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Update on the article: http://citywire.co.uk/money/woodfords-new-biotech-could-be-the-next-amgen/a785925?ref=citywire-money-latest-news-list
(Update: this article has been amended to clarify that Northwest wants to be the leader in dendritic cell cancer vaccines not in the entire area of immune therapies.)
...Northwest is tackling neither of these. Its ambition is to lead a new field of 'dendritic' cancer vaccines. Its DCVax technology harnesses the dendritic or ‘master’ cells that organise the human body’s defence system.
Well, you have to understand one can be suspicious on message boards, regarding both neg or pos opinions when it holds on both extremes but also when the same leitmotiv is being brough over and over. But Eh! It's free speech! Of course sometimes, I (let's say I since I belong to that camp) can sound delusional with great expectations. .. if they weren't actually being more and more backed up with big glimpses of facts...
So for you having been invested for a few years, don't you agree that 2014 represents great steps in finalizing the base, the foundation of what could become... an empire? ;)
And real tangible reasults are getting pretty close now on both L and D and it's being backed up by the scientific field where Immunotherapy is hot and promising.
I understand your concerns about mgm and dilution... I don't have your experience and I might be naive... we'll see. But many here aren't naive at all!!!
My numbers:
Nov 21, 2015: 140$
Nov 21' 2016: 450$
Nov 21'2017: no idea
And for the believers out there, don't be discouraged by some honest, some dishonest and manipulative attemps to change your opinion.
You know how manipulation works, right... you try to look balanced, as if you were invested in NWBO for years, throw a few positives, and then bash, bash and bash again.
Well, I think the mgm wants to make NWBO a game changer; a paradigm in cancer treatments. I think L could become a soc in different grades of gliomas... in the entire Europe fist, and in US eventually. +Japan, Australia, Canada, India etc. I think L could have some value in treating other cancer types...
And... DIRECT? Well... if amazing news keep coming, are scientifically proven and real people get saved, well ya, you know...
This might be the best scenario, the opposite scenario of the past 20 posts out here tonight, but It might actually come truth.
So I am not too worried about dilution.
Enjoy your w-e
Talk to me about a vision, a plan; where a CEO knows exactly where DCVAX is heading... from 2010 interview.
'From everything we know about the biology, this same technology, this same product, the educated dendritic cells plus the whole set of antigens, the whole set of biomarkers from the tumor tissue, that should work on any cancer because all you’re doing is restoring the natural function, the natural power of the immune system that the tumor has been suppressing.”
This is so true:
From flipper44, Howard Wolinsky:
'As the saying goes, nothing is more powerful than an idea whose time has come. Yet, many proponents of new ideas have a ‘hard time' up until their colleagues become convinced of the merits. It is not only the reluctance of established research fields and communities that slow down the uptake of revolutionary hypotheses, but also a general reluctance to explore new ideas and support those who do so. As Pembrey commented, many more speculative ideas need to be considered, but scientific journals usually do not have the space for such conceptual papers. In addition, the main research funding organizations do not make ‘big bets' to support speculative research. “Funding bodies like the UK Medical Research Council encourage scientists to think out of the box,” Pembrey said. “But in the end these [applications] turn into minor projects.”
It is not only the reluctance of established research fields and communities that slow down the uptake of revolutionary hypotheses, but also a general reluctance to explore new ideas and support those who do so
Despite the difficulties, there is some comfort for those who think that they have a revolutionary insight that remains largely ignored: history has nearly always proven that, in the end, truth prevails, as the stories of great scientists such as Darwin, Heisenberg and Marshall show.'
Thanks sentiment! Actually I think it was about a week ago and not really about Nwbo but really about shorting and to understand more about it... I should find it, no worries. Thank you all for your time and devotion you put on your dd... it's harder for me since I'm french speaking and It's not my field at all... with my only one and only love stock and my work schedule; night, evening and day shifts on a roulette all the time.. I run after my sleep
Could I get again the link about a 'shorts' article that I sent to my gmail and lost it unfortunately, was it Evaluate, Flip or somebody else? Or I will make more research on I-Hub backwards. Thanks again. For someone who does not work in the Financial field, it was a very informative article about shorting.
ps. In my very short experience as an investor in the biotech world... I've never seen so much attemps to distort facts and harm a small biotech... also coming from the same person (remember.. b.a. in political sciences) so for me it just means we got something f'ing special here and never heard and done before.
Woot woot NWBO. What works for me, I don't sell shares. I add what I can afford.
