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KenInv
Sorry to disappoint you, but you misread my post. I was complaining that both my daughter and I, in separate orders, both received Anatabine Citrate not Pure Anatabine as advertised!
Under "Supplement Facts:" the first ingredient listed reads:
"Anatabine (as anatabine citrate)
Under "Directions for use:" anyone weighing over 100 kg is to take "1 capsule 6 times per day"
Glad to hear you received PURE ANATABINE. Maybe the situation has been corrected!
Can anyone else comment on this?
All good questions to which we don't have the answers, and the same can be said for what Jonnie is up to in all this!
I am more interested to know if anyone in the USA received PURE ANATABINE, or like myself and my daughter, who ordered separately, received anatabine citrate.
We are paying for PURE ANATABINE, but receiving anatabine citrate which PREDITOR says is less than 1/2 as effective!
No one here has gotten into any discussion of why when anatabine became available again (Hydrapharm/Predator) that Predator was selling PURE ANATABINE, but Americans were receiving Anatabine Citrate, Jonnies formula.
Must be a story behind this, but can't imagine what it is!
NO, NEP, NOT THE SAME THING!
They are claiming on their website that PURE ANATABINE is more than twice as effective as Anatabine Citrate, with one bottle of PURE ANATABINE containing 150 2 mg capsules being equal to 660 mg of Anatabine Citrate.
Each bottle of 150 2 mg capsules of Anatabine Citrate we are receiving in the USA is equal to 300 mg of Anatabine, less than 1/2 as much effectiveness.
The reply I received today answering the 3 e-mails I sent to Preditor Support yesterday continues to insist that I received 2 bottles of 150 capsules of Anatabloc containing 2 mg each of PURE ANATABLOC.
This from their reply: "Pure anatabine is 115% more potent as it it not bound to citric acid."
I pealed off the label from one of my bottles and had it blown up in size so that there is no question that it says "Anatabine 2 mg (as Anatabine citrate").
I think it isn't Preditor's fault. They are just taking orders and payments, and the product is supplied from elsewhere.
Will try a 3rd time to resolve the matter. We in the USA are all paying for PURE ANATABINE equivalent to 1320 mg of Anatabine Citrate, but getting Anatabine Citrate in the amount of 600 mg.
Received my order yesterday (15 days after receiving an e-mail saying it was shipped) of 2 bottles of Hydrapharm Anatabloc. Was stunned to see that both bottles contained 150 2mg capsules of anatabine (AS ANATABINE CITRATE) rather than the 2 mg capsules of PURE ANATABINE as appears in all their advertising.
E-mailed Preditor Nutrition about this, but have not yet received a reply. Has anyone in the USA received Hydrapharm Anatabloc with PURE ANATABINE?
Also, is anyone aware of any site that is discussing Hydrapharm Anatabloc?
Need .0275 to break even, but even that seems out of reach. Was told that my Anatabloc purchase was in the mail on Feb 12, but it still hasn't shown up.
If there is a buyer at that price I'll let mine go for $100.00 per share!
Do you mean chopping block as in guillotine?
Thanks for straightening me out 1man. Chalk it up to a senior moment!
This from Archer Pharmaceutical dated 5 FEB 2018!
https://www.archerpharmaceuticals.com/news/
Thank you to upstater and powerwalker for their reply. I placed my order on a Friday when the British workday was already over, and received an e-mail on Monday that it had been shipped. That was a week ago today and today is a Holiday. Guess I am just too anxious to get back on PURE (?) anatabine.
E-TRADE is no longer showing a BID and ASK following today's small trade.
Can anyone tell us how long it took to receive their Preditor Nutrition Anatabloc from the time they received the e-mail that it had been shipped?
Happy would be the correct answer. Early this past week one of the major universities reported that an existing medication they were testing for a new application seemed to kick-start their test subjects into fat burning fasting mode.
Since so many Anatabloc users reported weight loss, as did I, I wondered if that was what Anatabloc was doing.
Does anatabine kick-start the body into fasting-mode, accounting for reports of people loosing weight when taking anatabine daily?
What's with todays RCPIQ activity? 63,000 went off @ .0018 and the ASK is 1,020,000 @ .002!
How come no one mentioned that there is a new and updated review of Hydrapharm Anatabloc at Preditor Nutrition where it claims that each capsule contains 2 mg of pure Anatabine which equals 4.4 mg of Anatabine Citrate.
All attempts to copy and paste a link failed. Also, it contains a clear explanation of the benefits of Hydrapharm Anatabine, and implies that it could have additional medical benefits!
Sadly, all three of the major pre-clinical studies ended up the same.
