Replies to post #292164 on NorthWest Biotherapeutics Inc (NWBO)

[hankmanhub]

Hope not. If they omit the statistical significance on the endpoints, that will be the kiss of death. Everyone will assume the worst for the reason they left this data out as it is usually provided (if positive).

[longfellow95]

Uh no, topline WILL NOT be negative. Normally, a topline announcement is simply a brief statement whether the trial met its primary or secondary endpoints with statistical significance or not, then further data and analysis is presented in a peer-reviewed journal or conference a month or more later. That Northwest Bio intends to spend a few weeks with the full data and their SAB before even making any such announcement, indicates that they intend to be fully in control of the narrative. At a minimum, there will certainly be positive data (pre-selected MGMT Methylation Status) from the trial, which will be emphasized. Even if an endpoint did not reach statistical significance, the headline could still read something like” Northwest Biotherapeutics Announces Positive Survival Data From Phase III Trial of DCVax-L.”

Agree with this being what we might see.

[biosectinvestor]

Agreed and well said! I think, and assuming it meets our expectations, it will be perceived as a major advance in immune therapies for cancer.