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very astute thinking biocect. The shorts objective has always been to change the conversation from actual trial results to less important conversations.
Thanks for keeping us focused. All that matters is the data and how nwbo has been proactive at manufacturing.
I will say from my due dilly that nwbo is the furthest ahead in manufacturing of the new cell therapy companies I follow
So will fda approve these new cell therapies in Sept or october before the midterm elections? We can include Athx for stroke and mesoblast for heart ,back and other indications. We know the groundwork papers have been written and discussed here.
Its no secret that all the cell therapy companies are spending big bucks on manufacturing. And basically they have been told no approavals until batch constincey is validated. Meso for gvhd was denied even with great efficacy.
Anyway Biden needs a success story. If he can give hope that people have a better option than chemo thats huge.
If cell therapy treatment for heart disease stroke chrohns and other diseases can be announced thats a huge win.
The public is fed up with crappy treatments that dont cure the diease.
The public is aware of the excruciating slow new drug approvoal process.
I think the dems have been working on this for quite a while. Take me to the moon...
Thanks for the insight Jimmy the third. Nice perspective.
It was unfortunate that we didn’t get the huge numbers that most of us were expecting. Hard to rationalize how the data got so much worse than the 2018 data.
That said this trial is very successful compared to anything in history and the potential with adjuvants is mind boggling.
This trial took so long I believe throughout the years they figured out ways to improve efficacy. Iam thinking the last 40 patients enrolled may have lived longer because of improvements in manufacturing or other
This is a first in class of a new paridigm treatment
Holding firm into the future. Gl believers
Big money wants to keep price down before news to accumulate lots of shares on initial tld. Bigmoney wants this to open up just around where stock might be marginable so no money can be borrrowed on it. Shares will have to be sold to access capital. This is the initial plan of possible buyers of the company imo.
And my guess is the appeareance of Adams name listed at the top of our well read board is to put some fear into potential and current nwbo investors. Perhaps on positive data release long term shreholders should take some profit as manipulation can happen like Amrn.
Remember if this stock was a fail the big money would be pumping it up to short it. As it is now they cant accumulate stock down here so theyre plan is to accumulate from a lower base on news. Thats why its worth their while to short a few million shares down here to collect many more millions of shares from a triple on news.
My guess on first day of tld is open 5 bucks then go below margin 3 bucks at end of day But it does not matter ecause the big money play is to take the shares from retail investors that have been there so many years.
Iam not selling or trading on tld Personally I am waiting for other milestones. Gl my friends!
Here is a few things that we know. No pumping of our stock or potential for 4 years. Loans to company instead of dilution for last year and a half or longer. Insiders have not sold shares. Multiple milestones accomplished in last 18 months.
And thanks to Danish dude,Biosect,Flipper,Iwasadrinker and so many others that made me feel ok buying lots of shares between 35 cents and 15 cents. Personally I started loading bigtime after the Asco blinded results in 2018
Best of luck to my fellow dreamers and visionaries !
Nwbo is definitley holding its own compared to every other cell therapy company I follow. We are looking quite good technically. I see the same setup in the other promising biotechs but they are testing 5 yr lows.
Holding this market cap on otc with no news for a year is impressive.
Good luck fellow visionaries
Anyone else sometimes think that this trial is so huge that it will be rolled out as the flag for adoption of the new tharapies that actually cure people.
Biden said he wanted to cure cancer and then went silent.
Fda regulations have been changing to accomodate approvoals of new tharapies that actually cure. There is a huge bottleneck of cell therapy trials at phase 3 that warrant quick approvals. Heart disease,stroke and backpain to name a few.
We have a new guy coming in to lead fda. He seems progessive.
In my opinion Biden should announce these new successes and then propose 100% access to universal healthcare.
I dont want to make this political but someone has to take credit if a new paridigm shift comes and finally occurs.
And when it does get announced they will be able to say manufacturing is in place to treat a substantial number and we are working to increase capacity.
