normally, a topline announcement is simply a brief statement whether the trial met its primary or secondary endpoints with statistical significance or not, then further data and analysis is presented in a peer-reviewed journal or conference a month or more later. That Northwest Bio intends to spend a few weeks with the full data and their SAB before even making any such announcement, indicates that they intend to be fully in control of the narrative. At a minimum, there will certainly be positive data (pre-selected MGMT Methylation Status) from the trial, which will be emphasized. Even if an endpoint did not reach statistical significance, the headline could still read something like” Northwest Biotherapeutics Announces Positive Survival Data From Phase III Trial of DCVax-L.”

And ae, just to be clear, I think that is the worst-case scenario. I actually think the survival data will be unprecedented and will be a major advance in cancer treatment, with milestone survival triple or quadruple historical comparisons.