Hum, did I miss anything? I think not. Dcvax-L is still saving and prolonging life of people, such as Direct, and a few catalysts are lined up. Cool then! Got to go, have to buy more shares, and go party tonight. I'm still 'in' for the wild and exotic party when we hit 300-400 pps. I shall miss the one around 100$. Till then, enjoy the roller coaster like I do :)
Since NWBO is listed on the DAX, I'm eager to see the impact over there. Great news, great performance from LP. Bravo!
p.s. How can Reuters make such a mistake on inoperable instead of operable...
I believe Staccani and BSB were expecting big and fast results on the technology and this is why they invested so much so quickly. The investor in this stock must be very patient. The big news that seems to be coming next week will be coming in 6 months. L and D are enormous as a technology. I think Linda is setting the table for everything L and D need to be a success story. It's just not now or tomorrow. EU takes time but once in place it's a huge market. I've been invested in NWBO since March 2013 and think I will see hundreds of pps once the DMC approves L early and through or at the end of Direct phase 2!
Wow you're really something
The first DCVAX-DIRECT patient treated by NWBIO was shown during a 2 min clip on National Geographic channel during S!2C and that's what you got to say? God bless our CEO Linda Powers. I know she doesn't do conference calls, so you have no clue on what's coming up and what's she's working on, besides H.E. So it creates frustration and anxiety. I have none bc I can hold on to my shares 12, 18 or 24 months if I have to. She's got her style and she got all of my trust. Today was a really nice surprise!
Jimmylee, you've been aroun since 2003... this seems like a lot of time and amazing in my vieww, feel free to share anything on this board, thanks
Good job! I had a copy too. We should post it once a week for the next 9 months...
Great article!!!
BSB, I think Les and Linda heard you ;) so you just have to add a 'few' more shares now great pr
BSB you invested that much bc you did your DD and this co met all your criteria. It would be unfortunate and just... crazy to pack it and leave. Trust your gut which was telling you that it was the best move you might have made in your lifetime. Don't be too impatient with pr's and pass your frustration with dumbells (in some precedent posts, I suggested walking dogs, hunting squirrels -not doing any harm to them of course, too cute... and sex! Rum can be nice also) Give it till January 1st, 2015. And you will owe me a beer :)
My gut, and my own dd, is telling me to trust Linda. (And I know I'm a complete novice in this field) But still, I do as much as with my mom who passed away 7 years ago. And in my field, actually, my gut is very reliable.
Besides, you have the chance to have the means. My objective was 10k shares and I'm well below that. Eventhough I'm squeezing 2 years of my life ending December of this year, for my investment which I bought in majority around 3,50$. I got the badluck and goodluck that my car got destroyed from a car that cought fire behind my, and I added to my position, in a taxable account. This is as much as I believe in our investment.
I just love it sentiment!
BSB... I can't answer your questions right now. But you know as well as I do that we'll sell some of our shares around 100's... and around 400's... and a bit in between. I took your advice and I'm still thinking about it... but never do I think we'll get something like this in our lifetime... I might be dreaming or I might be not. You know what? Lady Linda Powers... is telling me everything I need to know... you just need to read between the lines...
This is very tragic and I'm so sorry. Mrs Powers, I'm so sorry for your lost.
Afford, immunotherapy is hot and is rising as the most promising field in oncology for many years to come. NWBO is getting more and more attention as well. AF will fade soon, and The Streets and Cramer won't have the choice to get on the boat soon or they will lose a lot of credibility.
Reading your different posts, I think there's a consensus from Pyrrhonian, H2R, Sentiment and Bioinfo that LP is divulging sensitive info about what she can and is very careful about what she cannot or what could compromise the trial. So she got all our trust.
;) all of them
I also believe there will be more pr's on Direct, within a few weeks. The longer we wait, the stronger the pr will be, I think. I've always think we got a hell of an excellent strategist as a CEO, such as Sun Tzu was. She has all my confidence and everything she does or does not do yet is in all of our and her interest. I've never doubted that she saved a lot of people with compassionate use and by also offering the vaccine for whom it was made for, even though they have progressed; the pseudo progression sub-group. So, for some posters, bashing the CEO is not going to get you anywhere. You're not in her shoes, and I doubt you'd do a better job than she does. So breath in, breath out, have some tea, relax, do some yoga, lift some weights, have some sex if you can, watch the squirrels and wait.
I added 6k$ in the past week... soooooooooo happy!
'longtermthinker' I will quote you:
'If you believe in it, stick with it'. You're right.
