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I’m very sorry to impact your estate plans, however Jon just recently (late 2021 I think) sold his beautiful French chateau style house on the River to live out in the Hamptons where he and his son have a vineyard/wine business.
He might very well have another crash pad place in NJ, however I love the residence he sold and often pass it on my ice cream and quiche runs in Rumson. (Nwbo coming in too late for me to buy the beautiful estate for myself)
Jon started his Soul Kitchen concept in Red Bank, and more of them have been opened, to give back to society, as places (eating establishments) based on volunteering and providing meals to everyone, where those less able to afford meals eat free and can volunteer to contribute back, while those who can afford it may pay and volunteer.
It says a lot about JBJ that he volunteers, including washing dishes and other chores you might expect a rock superstar might be too upity to do willingly, but not JBJ.
When our boys were young, at a Red Bank antique car and street event, he brought his young son and was just blending in among the anonymous crowd wearing a western hat, and I was sitting outside at the local coffee/food shop with my son, when I noticed him and our eyes connected from a distance.
We gave each other a silent and discrete acknowledgement with a slight nod, more like two dads, and I assure you he didn’t know me. (Although my daughter had one of his children in an extracurricular art class she had volunteered to assist.)
JBJ is good people as far as I’m concerned and you could do a lot worse than support his social causes like the Soul Kitchens in your legacy planning!
That sounds like a nice problem to have, of being wealthy while you’re young!
Many of us more mature posters would trade a small to large fortune to be young again
We’ll all find a way to cope with our new nwbo wealth, and DCVax will also provide a positive return on our longevities, God willing!
I’m roughly half in Roth and half in brokerage, so if we get a buyout I’d be rooting for all stock no cash, in order to defer the taxes on the brokerage shares and hold the max number of the acquirer’s shares.
A BO for stock from a Merck or BMS, for example, would be a fairly safe and dependable equity paying a healthy and likely growing dividend stream.
1 Merck share for every 4 or 5 nwbo shares ($20-$25/share) would float my boat!
Of course a higher BO would always be welcome
Never count a good horse out!
You may remember a number of years back, maybe 6-10 years ago, when the various attacks appeared to be coordinated.
You had negative AF pieces, multiple frivolous lawsuits including searches for class action suit lead plaintiffs, heavy shorting, etc.
Kinda like this past May 10 NYAS, only worse since it was a prolonged attack at a more vulnerable time.
In fact I think it was this near BK experience that spawned the radio silence strategy strategy !
There’s always Gucci life vests and water wings
That would make for a very nice package, presentation and peer reviewed JA to provide the details!
Who or what is Big Daddy Mac?
Starting to feel like a Rocky movie, where the underdog, nwbo, has been diligently doing all the fundamental preparatory work leading up to the big event!
Cue the inspirational music (Feeling strong now… won’t be long now…..)
In this corner, the challenger from Bethesda Maryland, weighing in at 12 employees, the T cell tornado, the dendritic cell dynamo, the autologous vaccine vigilantes, nwbo!!!
Yo Linda! Lindaaaaa!
While y’all are in London Town maybe you can interest Sir Andrew Loyd Weber in writing and producing the DCVax/nwbo play, The Phantom of the Biotechs!
In the words of Stanley Tucci to Cher in Burlesque, “There you are! I thought we lost you for a minute”
Cognate’s Memphis location was planned for DCVax because it is located at a major air shipping hub and centrally located, the combination being very good for DCVax North American service area
I understand and AF used to be employed by the same commentator.
The guy used to run a hedge fund and the questionable behaviors were from back then, maybe 20 years ago?
Maybe I’m a softy however I think he is a better person today and much more principled in my opinion.
Boooyaaaahhhh!!!!!!!!
It’s unbelievably fantastic results the likes of which could only be dreamed of prior to the combo treatments!!!
I’m so happy for all the patients that will be given real hope and years of survival benefits!
The era of the three amigos, the Vega, the Pinto, and the AMC Gremlin!
Not the auto world’s greatest works
I should say that I remember Cognate being on the patent application but CRL bought Cognate and should have “inherited” their participation in the patent.
Just to make sure I’m remembering correctly it would be good to get corroboration from Flipper, who had been following the new patent applications.
Flipper are you there? TIA
CRL is a co-inventor on the DCVax iclc pd1 il2 combo patent, and not Merck, fwiw.
I believe this combination is what they’re seeking patent on, ucla/nwbo/cognate/IL-2 drug company (the co-inventors are each from these 4 companies) are co-inventors if memory serves me.
