Replies to post #112842 on Amarin Corp Plc (AMRN)

[rafunrafun]

I find it amusing that after Ralphie said earlier this week that he doesn't think that vascepa is effective, he STILL hasn't been able to provide any substantive reasoning to defend his point of view.

One failed attempt at such was a story about his 'patient' whose TG dropped and then came back to where it was originally (and that is based on ONE BLOOD TEST). This, ladies and gentlemen, is proof that vascepa does not work - and now onto search for Bigfoot.

But here is the kicker, he ALSO writes that in his 'experience', vascepa reduces TG by approximately 25%, on average. This is where common sense should kick in.... If you believe about the 25% reduction, doesn't that mean that one guy from the example above is an outlier?! So what the heck is the purpose of writing about this ONE outlier? Why not write about the average of the so-called 300 patients and the 25% reduction of TG?

I don't mind opposing viewpoints. I actually welcome them because they may help me to rethink about my investment. But this is absolute nonsense. No substance whatsoever.

Put up a well-reasoned argument. Defend your position with logic and substance, and not empty rhetoric and fear-mongering.

To summarize why vascepa doesn't work:

-out of 300 patience prescribed it, their average TG reduction is 25%

-this one guy's TG went back to where it was originally, via 1 Test

-the end.

[Whalatane]

Ralphey ...re fasting / non fasting from the NY times

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Fasting may provide a more accurate assessment of triglyceride levels, another measure of heart risk. But “it doesn’t matter if you eat” before a cholesterol test if the main goal is to evaluate LDL and HDL cholesterol levels, said Dr. Mary Norine Walsh, the president-elect of the American College of Cardiology.

“One of the barriers to getting cholesterol testing done is that patients arrive at the doctor’s office not fasting, and then it doesn’t get done,” Dr. Walsh said. She runs the test even if patients have eaten before an appointment and encourages other doctors to do the same.

Among the studies that found that fasting may have little impact on cholesterol blood test results was a large 2012 Canadian study of more than 200,000 people that found average levels for HDL and total cholesterol varied less than 2 percent, regardless of whether people had eaten an hour earlier or fasted for 16 hours. LDL cholesterol levels varied by less than 10 percent whether patients had fasted or not, and triglyceride levels varied by less than 20 percent, that study found.


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TG levels seem to be the most affected by whether patient fasts properly or not.

In an earlier post I listed my TG values . You may have thought they are all fine . Problem is my HDL has never been over 40 ...usually low 30's ...and my cardiologist was concerned ( as you are ) about the HDL / TG ratio....Family history of heart attacks , mixed D , Hetero FH etc

Also ...you refer to OTC Omega 3's .....believe OTC is the wrong label ...they are all DS ( dietary supplements ) .

Kiwi