Anavex Life Sciences Corp (AVXL)

[falconer66a]

Shape ain’t right for toxicity.

This [the molecule’s unique molecular structure] may explain why blarcamasine seems to have no side effects: It is suited to interact with a target that has a unique structure, and the inference would be that blarcamasine cannot interact with other proteins because they are too different in kind from the S1R.

Boi, thanks. Perfectly stated.

That’s it. Blarcamesine simply doesn’t stick or bind to anything else in the cell, other than the sigma-1 receptor protein, where it activates a diversity of propitious “downstream” biochemical outcomes; therefore can’t pathogenically disrupt anything. Toxicologically, it’s inert. Pretty nifty for a drug working in the nervous system.

And, you are right about Anavex 3-71. It will prove even less toxic, and far more potent, acting in microgram, not milligram dosages.