Reviewers found "results interesting" and "should be followed up with further studies", but none were ever done. Without those human studies there is no scientifically acceptable proof that anatabine (and isomyosmine) would be of any benefit to human medical conditions.
The financial value of any asset is whatever you can get someone to pay for it, and obviously no one was willing to offer $250,000.
I have always thought that Jonnie had a plan. Perhaps we will eventually see what that was!
In my current mode of "just wishful dreaming" I continue to look for ways in which a solution favorable to current RCPI shareholders can be reached.
It appears that the departure of the lawyers from the bankruptcy case has cleared the way for the sale of the assets (IP). If so, this would be an ideal time for RCPI to request a conversion to Chapter 11. Under Chapter 11 the way would be cleared for a combining of RCPI and MYMD Pharmaceuticals.
Since RCPI has about 180 million shares outstanding it probably would be necessary to effect a reverse split of 1 for 10 to 1 for 100 to bring the outstanding shares down to a manageable level consistent with the outstanding shares in MYMD Pharma.
RCPI shares could then be exchanged for MYMD shares based on the relative estimated potential future valuations of both RCPI and MYMD, keeping in mind that RCPI Loss Carryover can be viewed as an asset in the merger.
See, that was easy!
All we know at this point is that Bob Roskamp as well as JW Sr and some of their friends were shareholders in RCPI. We don't know who is currently on the list.
I am assuming that they are still there, and is the reason why I find it difficult to see how they could acquire RCPI without taking the rest of us shareholders along for the ride!
Interesting questions, but since I am looking for a successful isomyosmine to make it possible for JW to absorb RCPI, those questions are replaced with "what happens to RCPI shareholders?".
Here is Mymd Pharmaceyticals only trademark:
https://inventively.com/trademarks/myridine/mymd-pharmaceuticals-inc/86524156
It would be a great service to this board if you have something to say, to say it in a way that someone other than yourself can understand it!
Your post sounded quite intriguing, but a search found no relationship with RCPIQ.
Could you give us a clue or link where we could see what you were looking at?
Your Christmas posting certainly gave me something to think about besides partying.
RCPI's lending facility seemingly led to its Chapter 7 as a result of the financial hemorrhaging. In the process we have a party to the Chapter 7, who has a significant financial claim against RCPI's assets. It would seem that any purchase of RCPI's assets will have to satisfy that party's financial claim in order to effect a successful Chapter 7 conclusion.
I have posted previously that I will continue to assume that what we are seeing is an attempt to bring anatabine and isomyosmine under one roof. What would that mean to current RCPIQ shareholders?
I have no idea!
From patent # WO 2011119722 A2 whose title includes "and synthesizing anatabine" :
[14] In an alternative embodiment, methods are provided for synthesizing other minor alkaloids, such as anabasine, nornicotine, N-methylanabasine, or anabaseine. A compound of Formula I may be prepared as previously described and reacted with a dielectrophile to yield a compound of Formula IIa.
My read was that Jonnie was making sure no one could compete with anatabine by using another alkaloid.
Apologies to "ezmony".
He is correct. I probably should have been less dramatic and more accurate by not saying "We KNOW". However, I was depending on the fact that both companies connected to the new Anatabloc have excellent reputations.
If there is a next time, I'll try to be more accurate!
Luther
My thought on this was that Jonnie did much of his early patent work when he was Star Scientific and later Rock Creek. The synthesis patent was written to cover all of the significant tobacco alkaloids, and is still assigned to Rock Creek.
Attached is a description of the patent:
US Patent 08207346
Methods of synthesizing anatabine
Abstract: Anatabine is obtained by reacting benzophenoneimine with 3-aminomethyl pyridine to form benzylhydrylidene-pyridin-3-yl-methyl-amine. The benzylhydrylidene-pyridin-3-yl-methyl-amine is treated with a non-nucleophilic base and a … [more]
Inventors: Tom Thomas Puthiaparampil · Thomas Kanathkunn David · Muppala Sarveswara Raju
Assignees: Rock Creek Pharmaceuticals, Inc.
As indicated in an earlier post JWSr has been very busy filing patents, having filed five in the last few years that utilize isomyosmine to treat hair, skin, substance addiction, compositions for e-cigarettes, and the patent of all patents "Methods of Treating Cancers, Autoimmune Disorders, and Other Conditions Associated w/ Chronic Inflammation". His new company's website says that the company is near to requesting an IND from the FDA.
In summary: JWSr seems to have not missed a beat, transitioning smoothly from the RCPIQ debacle to a new love, isomyosmine, which appears to be on much more solid scientific footing. Should he have better luck in this new venture, I would expect that he would bail out Rock Creek and absorb it.
