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Sadly.:)
Being a MA based company, he´s got trouble coming.
LR,
I find at times you speak in riddles(sort of), but mostly not.
How shall we take them(the officers) to task?
Ask simple questions w/o accusations, but, do wonder, bewilderedly, why we are where we are?. Only two people can answer that question.
KarinCA,
The case was dismissed after the judge reviewed all of it. Rosen got his "facts" from a hit piece on SA. I suspect Rosen expected the company to settle out of court and didn't care whether or not what he filed was accurate.
I've got to stop reading this board... I keep getting sucked in by need to comment.¨
What should be also be highlighted is that ctix(ipix-today) attempted to counter sue at that time, and failed. Nobody lost anything, other than retail investors.
Sullivan best be on guard.
¨
PP,
Thanks for posting that, I hadn´t seen it before(should have).
Never mind just the estimated trial cost, there´s also alot of other matters to ¨judge¨.
I guess that explains the hiring of Dr. Bertolino and others shortly thereafter.
kfc
Aye, my wheels are spinning in anticipation of any announcement(s), or not.
With the ipix phone too heavy to lift, we´re left to wonder in thought.
What are they doing, what have they done? Nothing but foisted questions (for us) to hoist?
D. Crandall(Hogan Lovetts) comes with admirition and praise. Do wonder if Roger Crandall(MassMutual) is associated in some way?
IDK
ps red sox up 6-1, top of ninth
Pss- modified the 3rd paragraph to end with a ? mark.
Aye, my wheels are spinning in anticipation of any announcement(s), or not.
With the ipix phone too heavy to lift, we´re left to wonder in thought.
What are they doing, what have they done? Nothing but foisted questions (for us) to hoist.
D. Crandall(Hogan Lovetts) comes with admirition and praise. Do wonder if Roger Crandall(MassMutual) is associated in some way?
IDK
ps red sox up 6-1, top of ninth
Dud,
¨another worthless day of disguised Aspire selling - raise gas money for the Leo yacht ride this coming weekend.¨
I trust you meant diesel, not gas(won´t get in to the technicalities) .
¨glad I sold some at .43¨ You certainly seem to like playing with fire. Beginning to think you may have an office at 151-B, or 247-C Cummings Center.
JFC(&,HPR)
LR,
¨Would you expect that that statement contemplated the use of sachets in a Phase 3 trial versus a new Phase 2 trial? BTW,"Sure as hell doesn't mean it doesn't work" seems spot on, but is that the perspective you would expect the FDA to take in terms of clinical trials?¨
Good questions. Is it possible that they run a 3 arm phase 3 trial?
Arm 1- swish and spit, arm 2- B sachets, arm 3- placebo?
Just a thought.
kfc
TIAB,
With headlines like their 5/9/18 concerning B-OM,¨Innovation Pharmaceuticals Concludes Data Analysis of its Phase 2 Clinical Trial for Severe Oral Mucositis in Head and Neck Cancer; Positioning to Fill a Substantial Void in Supportive Cancer Care¨ and this statement from same pr “Given the notable interest from global and specialty pharmaceutical companies that we have received following recent Brilacidin-OM data releases, we continue to carefully assess all of our potential alliance opportunities—toward cementing the best pathway forward,” said Leo Ehrlich, Chief Executive Officer of Innovation Pharmaceuticals. “The expedient advancement of Brilacidin-OM into later clinical development is a priority, as is the broader expansion of the complete Brilacidin Franchise.” leads one to beleive they didn´t lose too much interest.
Hopefully they have drawn up requests for proposals with all with the same scope (per indication) so as to expedite review and reduce alot of questions.
kfc
33 calendar days, 22 working days.
Yup,
Just a little while more.
12 months to the day:http://www.ipharminc.com/press-release/2017/8/28/innovation-pharmaceuticals-completes-full-patient-enrollment-in-phase-2b-study-of-prurisol-for-the-oral-treatment-of-psoriasis
11 months ago:https://investorshub.advfn.com/boards/read_msg.aspx?message_id=135024214
¨A 563 share Trade at .39666. What?¨
Someone´s diaper money?;)
MackG,
¨This statement, and many others like it that attempt to portray IPIX in a negative light, underscores the reality of the IPIX Deep-State, whose sole purpose is to depress the share price and discourage new investors. IMO.¨
Are suggesting new investor´s should take the likes of George´s proclamations as gospel? P alone is worth 15 Billion? How can he state such gibberish when THE RESULTS HAVE NOT BEEN RELEASED(and may not)?
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=128027403
DUD,
We(Massachusetts) rank 18th highest tax burden out of the 50 states, clearly not close to leading the pack. Granted, Taxachusetts has a nice ring when politicians speak, but we´re sandwiched between Nebraska and Arkansas as far as total tax burden is concerned.
https://wallethub.com/edu/states-with-highest-lowest-tax-burden/20494/
TY Karin,
My reply was to George, and I expect he´ll answer.