I’m sure Flipper knows about this combo patent because I think Flipper first shared a link to the patent application.
Note to self - for screen play include a scene with the LP character being asked to produce an annual meeting, to which the LP actor defiantly says back:
Annual meetings! We don’t need no stinking annual meetings!
Additional note - consider changing movie title to The Treasure of the Bethesda Maryland
The government, LP, and LL/UCLA should all go after the perpetrator of such an obvious false smear piece!
Possibly a Wilber gone mad, otherwise no one would!
That’s a good suggestion because I’m a fan of the blues, and a particular song I like is Stormy Monday by T-Bone Walker !!!
When I think of horse and meat, I think of the Italian deli meat mortadella, because in Italy it was available made from horse meat in addition to the pork variety sold in the USA. They say horse meat is sweet, but I think of Trigger, Black Beauty, and Mr. Ed, and stick with pork
As for me, maybe go from horseb4cart to Maybachmoonshot or Horseb4ferrari
Might I be so presumptuous to suggest Comfortable Man or It’s a Living Man
I’ve found for myself that reading the board intermittently instead of full time, plus taking a more chill attitude during the wait, helps.
Now however, I could use the comfort of a higher nwbo share price since I committed to new expenses that bring me close to my financial comfort zone as a retired person.
Otherwise if I was still working it would be easier to wait. I’ve already waited over a dozen years, so a callous has formed
All’s well that ends well, except for the lives and families that miss out for this hope in the meantime, like my mom and many, many other loved ones.
Look at the bright side, all the breadcrumb hunting and sleuthing, and trying to connect the dots and then evaluating all the negative narratives, is great for those of us that are getting up there in age to exercise our gray matter and help prevent dementia.
Only have kidding, maybe not kidding at all.
It’s also like attending a medical seminar one post at a time, and picking up interesting and not so interesting semi random facts!
In summary, reading this nwbo bulletin board is beneficial for knowledge and health, and the humor is good medicine too!
Good things come to those who wait
Based on my wait I best not get a lump of coal for Christmas this year!!
I wonder if either are available to join live or replay?
Scotty! Are you hinting at a shift in the script from talking down to talking up nwbo?
Truth! You can’t handle the truth!
Hooyaaahhhh!!!
The article mentions the two options going forward as DCVax and TTF, however TTF isn’t deemed cost effective by NICE according to how I read the article. DcvaxL hasn’t reached the point of NICE recommendation but should be upcoming and then hopefully approved in the UK, and then available under their health system and payments.
For this young man every month is so important and hence the crowdfunding approach to pay for DCVax under specials/compassionate means.
PM, I value your wisdom and feedback. I’ve learned it’s probably not best to post messages so soon after consuming a glass of red (Frappato Terre Siciliane) wine from my birth land. Maybe a little more than a glass.
The last thing I want is to appear insensitive to patients and families that have/are dealt with cancer. I’ve been through it personally.
There hasn’t been total quiet.
There have been PRs and ASCO industry theatre presentations and such, indicating important work and progress, and UK juvenile PIP acceptance…
There are none so blind as those who do not want to see…
Largely agree except that for some individuals their OS with DCVax qualifies as a cure for them, and any OS gain for any patients are days spent alive and maybe some hope of getting enhanced treatments in time.
No hope for the already passed on, and although I’ve seen goldfish flash frozen by liquid nitrogen and thawed out alive, I don’t think we’re close enough to thawing out humans alive (and without a mutha of a “freezer burn”
Agree 100% however the brain tumor research community and others are waiting for the peer reviewed JA, official full trial results, and other validation although I believe they unofficially acknowledge
I took the insufficient evidence of efficacy against the TTF device since the article stated DCVax ph3 trial results were still pending and thus the efficacy was to be established.
The title implies that the combination treatments of DCVax with the interleukin and PD1/PDL1 (keytruda) adjuvant, and the anecdotal comments regarding higher percentages of OS extended observations.
DCVax is the common component of the combo treatments and appears to play an SOC role in the combo research and trials!
Imo the odds are the presentation enhances the DCVax case.
You are rich in intellect and sensibilities, and besides, being middle class in Georgetown is like being rich in suburbia at large
As Hymen Roth said to Michael Corleone, you have your health, that’s the most important thing!
That reminds me; I was thinking whether you can attach a small tag to your wife’s clubs so you can set up proximity detection to alert you when they get within 15-20 feet of your bench (actually your cell phone so you can extend security around you wherever you go?