Thanks again Flipper for sharing your extensive knowledge.
I looked up bfd .. big freakin deal. ok got it
So nejm hypes up this new scenario to evaluate trials.
Is there any trial other than our trial that should be the first highlighted?
This is getting exciting. And for some reason since 2020 the journal rumor has been nejm.
Makes sense that nejm scientists want to be on the right side of the new disruptive technology.
That will allow Biden talk about it
What I take from the press release is Nejm is backing a more progesssive way to evaluate clinical trials. And more spescific to cell and gene therapy trials.
They are promoting a new cutting edge peer revued paper that proposes why new clinical trial endpoints should be accepted before trials are unblinded.
A precussor journal article before the big show.
Coffer Black is coming I do believe, This will be his finest moment and he will leave the legacy for his name and family. Remember that strong men that must make tough decisions would like to believe they are moral altrustic people down deep. I believe he always told himself he was making the best decision for the best outcome.
This will be a crowning moment... The guy has not talked about anything in 6 years...
You think he likes Clint Eastwood movies ?
new posters off top of my head
biovest slamminsalmon 66849o or whatever number and these I will make up intelligent2022 Icandive, whatstakingso lonng, Iamlongbuthaveaquestion...blah blah
Yes Nick says allot of the character of management.
Great reporting Danish! Thanks
I will go out and say we have tld by Tuesday Jan 18 2022. If I am wrong I will donate 500 to a gofundme page for gpm. If Iam correct I will donate 1000
I will post the reciept here. Signed Joe (not scotty) Cav
Hi Extrooper, I think main goal of shorts now is to accumulate maximum shares on tld reveal. Thats where the real money is. Say stock is 80 cents and on tld it goes 4 bucks. 5 Banger but then a negative article comes out and stock goes to 2.80 You will get some panic selling at that level. People will take money off the table at 10 banger because they think theyre being prudent.
Retail sells to early and thats when institutions acquire stock.
Little to no stock is trading relative to the float. These shareholders are diamond hands.
This should be the most exciting reveal in my life (cant wait)
I was long Dendreon at 3.50 and it only opened at 7.50 on results. Think it took 2 months to get to 55 and 2 years to get to a buck.
This Nwbo saga is so huge it looks outrageous. Jack in the beanstalk.outrageous. Luckily I been a dreamer all my life and believe good will prevail.
So perhaps when Linda P alluded to waiting for the huge home run she was talking about the Keytruda/ Dcvax combo readout.
When she made that statement it was early in that combo trial so no one was thinking that she was referring to that trial.
Now If you think about it that trial enrolled very quickly and we have heard nothing about it..
If its actually the case that Dcvax and Keytruda have a positive symbiotic relationship then we are golden.
Pfizer can write the press release that Dcvax increases the efficacy of Keytruda but we will know the truth.
Looking forward to that combo trial results...
So on excellent data I see big money opening this up at 2.50 and hold it there first day or 2. Thats the high from over a year ago that some shareholders are wishing they would have done some trading at 2.20 or realistically at 1.80
My thesis is that this short attack on low volume wants to accomplish early profit taking by retail that have been holding for years. From 60 cents its a 4 banger to 2.40. When stock was at 1.50 a 4 banger was 6 bucks.
These guys running this market dont think small. They want to accumulate 150 million shares between 2 and 3 bucks as a start. Best way to acomplish this is starting from a low base.
Furthermore a low starting stock price can delay uplisting and institutional investing for a little longer.
Good luck dreamers and visionaries
Perhaps biocomparable studies will be done with one tumour from a compassionate patient. The tumour will be used to produce vaccine in the lab and in the flasworks device. I am betting hoping the flasworks device produces superior results.
Ocata stem cell therapy was buried Treatment for blindness. Bought out by Astellas
What do we know? Hopefully quite a bit judging the average age of this board.
