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LOL, you just gave me a big chuckle, albeit I think unintentionally, but just the same, thx HYPEROPIA for starting a sentence with “in hindsight …” didn’t know which way to look :) … ok geek humor done, sorry all …
ATL, precisely my thought exactly!!!!
I kept holding back from responding, but with each comment re max $12 billion valuation & how happy they’d be with $10, sure seemed like a concerted swarm by a few to sway/skew expectations. BS IMHO
Cap (now in Augusta)
IMHO, the only way sense can be achieved re fung_derf’s post is via the “ignore” function.
Yup, Dean Kamen. Has a problem solving/inventing facility on the Merrimack River in Manchester NH. I was there when he testified before a House Committee on Technology, Innovation & Patents. Only person I ever saw testify before Congress wearing denim jeans & shirt. Every committee member was there, rapt at what Dean had to say. Great, down to earth guy who, along with his team, solve real world problems, designing artificial hearts, wheelchairs that climb stairs, not to mention in DC the ubiquitous Segway for tourists. Designs, licenses out and moves on to next invention. (And as Captain Obvious noted, wiki is wrong, still alive and innovating.)
ILT,
I’m totally in agreement! Certainly woulda been nice if Pr was re MAA filing, but I appreciated the PR, the transparency, and feel comfortable filling is imminent.
Cap
Agreed, no idea where the consultant(s) is/are located either, if it’s even relevant, but there surely are a number of them in the UK. Aside from Kings & Ashkan, there’s the Advent folks, and I think statisticians are located there, not to mention MHRA regulators. Who knows?
PS Apologies to all for typos my prior (and other) posts. I really need to proofread before sending, but never have … old dog syndrome:)
Life balance can def affect outcomes in the real world!
I was involved in billion+ dollar sale/acquisition transaction, where the seas were parted/issues mandated to be resolved because the acquiring CEO (European) had a July vacation plans and was not going to disappoint his grandchildren by changing them, even though this was a critical transaction. This, the marching orders from the PE/VC owner/sellers to this deal was; resolve/remove any material remaining obstacles to closing the transaction … they were … and the deal was signed off on & went through by his vacation.
So if conjecture by some that a purported upcoming 2 week UK/EU Fall school break did perchance have any relevance/bearing on the 2 week delay mentioned in the NWBO PR re a consultant’s availability, if that necessary person is located in the UK/EU, I don’t find it unfathomable that whatever is needed of that person would simply have to wait. Personal priorities can vary greatly depending on whether in the US or UK/EU.
Doc,
Completely in agreement, ever impressed with folks here, including yourself!
Cap
It’s an even smaller world, as I know Vint & Sigrid as well. And while he & Bob Kahn are credited as being the Fathers of the Internet due to their developing the TCP/IP protocol @ DARPA, he did not receive the Nobel Prize for this work. However, he did receive the Turing Award among his many awards & accolades, which is often referred to as the Nobel Prize of Computer Science. After he left UUNET/WorldCom/MCI he went on to be the Chief Internet Evangelist @ Google.
Agree, always thoughtful/insightful comments, thank you.
QL300, thank you, these comments re litigation & motion process are imho spot on and helpful to the uninitiated. Appreciate your, Cap
Arguments focus on the positions/arguments submitted by the moving/opposing parties’ briefs + whatever the trial judge wants to address. It’s more open-ended than appeals, which are generally locked in by the trial record & arguments related thereto.
Hoff,
I agree it’s a good decision and helpful vis-à-vis defendant’s MTD briefed argument, and I’m sure you know this, but for others I would like to clarify: the Herrington decision is NOT governing precedent in our case, so school’s not out, but may be persuasive to our Judge and a ruling on the MTD in NWBO’s favor. Just trying to make sure to keep things in perspective and not get ahead of ourselves.
Cap
Amen to that, it would be greatly appreciated !!
Vikinginvest: “Instead of just reposting Mav’s posts, could you translate them for those of us who need it?”
Superb effort, thank you Hoff, kudos & respect to you! Cap
Second your using the block option & also used it for two posters: the one here you keep giving air to & fish person.
Doc, that is my belief (and hope) too!
GLTU and those afflicted with this horrible disease.
Best, Cap
“Nothing wrong with that, It's just as speculative as the other posts on this board”
That’s kinda what I thought when I posted it. Lots of recurring, infinite-loop topics & discussions as we all wait, so figured why not something new/different.
Caveat: This is just a passing thought that occurred to me reading an article and thought I’d share. Again, to emphasize, I’ve seen ZERO in the ether to give this any credence, but I liked the thought nonetheless:
With Steve Jobs’ son, Reed, starting up the for-profit Yosemite VC fund to invest in fighting cancer & funding research, with over $200 million in funds already, I just thought it’d be so interesting if that somewhat curious $3 million NWBO mentioned came from Yosemite.
https://www.forbes.com/sites/irenebenedicto/2023/08/01/steve-jobs-son-launches-new-vc-firm-with-200-million-to-fight-cancer/?sh=4fe2c6ed65b5
Yup, agree and see it that way too, thx!
