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UK preparing 'public health response' after H5N1 virus jumps from mammals to humans in pandemic escalation
https://www.gbnews.com/health/bird-flu-pandemic-symptoms-2024-vaccine
Should Merck Buy Out Moderna on Keytruda–Cancer Vaccine Partnership?
https://www.biospace.com/deals/should-merck-buy-out-moderna-on-keytruda-cancer-vaccine-partnership
"from where I'm looking, the world is flat." NO VAX LOL
Sangamo Therapeutics (NASDAQ: SGMO) and Pfizer (NYSE: PFE) have reported positive Phase 3 results for giroctocogene fitelparvovec, a gene therapy for hemophilia A. The AFFINE trial met its primary and key secondary objectives, demonstrating superiority over routine Factor VIII replacement therapy in reducing annualized bleeding rates. A single dose of the therapy significantly reduced mean total ABR from 4.73 to 1.24, with 84% of participants maintaining Factor VIII activity >5% at 15 months post-infusion. The therapy was generally well-tolerated. Sangamo is eligible for substantial milestone payments and royalties if the therapy is approved and commercialized. Pfizer plans to discuss the data with regulatory authorities soon.
President Biden finished his 10th course of Paxlovid today; symptoms have resolved “almost completely,” update from his physician says:
https://www.whitehouse.gov/wp-content/uploads/2024/07/Letter7.22.2024.pdf
FDA Gives Dendritic Cell Vaccine Fast Track Status for Pancreatic Cancer
https://www.cancernetwork.com/view/fda-gives-dendritic-cell-vaccine-fast-track-status-for-pancreatic-cancer
President Biden tests positive for Covid with mild symptoms, per White House, and has received first dose of Paxlovid
Moderna to Report Second Quarter 2024 Financial Results on Thursday, August 1, 2024
Experimental mRNA Vaccine Hints at Potential Against Glioblastoma
https://www.cancer.gov/news-events/cancer-currents-blog/2024/glioblastoma-mrna-vaccine-layered-nanoparticle
I agree 1000%
Stock Dividend $$$$$$$$$
$MRNA golden cross on MACD
Bird flu virus infection is usually diagnosed by collecting a swab from the upper respiratory tract (nose or throat) of the sick person.
https://nymag.com/intelligencer/article/cancer-treatment-immunotherapy-oncology-tcells-brain-tumor.html
“I think by 2029, we’re going to have FDA approval of CAR-T cells for glioblastoma,” he said. “It’s going to be a huge thing, and 2024 is going to be looked at as the breakthrough year.”
THE WRITING IS ON THE WALL
Melanoma cancer vaccine results “extremely impressive”
The first vaccine treatment for the form of skin cancer usually caused by sun damage could halve the risk of patients dying or the disease returning, according to early trial results.
Researchers led by a team at New York University combined a vaccine using the same mRNA technology as many COVID jabs with an established immunotherapy called pembrolizumab. It was given to patients after they had surgery to remove stage 3 or stage 4 melanoma.
After three years, 75% of those who had the vaccine and pembrolizumab were still cancer-free, compared to 56% of people who only received pembrolizumab.
Iain Foulkes, our executive director of research and innovation explained that the results “show positive signs of the mRNA vaccine’s long-lasting effectiveness”, although larger and longer trials are still needed.
Unlike traditional vaccines, which are used to prevent disease, cancer vaccines are used to treat cancers. The vaccine used in this trial, mRNA-4157 (created by Moderna), is different for every patient. Scientists personalise it to help people’s immune system identify their specific cancer cells. Pembrolizumab, a type of immunotherapy called a checkpoint inhibitor, supports this by effectively taking the brakes off of immune cells called T cells.
Speaking to journalists at ASCO, Swanton called the results “extremely impressive”.
“The new vaccine approach is another piece of the puzzle that will allow more patients to be cured, hopefully, or fewer patients to suffer disease relapse. Ultimately it will contribute to survival rates improving continually over the next decades and more.”
“Obesity is a key therapeutic area for Pfizer, and the company has a robust pipeline of three clinical and several preclinical candidates," said Pfizer's chief scientific officer, Mikael Dolsten.
"The most advanced of them, danuglipron, has demonstrated good efficacy in a twice-daily formulation, and we believe a once-daily formulation has the potential to have a competitive profile in the oral GLP-1 space."
Santa Claus is there NO VAX
Bridge RNA: A new gene editing technique that could overcome the limitations of CRISPR
https://www.labiotech.eu/in-depth/bridge-rna-gene-editing/
‘It’s Going to Be Catastrophic’: Why the Next Pandemic Will Be Worse Than COVID
https://www.dailysignal.com/2024/07/08/chinas-covid-deception-cost-us-18-trillion-1-1-million-lives/
$NOVAX
Ended the quarter with $7.8 million of cash to fund operations 
long live the pussy NO VAX
heal your brain.... useless NO VAX
Bird flu spread to cows takes 'dangerous' step towards infecting humans through respiration, scientists warn
https://news.sky.com/story/bird-flu-spread-to-cows-takes-dangerous-step-towards-infecting-humans-through-respiration-scientists-warn-13175177
In a 153-page written ruling on Tuesday, Mr Justice Meade concluded one of the European Moderna patents, labelled EP565, was “invalid”.
But the judge said a different patent, called EP949, was “valid” and was infringed by Pfizer and BioNTech.
A Moderna statement said: “We are pleased that the UK High Court recognised the innovation of Moderna scientists by confirming the validity and infringement of the EP949 patent and that (the) defendants were not entitled to use Moderna’s patented technology for any infringing activity after March 7 2022.
https://www.standard.co.uk/news/crime/pfizer-moderna-high-court-netherlands-germany-b1168104.html
Looking for the Best Health Hacks- Try Vaccines "anti-vax"
https://www.scientificamerican.com/article/vaccines-are-the-safest-health-hack/
Moderna secures partial victory in Covid vaccine legal fight
https://www.ft.com/content/c57bc08f-50b3-42ef-ad44-4d592b189ce7
Scientists wary of bird flu pandemic 'unfolding in slow motion'
"It almost seems like a pandemic unfolding in slow motion," said Scott Hensley, a professor of microbiology at the University of Pennsylvania. "Right now, the threat is pretty low ... but that could change in a heartbeat."
https://www.reuters.com/business/healthcare-pharmaceuticals/scientists-wary-bird-flu-pandemic-unfolding-slow-motion-2024-07-01/
10 clinical trials to watch in the second half of 2024
COMPANY: Moderna
DISEASE: Cytomegalovirus
TREATMENT TYPE: mRNA Vaccine
There are no vaccines for cytomegalovirus, or CMV.
Success would also open up the potential of a product analysts think could eventually generate more than $3 billion in peak yearly sales.
https://www.biopharmadive.com/news/biotech-10-clinical-trials-watch-2024-second-half/720005/
bouncer...