Tell me, have you seen many CEO's who FIRST want to prolonge life of dying people, and cure a percentage of them. Linda Powers and Linda Liau might get a Nobel prize eventually. There is the business side, and the human side. She is great in both of those sides. We take this board seriously, because a lot of people are dying from gbm, prostate, ovarian cancer, and most inoperable cancers where patients are being told, well, sorry, you have x months to live. Best chance in another life. You know as much as I know that NWBO will save lots of people, and extend the life of so many. You clearly have an agenda. So, sorry, nope, no bashers have ever brought any concrete argument about the science. You guys attack whatever you can, in a total manipulation way, to keep the stock price as low as possible, to slow down this co and make it harder to finance. So, nope, we're not on this board just for fun and we're not playing with people's life. People are REAL. They're dying, and there's NWBO that stands aside. My heart is for the patients. And it's for NWBO; Linda Powers, Les Goldman and Linda Liau. Hang on. Time will tell. Don't give up.
Flipper44, I always appreciated your devotion. I hope to see you on ymb. Once you ignore a few dozens paid bashers, it's not too bad. Take care Will the (.....) manifest itself...
Friend who participated in the DCVAX-DIRECT trial
by dogood.dowell • YMB
I happened to know three people who all had stage IV pancreatic cancer with multiple metastases who were diagnosed within a short time of each other. I had become aware of the DCVax-Direct trial at MD Anderson as a result of following the development of dendritic cell vaccines after my mom passed away from a GBM several years ago. I recommended that all three investigate participation in the trial. Due to conflicting medical advice from their oncologists, two chose not to participate and use standard of care or other immune therapies and one chose to enter the trial. The two who chose not to participate have both passed away unfortunately. The one who participated is symptom free and has exceeded his original 6 month life expectancy of by an additional 9 months. His disease is currently stable. I am writing this because it would be a terrible travesty if those who are attacking NWBO succeed. Anyone and everyone who has the capacity to help NWBO by holding their stock, investing more, and encouraging the positive news that has resulted from NWBO operations will also be helping these patients who do not have any other good options for treating their cancers. My sincere hope is that these treatments become available to more patients as soon as possible.
Some of us have been waiting for a story and a stock like NWBO for over 25 years, this IS what we've been waiting for, a stock that is totally disruptive on how we treat cancer... this is NOT a stock that will stop at 125$. So...just be careful if you intend to sell it at this low level, for such a disruptive platform. This stock will go to 500$ and maybe much more. Do not forget that if you sell at 125$ or around there, big pharma will get your shares and will attempt an hostile takeover, because it is worth much more. Do not sell your shares for cheap, when you can make a fortune out of it. Just a warning. Open your eyes, never a co has seen so much low attempts to steal your precious shares, why? Because this is the real deal, what you've also been waiting for. We'll get RICH on this one. So hold on to your shares.
Or why not just keeping all our shares untill a buyout?
Hi Basin, I'm pretty new to the stock market. If you see a possible pps of 1000$ with Direct, why not start selling over 300$, 500$, 700$? Why would LP sells lots of shares that low if she can sell some much higher... and why would she ever sell NWBO..?
From Fierce Biotech:
The optimism around Prophage is welcome news for Agenus, which has endured peaks and valleys on Wall Street amid concerns over the efficacy of cancer vaccines on the whole. Clinical uncertainties for ImmunoCellular Therapeutics ($IMUC), Northwest Biotherapeutics ($NWBO) and Agenus partner GlaxoSmithKline ($GSK) have cast a pall over the field, and the commercial failure of Dendreon's ($DNDN) similar Provenge hasn't helped on the public perception front.
Well AF will probably try other tactics, and all his efforts are aiming at slowing down nwbo. But he's losing credibility, and most are getting to see the potential of immunotherapy, NWBO and it's effectiveness. We're holding pretty strong. He already knows and 'the people' behind him, that they're losing the fight. Eventhough the pps is still low, I'm not worried at all.
And 'Michael Milken, 60,000 deaths, and the story of dendreon'
is showing us what's going on behind the evil scene of hedge funds and organized crime. The treatment of NWBO is no different than Dendreon's.
And I humbly spread the news with my 150 followers on my 2 twitter accounts
Ah ah ah! Too funny
put it on the MDA facebook
The story of Rosemary Hook on the fb page of MDA is also very touching. Her husband was refused to be placed on a waiting list and died 2 months later. Real tragedies happening all the time. MD Anderson is in it for the money.
well, it's in those times we feel we're a big family sharing the same goals; NWBO with his disruptive technology that will help and save so many people worldwide. Linda Liau, Linda Powers, Les Goldman and the rest of the team, we're behind you!
Very good article Steven.
Very good post Stockfollower, I have some catch up to do for the rest.