Completely agree with Bio, Gary and sentiments similarly expressed by others:
I think these kinds of efforts are not helpful & are counterproductive.
Cap
It may also be called the “Prisoner’s Dilemma,” and the same thought has crossed my mind as well, Branster.
It’s hard to assess likelihood, but sure would be an interesting development, and not out of the realm of possibilities.
Cap
Bio, we’re good, I appreciate you and all your contributions to this board.
Cap
Bio, I completely agree, and am not interested in settlement offers or awards, likely years down the road, but about what comes to light during discovery.
I’m quite familiar with large, multiparty litigations, particularly those involving well-funded defendants. Assuming the Defendants’ 12.b.6 motions are denied, and NWBO’s SJ motion is too, then we’re on to the world of defendant’s entering Joint Defense Agreements for certain cost-sharing, endless Discovery motions practice, etc. It’s a marathon, with NWBO’s goal to discover all you itemized, and likely more, then holding defendants responsible during a jury trial.
So I was only specifically commenting on the thread re whether any supposed $100 million or $1 billion settlement offer should be considered. My point in mentioning the magnitude of defendant Citadel’s earnings was simply to say that, assuming damning information comes out about defendants actions & manipulation are unearthed in discovery, a jury could well make a significant statement, that’s all.
Just all IMHO.
I know CVM is not highly regarded by many, but their PIII data clearly reflected the same vis-à-vis chemo suppressing immune system response to treatment. In the CVM trial the chemo arm resulted in missing the clinical endpoint, whereas the non-chemo arm not only met, but exceeded the endpoint goal.
Cap
I agree with Bio and others too. $100 million is simply a nuisance value settlement offer, if even made at all.
More to the point, though, with lots of IFs involved, but if this case goes to trial, and if NWBO prevails, and if defendant financials are allowed in as evidence, the fact Citadel ALONE made $17 billion last year, could well prompt a jury to award a HUGE verdict, including significant punitive damages, esp since the alleged bad actors we’re trying to bankrupt a company with a vaccine that could help extend — if not save — the lives of those afflicted with GBM. Just MHO.
Cap
Thanks Gary, I understand and get all that.
Apparently, I in-artfully said what I meant, which was that the FDA “officially” adopting the point of Padzur et al Annuls of Oncology article’s re evaluating PIII results vis-à-vis ECA OS data, and that that could act as an additional potential catalyst to the ATL’s list of NWBO-specific catalyst re SP.
ATL, thanks, naturally agree with all those, plus would add a potential side kicker benefit of the FDA, one of these days hopefully soon, officially recognize and accept OS as the standard.
FYI, re taking a big step Fri/Mon, wanted to remind folks that the market is closed this coming Monday, Federal holiday.
Ummm, ok, I didn’t assume otherwise.
Kpauliukonis, thanks for the meeting synopsis. That was the tipping point of deciding not to drive to Northern VA for the meeting, ie, no advanced PR.
On the heels of a positive response @ ASCO, then Geert’s presentation at last week’s LD Micro Conference, I was looking for/expecting a PR by last Friday (or at the latest premarket today), and absent either, figured I wait on a post-ASM PR.
Sounds like I’m glad I decided not to go to the Annual Meeting, even though it was only a 20 min drive away … wasting my time would’ve only added to my already significant frustration …
Does anyone have info on how to virtually attend today’s Annual Meeting? Thanks!
This is a nice piece on Nate Bilinsk from 2017. And while Nate sadly ultimately lost his battle with GBM, DCVax treatment gave him the precious gift of time.
Far as I can tell, he was diagnosed with GBM in 2011, recd his first DCVax treatment in 2012, the last 2014, and was blessed to have lived >8yrs more after diagnosis, thanks to NWBO & DCVax.
RIP Nate (1989-2019).
trctrader38,
I’m flying to Monroe MI tomorrow for a memorial service/celebration of life for my dear friend Jill. I am there til next Monday.
Any sense how pervasive Covid is in the Monroe/Newport areas by Lake Erie there?Thanks.
Cap
If it’s the person being conjectured about, of the 3 of 4 positions listed, tenure was just a little past the 2year mark, so looking for a move now, for whatever reason, fits the timeline history, FWIW
Amen, with ya on that.
Everything in time, one way or the other, but these minor perturbations daily for the upcoming month are not the game.
Btw, I always look forward to your allotted one post per day, thx!
Cap
Yes, awaking to news our dear friend & longtime local NBC news anchor, Wendy Rieger, passed Easter morning greeted us all in the DMV metro area, a very sad awakening.
She was diagnosed with GBM about 12 months ago, had surgery & treatment (not NWBO), then retired in December, intending to savor life with her long-time companion and new husband, Dan, only to succumb to cancer when it returned aggressively several weeks ago. She was just 65.
Wendy was an amazing person, a life-force really, with a wonderful blend of humor, intelligence, warmth and compassion. She was an advocate and supporter of many causes, where her involvement was never superficial, whether it be trying to save animals, mental health wellness, equal rights, and so many more.
We can not get NWBO’s treatment approved and saving lives fast enough :(
Precisely!
Thank you Bio, I appreciate you and so many others who make meaningful contributions!