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Definately. It will take a combination of all to meet demand.
I took a much larger position after RGLS crashed after stopping trials on it first drug candidate in favor of the one they are pursuing now. Did you know Regulus was started by a collaboration of two BPs and the scientists of Regulus came from the research divisions of those BPs?
welcome. I followed you which I do not do often because I looked through your posts and saw you posting on some stocks I have been in for over 20 years like Plug Power and Fuel Cell. wow was I way to early on those. I had thought in 2000 that most cars or many cars would be hydrogen fuel cell powered by 2010. Instead they are pushing litium battery powered cars which are an ecological disaster or will be soon.
This post is an example of emotional investing which is one of the worst mistakes one can make. You evidenced this by the comment "this angers me". Try to control emotions and to rely instead on solid DD evaluated by rationality and logic. Refuse to be a victim and hold to convictions based on DD. Stock price drops benefit the confident long-term shareholder that methodically accumulates. Emotional reactions lead to losses. I see lots of posts that promote emotional investing. It always makes me cringe. It must be a common affliction. Get over it for your own good.
A recent Cancer Drug was approved by FDA with a simultaneously released NEJM article.
GSAT is a well backed company with some big institutional investors. It has a over $3 billion market cap. Which makes it a small to mid cap company not a penny stock. It is a new player compared to the other communication satellite company. Therefore it has the most debt as it is in start up mode. It also means it has the latest and best technology as well as the newest satellites. It plans to be the major player in The Internet of Things (the major future evolution of the internet) connecting things like ships at sea, remote cell towers and major industrial installations. They most importantly OWN the radio spectrum the Qualcomm built in connection to its latest communications chip. This Qualcomm chip is in the iPhone 14. Apple is paying for 90% of the new satellites that will be launched and GSAT only 10%. This should add some debt to GSAT but only 10% of the costs of this tremendously valuable asset on the cutting edge of IoT. GSAT is setting up to be the major player in Satellite Communications and IoTs. This requires debt but Apple is paying 90% of the cost. This is an incredible deal for GSAT they are in effect partnered with Apple and Qualcomm. This might also signal Apple and Qualcomm are moving in on IoT heavier. This might not be about satellite phone connection at all but about Industrial connections to the IoT. GSAT owns the Real Estate here on this very important spectrum. It is the spectrum that Qualcomm and Apple chose so they are in effect tenants of the Real Estate GSAT owns and Apple is paying 90% of the costs to the improvements of the Real Estate so it fits Apple's purpose. It looks like GSAT Apple and Qualcomm are is stealth mode until they can capture the most important
future market share of IoT.
This looks to be a long term investment that might turn into a monstrously profitable enterprize.. It also bodes well for Qualcomm and Apple to establish a major position in IoT.
very strong clinical science
The worst ecological disaster that is facing the world right now is the transition to EV because if the hyrdomining required to produce the rare earth elements to make the batteries. It sucks the ground water from the head water sources in Canada and China. In Kansas and other plains States the aqufers are being depleted. When it dries up the world will starve. California had a viable solution with the Honda hydrogen fuel cell Accord that debuted with testing there. But of course they took the greed course of battery EVs.
EV just exports the pollution to mining areas so smog in LA could be reduced at an extreme cost to the planet.
Clearing of rain forests may be a higher
contributor to excess CO2 than fossil fuels. We can plant large bamboo forests and kelp forests in the Oceans to repair. But we can not recharge a dried up aquifer. They took millions of years to form and when they are gone they are gone.
Gréen Hydrogen, Nuclear, and fast growing plants like bamboo, kelp and hemp might be better solutions. But with out the aqufiers the world will starve before Miami is under water or LA and Denver are smog free.
Many farmers in the plains States are having to redrill their irrigation wells because ground water is being depleted. One Kansas Farmer feeds 68 people and YOU!
ZIM is not a new company. Established in 1945 and have a stable 77 year history. ZIM was just recently listed on the US Exchange. ZIM is not well understood. It uses State of the Art logistics technology. It is a shipping business but a technology company.
Yes. The Pediatric Indication Plan now approved. That was a condition precedent to filing for full approval in the UK.