The time has come to take a fresh look at where we are regarding anatabine/isomyosmine, (henceforth anata/iso), and where Jonnie Williams Sr., (henceforth JWSr), is likely to take us.
Best to look first at what we KNOW, since there is so much we don't. We KNOW that anatabine, as ANATABLOC, is being wholesaled by a French speaking Algerian company, Hydrapharm Group. We KNOW also that it is being retailed by an English sports nutrition company, Predator Nutrition Ltd. My assumption for the purposes of this effort is that JWSr was instrumental in making that happen. If that is a correct assumption then JWSr has not given up on anatabine.
We also KNOW that JWSr and associates have formed a new company, MYMD Pharmaceuticals, whose main emphasis is to develop isomyosmine as a treatment for a number of disorders and diseases. Why isomyosmine instead of anatabine? This gets quite complicated! JWSr is responding to the work of a five man team of researchers, all of whom have a connection with Johns Hopkins, and for whom the Corresponding author is none other than Patrizio Caturegli, the same Patrizio Caturegli who was an advisor to Star/Rock Creek on the Hashimoto's Thyroiditis Study. This team has focused on Reactive oxygen species (ROS), also known as free radicals, which led to a need for a suitable MAO-A and MAO-B inhibitor.
JWSr's World Patent Application WO2016161055 A2 details a study demonstraiting the ability of isomyosmine, myosmine, anatabine, anabasine, and nornicotine to inhibit the enzymatic activity of MAO-A, and a second study in which the same alkaloids were tested for their ability to inhibit the activity of MAO-B. The results showed that isomyosmine was the most potent of the five alkaloids in inhibiting the enzymatic activity of MAO-A, and similarly isomyosmine was the most potent at inhibiting the activity of MOA-B.
The way I was seeing it, the original patent EXPIRED/FEE RELATED, but was replaced by one granted 1/4/1994, which is the one detailed in the link.
Does this mean the patent battle is about to begin?
https://patents.google.com/patent/US5276043A/en
I am committed to remaining positive about this situation until the last shovel of dirt is heaped on RCPIQ's coffin or it miraculously revives.
A thorough search indicates that our Jonnie has applied for 5 patents in which he is sole inventor, in which isomyosmine is the pharmaceutical substance, and in which the applicant was Srq Patent Holdings or Mymd Pharmaceutical.
1. US20170333415 A1 Method of Treating Substance Addictions (Mymd Pharma)
2. WO2016161051 A1 Skin Care Products Containing Isomyosmine (SRQ Patent Hlds)
3. WO2016133890 A1 Compositions For e-cigarettes (SRQ Patent Hlds)
4. WO2016161055 Methods of Treating Cancers, Autoimmune Disorders, and Other Conditions Associated with Chronic Inflammation (SRQ Patent Hlds)
5. WO2017142833 A Method of Increasing Hair Growth and Improving Hair Appearance (Mymd Pharma)
#4 is notable in its audacity as it mimics Jonnies Medical Uses of Anatabine and lists hundreds of medical conditions that might benefit from
isomyosmine treatment.
Interesting, though, is that in its claims it says that isomyosmine may be used along with other substances, one of which was anatabine.
Might Jonnie be working toward a combo since each of these substances has their own Method of Action?
Part 2:
President and Director of Mymd Pharmaceutical: Jonnie R. Williams Sr. who recently assigned his hair treatment patent application, utilizing isomysomine, to Mymd Pharmaceutical.
This story puts FICTION to shame!!!!!
For those who may be curious but not knowledgeable about Mymd Pharmaceuticals, here are some pertinent facts:
5 researchers associated with the company are listed on the website:
Giulia Di Dalmazi
Div. of Immunology, Dept. of Pathlogy Johns Hopkins School of Medicine
Dept. of Medicine, G. D'Annunzio Univ. of Chieti, Chieti, Italy
Jason Hirshberg
Dept. of Biochemistry and Molecular Biology, Johns Hopkins School of Public Health
Daniel Lyle
Dept. of Biochemistry and Molecular Biology, Johns Hopkins School of Public Health
Joudeh B. Freij
Dept. of Molercular Microbiology and Immunology, Johns Hopkins School of Public Health
Patrizio Caturegli (Yes, the same Caturegli that advised on the Hashimoto's Thyroiditis study)
Div. of Immunology, Dept. of Pathology, Johns Hopkins School of Medicine
Dept. of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health
According to the attached site Jonnie was in on the forming of Mymd Pharmaceuticals in 2014.
https://www.corporationwiki.com/p/2gd82v/mymd-pharmaceuticals-inc
Looking like the isomyosmine in Jonnie's latest hair patent is a ROS (Reactive Oxygen Species) inhibitor, which is what Mymd.com is all about!