Heres what I know.
The few people I care about that I suggested they should buy the stock kept asking me if they should buy more when the price was going up.
When the 6 month price decline came about nobody asked if they should buy... only if they should sell.
So this tells me that people in the know realize that the only way to accumulate stock is to keep moving stock price down. This achieves 2 goals. Less buying but more important it will look like a big move up when news is released.
Big money wants to accumulate 100 Million shares at three four five bucks on the iniatial news.
I am betting wherever it opens up at on tld reveal it will drop all day from the high.
Personally I would not sell a share on unblinding knowing how much news is yet to be revealed.
Good luck dreamers and visionaries!
Real life story Hyperopia, thanks for that. I think many of us retail investors discovered this stock looking for a better therapy for cancer for ourselves or loved ones.
Funny how life throws you a curveball. Sometimes surviving the hardest times comes with unexpected rewards down the road.
Good luck dreamers and visionaries.
Looks like they buried the technology
Two statements Linda P said was go big or go home. And perhaps we should wait for the grand slam.
When she said those words I knew we would be waiting another year.
The wait has been escruciating.
But thinking about it, if nwbo announced results a year ago the short attacks would have been relentless. Shorts would have manufactured doubt in regulatory approvoal, manufacturing capibility, floods at Sawston ect
Think about it. If she announced results last year without a journal and we had to wait over a year and a half for approvoal we would have been attacked relentlesly.
Its never been our call on what Linda does because she does what she wants. Yes she believes shes the smartest in the room. She taught the courses in biotech manufacturing. She negotiated trade deals for USA
So I am still all in because this investment is the safest 10 or 100 banger that I believe in.
Best of luck to fellow visionaries and dreamers of a better future.
Yes great read thanks... Sad thing is seeing newbie retail investors panic and believe some of the crap written on these message boards
The most amazing trial ever for heart patients to be be released tomorrow at AHA conference. Heres the abstract before official release
https://eventpilotadmin.com/web/page.php?page=IntHtml&project=AHA21&id=6669
Mesoblast cell therapy trial. 80% reduction in death when cells are given earlier in disease.
The NEJM is supposed to come out with their article right after the conference.
This is probably the blueprint of how our data will be revealed next week.
This is all the cell sector which we are included in.
Big news this weekend and Monday for our sector.!
So I have a theory which I think might have a 40% chance of being correct. I am invested in a few cell therapy companies. Its been no secret that partnership negotiotions have been talked about for years yet no big deal has been done. Also no cell therapy has yet to been approved by fda. Japan is on the verge of big approvoals. Meso was denied for gvhd for kids with amazing efficacy. Cell therapy is so far ahead of current treatments that its a no brainer to approve and bring these therapies to market.
So back to my theory. The partnerships or buyouts are going to happen within weeks or months of first cell therapy deal made.
So for example a big big deal is announced between Novartis and Mesoblast. That sends stock price up of NWBO ATHX and PSTI.
That in turn allows a higher buyout or partnership price of the other cell therapy stocks.
The reality is that all these deals that will be announced were worked on for a year and a half or more.
The big boys already split up and decided who would partner with each company.
So what I am saying is that these big pharma companies may all get together and watch the Godfather and then divide up the territories.
What I know is that allot of investors have been waiting for a big cell therapy buyout or partnership deal. Especially if you look at the dollars being invested in manufacturing bioreactors and more.
My theory of investestment in the cell sector in the last 8 years has been that partnership or buyouts would be done simountanously.
I always believed it could happen at any time because the theraputic benefits of cell therapy was so obvious.
Boy was I nieve.The fact is that big pharma was quite successful in delaying adoption of the new paridigm shift.
All the while the big boys have been slow negotiating with MESO, ATHX, NWBO PSTI and CLBS among other.
Big pharma knew the shift was coming to personalized medicine but the organization was not going to allow any one big pharma to go out and make a deal on its own and destroy the golden goose.