Is it not also true that NWBO owns the patents on the NWBO drug in combination with check point inhibitors such as and including Keytruda and not Merck?
Therefore for Merck to realize benefits of the Combo they would need to come to a Royalty/Partnership agreement with NWBO or buy NWBO out.
It would seem that Merck shares your deduction. Therefore, Merck got a jump on the competition by starting its Combo trial with the NWBO proxy drug (same drug different name) as stand in for current SOC protocols. After all if DC-Vax becomes SOC then all trials using current SOC as placebo will lose significance. Merck sees the writings in the Halls. Why is this so difficult for others? Oh maybe the oft repeated fallacy that the UCLA drug is different. Accepting this fallacy would force one to accept a completely illogical action of Merck to chose a Placebo arm which will never even have a chance to be SOC.
It trials such as the Keytruda/UCLA ATL-Vax (experimental version of NWBO drug) where ATL-Vax is the Placebo arm, the standard of care drug is chosen as the Placebo.
So is not Merck projecting or calculating that DC-Vax is highly likely to be the SOC by the time the Combo trial sequence reaches the Phase 3 Registration trial development stage.
If filed NWBO will not say so. If not filed NWBO said so. Now they are not saying so expect the next statement on the subject will be that the filing was accepted or rejected. If the filing is rejected NWBO will need to disclose that in an 8K with in 4 days per Reg. FD. If the filing is accepted NWBO could delay the announcement potentially up until a ruling on the application or an offering of stock.
Personally I deduce that it will be filed and accepted prior to the ASM.
Just an observation. NWBO could not have filed for approval in Great Britain without first having the plan for the pediatric trial approved. Now that is approved with a N of 24. Nice! Condition precedent achieved. The trial does not have to be started before filing for approval in Great Britain just plan approved.
So now it seems the final filing for approval could come any week.
Come on NWBO shock and awe us with an accelerated news cycle.
Evergreening Keytruda patents will not maintain Merck in a dominate position in Cancer Therapudics. Science is moving forward. Merck and other Cancer BPs must hitch their wagons to the new pioneers in Cancer Science to make to the new frontier. NWBO and Dr Linda Liau are some of the new pioneers. What is more is that NWBO is also pioneering a new manufacturing method.
I will confidently say that any one that has taken a close look at the NWBO venture and can not see the paradigm shift coming may never hitch their wagon to a huge Biotech in its infancy.
This could take a few more years or it could flash over in 3 to 18 months. When taking the pioneer trail the roads are rough and the maps are not reliable. Nothing this important is easy. Expect to have to grind it out.
That is exactly right. A Company can not maintain its own dignity while dignifiying outrageously false claims of critics like AF with a rebuttal or law suit.
If there are third party experts that respond to the false claims that is well and good but the Company must not get embroiled in the kerfuffle. We have seen AF being rebutted Twitter same. If there was malice by improper motive such as consideration of some type afforded to AF such as money or favors behind the dumpster at Wendy's then that is an action for the Justice Dept. Don't hold breath for that to happen. Justice will never smoke that out they have much fatter juicier burgers to fry.
An elegance of the quiet period of NWBO is that they can maintain dignified indifference to all of the words of critics and the actions of AF behind the dumpster at Wendy's.
The continued and accelerating progress of NWBO on manufacturing and regulatory fronts will be complete and utter vindication.
This is a made up fantasy. Even as a piece of fiction it is poorly thought through. How could one cover short common shares with Long C shares that can not be converted to common shares for 90 days? One still would need to buy coming to cover the short common but that dull trader expended the capital needed to buy the common on restricted C shares.
If you want to butcher logic I would suggest you reach in the drawer and find a sharper knife.
AF may have gotten involved with the wrong mob ere I mean "crowd" from Howard Beach and now he can not get out because there is only one way to get out of that "crowd". They have the interests to protect at the "Family" offices. If he is a good boy they will meet him for lunch and bring him a paper bag lunch which he sticks in his pocket because he will need to split that bag lunch with someone else.
The night king of biotechs sits on the throne of Damocles.