KFC
G,
Please provide your direct comparison to Brilacidin.
TY,
KFC
Karin,
Thanks for simple and honest reply. I yearn for nothing more than something that #1- benefits society, and #2 benefits my investments with good yields and results, in that order.
I shall never stop looking.
TY,
KFC
When shall it triple?
Thanks georgejjl,
Tis quite apparent at this point in ¨the venture¨, and to astute observers, that you and sox040713(not a New Englander despite his suggested namesake), along with a few others, team together to pollute legitimate conversations(discussions/ arguements). I don´t doubt that sox will precede my post by the time I hit send, or you´ll have a follow-up to this post which I am responding to.
GLTU, you´ll all need it. You´ve taken on the wrong town(City), if Erhlich´s proclomations ring, deceptively, false(deceptive).
KFC
rmzport,
¨I'm guessing BTD within in hours. Leo and team "concluded its review of all data outputs and corresponding analyses" on May 9. Knowing they were going to apply for BTD since Dec, 2017 i would be surprised if Leo took more than a week to file w/ the FDA¨
Clearly your projection is a wee bit out of kilter but, I suppose, means not that it can not be plumbed if he did his job(to file).
GLTA,
KFC
KarinCA,
¨Edit to add... as another poster has pointed out, this article is dealing with radioprotection, not drugs such as Brilacidin. It's not surprise to not see Brilacidin mentioned.¨
Agree, but regardless of the mechanism of action(design), I trust that all those involved with OM research, including ipix, seek a better treatment than what is presently approved and available.
Thanks Empiricist1 for posting that link. I find it informative to compare and assess. Although I may become a bit more disgruntled with each passing day, I do realize patience is a virtue, and trust that the following statement from Dr. Bertolino in the ipix 4/9/18 pr rings true: “Reducing incidence of SOM sets the gold standard and is key to capturing the large HNC market currently lacking any approved drugs. With this new expanded information on the effectiveness of Brilacidin-OM, coupled with our previously reported successful primary results, we think our novel compound continues to raise the bar as the leading SOM drug in development.”, not to mention similiar quotes pertaining to Prurisol for psoriasis.
Competition is good
GLTA,
KFC
p.s- never heard of this company til empicicst1 post. Competition is always good, clearly ipix has more than one competitor in the OM market.
1. EpicentRX team: http://www.epicentrx.com/team-mission/
2. EpicentRX 8/9/18 Science Trends article(including poem, a must read). https://sciencetrends.com/radioprotectors-defensive-weapons-in-the-war-on-cancer/
Epiricist1,
Thanks for the reply. I had not read it (your link did not include the report), so I googled the title included in your post and found it. Its in the link refernced below in case others were also unable to open the link.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918142/
kfc
JTO,
I´m not touting Galera, only comparing them to ipix(who appaears to be floating on water-logged piece of driftwood about to go down-lest they(ipix) very quickly provide starving(from relavent info) shareholder´s a life ring.
Couldn´t find the Galera gc4419 side effects, perhaps you can.
I did find this, and the fda seems to like it so far.
<In addition, patients treated with GC4419 experienced longer delays in the time to onset of oral mucositis, and fewer grade 4 events occurred. The agent was also tolerated and the frequency of treatment-related side effects was comparable across all treatment arms in the trial.
“There are three things about this study that are very important for demonstrating that our technology works,” said Sorensen. “The first is we had a very robust result, highly statistically significant and clinically relevant in the primary endpoint. The second is that all of the secondary endpoints pointed in the same direction, that they were consistent with the primary endpoint. And third is that the intermediate dose, 30 mg, was also intermediate in results between the two arms.”
Sorensen noted these trial results show promise in reducing additional radiation-related toxicities. “This was a demonstration that we could not only selectively reduce the toxicity of radiation, but also preserve the activity of the chemoradiation, in other words, not reduce that against the cancer.”
Therefore, Galera Therapeutics intends to further investigate GC4419 as an agent to treat and reduce, and go after the cancer itself, as well as the side effects, Sorensen said.
“We want to make sure that our plan and our discussion with the FDA results in the most efficient way to get this to patients because after all everything we do is theoretical until we can actually get it to patients, which is what we want to do,” he added.>
It takes a while and as noted, we are not talking about a huge staff. Doing the statistical analyses is easy, mostly automate after it has been entered (in itself not so easy), the rest is not.¨
Apparently it takes much longer than LE advised we loyal investors´ of ctix/ipix. Regarding p2b, they´ve gone from 3q17 to 4q17 to 1q18 to 1st half 18, to 9/30/18. Anyone who´s not a wee bit taken aback and upset is dishonest imo. It implies he doesn´t know what he´s talking about, while his words have killed most investors.