So the first big partnership deal will validate the big deals that are about to happen quickly thereafter.
Novartis just got 20 billion selling there stake in Roche. They have been talking with Mesoblast last 18 months.
I am hoping for a BIG deal there.
I believe it hapens something like this...
Tony from Pfizer you will get the Ards drug from mesoblast and you will have European distribution.
Edward representing the Merck family you will be responsible for distribution of the Atherys stroke thingy drug n North america and Columbia and Peru.
Anyway its time has come for personalized therapy. Lets only use chemo when its a last resort.
As we wait for tld in what is supposed to be a binary event, I want you to take this into consideration.
When big money knows a drug trial failed they run the price up and create hype and interest in the stock. Stock price moves up and positive news articles are written. And all the while these hedge funds are actually taking short positions.
Here is the opposite playing out No news articles to buy the stock. Stock price is going down.. nothing to see here.Attacked on yahoo and other boards.
So my advice is if stock gets to 25 ,35 or more and cnbc is telling you its a buy... thats when you sell??
Some of your position.
I started to research cancer immunotherapy when I was diagnosed with kidney cancer in 2006
invested in dendreon in 2009 at 3.5 bucks. On data release stating they met statistical endpoints stock opened up at 7 bucks. After that I think it took 3 or 4 months to top out at 55 bucks. I sold half my position at 50 and the other half at 30. And yes I got lucky
DNDN eventually went to a buck because it didnt live up to expectations and was not actually grounbeaking results.
So now we are on the eve of data release that compares this new therapy to soc thats been going on for last 30 years.
My real point is that this stock story is bigger than any of the bullcrap fomo stories that have been hyped in the last few years. Crypto fb space travel, amazon delivery uber eats. and on an on
People will pay to live if they can enjoy a good quality of life.
I think most of us would choose a cancer immunotherapy with a 25% chance of cure to chemo treatment where you feel like crap and have to act like your not miserabel.
This whole concept and endeavour is huge beyond belief.
Hi Sojo, my recent thoughts have been that lately the forces against us have been doing whatever they can to go against your chart predictions.
The charts and trends have been falling in line for some years as you have pointed out to us. Your chart reading and techinacal analysis has been spot on.
Now we are on the eve of potential news and volume is low. This is when big money trys to shake out long time retail investors.
All I am saying is that while volume is low thugs will remain in contol.
The crazy thing is that 10 million share day will move the stock big time. And thats less than 1% of outstanding shares.
Thanks for your dedication
I find us in a unique situation with this stock that I have never encountered in biotech. First our market cap is listed at about 1.1 billion and thats on the otc. Fully diluted were probably capitalized at 1.6 billion.
My previous long shot bio bets never had that high market cap.
Second big flag that makes this stock look like it will succeed is there is no hedge funds pumping it up and actually taking short positions because they know trial failed.
You can bet your ann that if this trial failed that big money would be writing articles about the huge chance of success in this trial.
So here we are with crickets on a 1.5 billion mc company.
This is just one other factor pointing to success among so many others.
Hi Skit Reddit is just another social media platform but its not regulated like these pay to play forums
When this stock explodes you wont be able to find a poster you recoginize without allot of scrolling
Good luck
So when initial inflamation looked like tumour growth but it was actually an immune battle and not the tumour growing.
And that was proven because the patients that supposedly progessed were not dying.
Now we have a new trial with an endpoint of pfs at 6 months. So you have to ask yourself what they learned from previous trials that makes them confident that they can use this endpoint.
I think theres new biomarkers available now that can determine if dcvax or dcvax and keytruda is working.
Ahh Jerry welcome to the real world. Sec is a device used by big money to keep down competition.
But you do know that right...
I feel safer after they put Martha Stewart inprison
Inews is owned by Daily Mail Uk
so positive that this article out of uk really talks up DCVax
can someone tell me some good long posters on this board. Thanks