Options trading is like a casino. The House is always on the other side of the trade. Even if another player wanted the other side the House steps in to fill it and when it moves against the other player the House steps in to fill that order.
On big trades in options like that 99% of the time the Market Maker takes the other side of the trade. So the MM is short all those options but they will buy back piecemeal as the time value decays.
Excellent.
Getting in too early is much better than getting out too early just before the big hockey stock formation.
That is right many have and many will. RA approval in not necessary to advance from Market caps in hundreds of millions to multi billions. The element that causes the stratospheric upward valuations is "market recognition" of the potential. For instance Arrowhead Pharma rose from $200 million Market Cap to $7 Billion Market Cap in 18 months(35x) before any drug approval. Look at ARWR 20 year chart. What caused the "Market" to finally grasp ARWR potential was likely the JNJ partnership. Anavex Life Sciences rose from a share price of $1.26 to a spike of over $30 in 18 months. On no drug approval or even partnership. Likely the "Market Recognition" for AVXL came because how the Market was revaluing Cassava another company targeting ALZ.
Look at the 20 year chart of AVXL.
NWBO in its current depressed valuation is like sweating dynamite any little shock from positive news could cause it to explode upwards. Look at the 20 year chart of NWBO. Then view again the 20 year charts of ARWR and AVXL. If one wonders if Cancer Companies have the potential of 25x revaluation on market recognition in just a few months then try to find a 2017 chart of Celator CPXX.
Make no mistake, NWBO at its current valuation is like wet dynamite. I do not know when and what what will cause it to explode just that likely it will explode and it might not take a big catalyst to set it off. The Market will not wait for approval to revalue NWBO I can nearly guarantee that much.
Wrong thinking Linder Powers is just now entering the power band.
Yes we are looking for an organic non GMO uplift. No reverse split. Organic development based stock price appreciation followed by C preferred stock sales in am amount to yield the minimum stockholders equity requirements. Certification of manufacturing should be the dam buster.
Anyone that does not believe that radical upward price explosions can happen and be sustained should study the Celator Pharma chart from 2017.
It is always refreshing to read your posts. Rational not emotion based and neither pumping or fear mongering. Thank you for sharing your thoughts.
This second group of which the University of Pennsylvania study delineated would as to stock investing promote investing by emotional responses whether greed and FOMO (pumpers) or fear, doubt, resentments, bitterness, jealousy and resentments (neg Nellies and Debbie downers). The stronger the emotions the worse the investment decisions.
I saw a T-Shirt advertised on a stockcharts website. Printed thereon was the saying "There is NO FIX FOR STUPID and STUPID CAN NOT BE QUARANTINED EITHER" They will be there on social media as misery loves company and they are there to suck you in to emotional trading decisions.
Warning do not get infected by emotional investors. Emotional investing can cause a lot of financial damage. No FOMO! No FEAR!
Controlling emotions can cause a lot of internal stress as one must internalize the responsibility instead of projecting in on the "shorts" the FDA or Management.
One might instead make a plan and stick to it and when based on logic and verifiable empirical evidence that the situation has changed move deliberately
and decisively in rational measured steps. But NEVER EVER based on emotion.
One reason for technical trading is to help one remove emotions from entry and exit decisions. TA is hard to master but even if one is not adept it helps one master ones emotions which are the greatest threat to successful investing.
I would go one step further and suggest in the long term stock price and TA become less relevant proportially to ones hold period. For investment grade stocks balance sheets, market share and defensible moats are infinately more important. For speculative stocks the risk/reward ratio and potential addressable market value are what are important.
NWBO has an astronomical risk/reward ratio and a large addressable market eventually beyond Brain Cancer. NWBO is somewhat unique as it is traded on the OTC, while being close to several binary events regarding manufacturing and RA approval, which is artificially depressing the stock price. NWBO will up list or be killed. Management knows that. Series C preferred are the vehicle to up list. Logic dictates this based on the NASH Equlibrium. NWBO had never deviated from the initial strategy. Which is RA approval and control of manufacturing.
Buy Out is not and never has been part of NWBO strategy. Sorry get rich quick investors (frustrated traders).
NWBO is the Turtle that makes it to the finish line slowly and deliberately. No reason to suspect that NWBO will morph into a Hare and sprint the rest of the way.
For my investment thesis NWBO is purchased with the intent to NEVER sell at any price.
One should understand that the wealthy never worry about taxes on investments Captital gains as they never sell. If want money they borrow against the stocks as collateral from MSSB or Citi accounts intestest paid from dividends on same assets they can use those funds to purchase other income generating assets.
"When it is raining Gold put out a bucket not a thimble" W.B. Who BTW even a billionaire will not buy a car unless it has already 10 years old. Whether a Maybach or a Lexus I do not know. I will take the Lexus as low maintenance in equipment as women is very important.
Judge that is a lot more excellent detail. Thank you. Looks like a potential inflection point. Thank for the chart I took a screen shot of that one. You a a real technical pro and a gentleman.
Stochastics are close to bottomed out. So might be a good time to add which ever way the price breaks. I would Definately Buy a head fake to the down side and buying on the way up has charms as well. I do not look for opportunities to sell just opportunities to buy at a discount to long term value coupled with a nice short term entry point.
I imagine the unethical dweeb AF knew that NWBO could not respond to his hit article because of the embargo. However this was actually preferable so as not to dignify AF's article with a response.
Good news from a technical analysis stand point is the Bollinger Bands on the daily chart as of today are constricted. That portends a move from this tight range whether up or down. The main thesis of John Bollingers thesis is that periods of low volatility are most often followed by periods of high volatility but the B Bands could remain constricted for weeks or NWBO could move sharply Monday.
I have no idea why a market maker might be calling NWBO. I might help to understand how MMers operate. To make a market in shares of a Stock a MM has to have an inventory of shares. They can borrow shares from a Wire House wealth manager like GS Morgan Stanley or Citi (Wire Houses make a market in the inventory of MMers)or they can buy long shares. Either way they trade them back and forth from either their short inventory or long inventory. Also if they want to keep making a market in a Stock after an Up List to another exchange they might need to adjust their stock inventory in some manner. Also a possibility that a new MMers wants to start making a market in NWBO.
I read that opposite as the number of shares available to borrow means that short sellers are covering down here believing it has no further room on the down side. Therefore might mean that some of the bearish sentiment is subsiding. Also a greatly increased bearish postings often coincide with short covering to attempt to keep the price suppressed while buy cover trades are being executed. Any little piece of news might cause a big spike in this low price ebb dynamic.
Damage to shareholders? What damage? A lower price for a Company that an investor has confidence in ultimate success as well as the Investors confidence of one's own ability to to recognize a good investment? It is extremely foolish to one to need to have the share price reinforce the Investor's confidence they made a good investment. Pick a good investment and hold it forever. One should not have an emotional reaction to a rapidly falling share price when it is an illogical and an emotional traders reaction but rather carpe diem and load the boat. "When it rains gold do not put out a thimble put out a ( the largest one can manage) bucket" W.B.
Trade rarely but when trading do it with conviction and switch horses for the eventual winner that suddenly became an ridiculously underpriced asset.
May 10th was a gift to the confident long-term investor to accumulate at a ridiculous low price.
Of course. Advent taking payment in shares not only shows confidence in the NWBO venture but also is an incentive for performance as increased efforts and efficiencies might result is a greater future value of the shares. Rather than being just a vendor Advent has "skin in the game." Other characterizations are illogical negative spins.
A breath of fresh air.
Investing on logic,
rather than bitterness and despair.
Ha ha, yes I did. Learn to control emotions and you might not miss the NWBO ballistics in 6 to 18 months.
Ha ha! You are joking again right? Right? Hearsay from an anonymous poster requires a leap of dispair to get from point A to point B. Bitterness and despair. Strong Emotions! Pity pity. Has no one ever schooled you on the fact that emotions and investing do not mix? The worst decisions are made out of emotions. The stronger the emotions the worse the decisions.
Quiet down crickets. Your basis for what you are asking for examples of have no relevance to investing whatsoever. Cancel the meaningless "investor group" and replace it with BP and you have the answer to the reason for the investment. I direct your attention to the Arrowhead/JNJ deal of 2018.