Regarding another ipix venture, oral mucositis, Galera Therapeutics blows ipix out of the water when it comes to execution.
Ph2b OM study:
Galera started 14 months later than ipix and finished 2 months ahead of ipix(ipix was 69% longer)
Galera enrolled 265% more patients than ipix(223 vs 61)
Galera used 281% more sites than ipix(61 vs 16)
Galera received BTD 164 days after primary trial completion vs ipix, 249 days(253 days as of 8/27/18) and counting.
To be noted as why results may have taken longer for ipix OM results- ipix had 2 primary outcome mesures vs 1 by Galera, ipix had 16 secondary outcome measures vs 7 for Galera, Ipix had zero other outcome measures vs 14 for Galera. I won´t attempt to filter them.
Condolences to Pittsburgh & PA. Clearly, many were aware of the breach.
Don´t believe everything you hear(are told). If someone at ipix could just pick up the phone.
No news by 8/31/18, they´ll have asked for it(the onslaught).
petemantx,
Sorry, guess I was not as clear as I intended to be.
My response was primarily about time, why change from ¨swish and spit¨ to sachets if you already possess the cat´s meow for OM?
kfc
JTO,
Correct, probio offered no justification of his/her statement vs LR´s reponse, which did.
kfc
KarinCA,
Largest global psoriasis survey shows 84% of people face discrimination and humiliation because of their skin¨.
Agree 100% and would also put ¨frustration¨ with approved treatments right up there. Vanity does not make the list as far as I´m concerned.
If I had psoriasis, and based upon what I have reviewed as a result of my investment in ipix, I would be all over eli lilly´s Ixekizumab, ph2 results posted below, and hope ipix comes close(lilly´s is injected, ipix is oral- a plus)
https://clinicaltrials.gov/ct2/show/results/NCT01107457?show_locs=Y§=X4301256#othr
¨
Otay is all I can say(reply).
Here Today,
Direct anwers please.
TY,
KFC
Here Today,
Thank you for your response, which in part you state- ¨For those who invest in Bio stocks, they know that Big Pharma's would rather scoop up companies and drug candidates out of a Bankruptcy hearing than to have to partner or buyout. So for Leo to have advanced IPIX's drug pipeline to the point where it currently stands at without taking on Toxic Diluting debt (like companies that take loans at ridiculous share redemption valuations) and to still be under 300million Outstanding shares is a Feat in itself. That's where my faith in him as a money managing CEO comes from. your resposne, in which, in part, you state ¨
I suppose you may be correct. Examples (proof of statement) please.
TY,
KFC
Here Today(i must state, when I hear that, my first thought is ¨gone tomorrow¨),
I left this out of your quote-¨I'm in no rush for a deal. I have faith in Leo and how he has handled and been frugal in his spending here¨
How much time are you willing to give him, and where does your faith in Leo derive from? Clearly, your faith in him is not founded in his ability to meet timelines, is it?
Here´s wishing a bit of luck to all longs(not much else to add).
Nothing Again (Pharmaceutical?). Did they change their name again?
BooDog,
¨As for brilacidin, it's been 104 days since the May 9 PR concluding data. Not 249 days as Kfc mentioned, though he did say primary.¨
You are correct, I said 249 days since primary(completion). Regarding data, Galera received BTD 73 days after dara release vs ipix, 104 days and counting.
Empiricst1,
¨It takes a while and as noted, we are not talking about a huge staff. Doing the statistical analyses is easy, mostly automate after it has been entered (in itself not so easy), the rest is not.¨
Apparently it takes much longer than LE advised we loyal investors´ of ctix/ipix. Regarding p2b, they´ve gone from 3q17 to 4q17 to 1q18 to 1st half 18, to 9/30/18. Anyone who´s not a wee bit taken aback and upset is dishonest imo. It implies he doesn´t know what he´s talking about, while his words have killed most investors.
Regarding another ipix venture, oral mucositis, Galera Therapeutics blows ipix out of the water when it comes to execution.
Ph2b OM study:
Galera started 14 months later than ipix and finished 2 months ahead of ipix(ipix was 69% longer)
Galera enrolled 265% more patients than ipix(223 vs 61)
Galera used 281% more sites than ipix(61 vs 16)
Galera received BTD 164 days after primary trial completion vs ipix, 249 days and counting.
To be noted as why results may have taken longer for ipix OM results- ipix had 2 primary outcome mesures vs 1 by Galera, ipix had 16 secondary outcome measures vs 7 for Galera, Ipix had zero other outcome measures vs 14 for Galera. I won´t attempt to filter them.
kfc
¨As discussed earlier in the week, the lease automatically extends on the 30th September, unless one party or the other informs that it won’t be extending.¨
You are correct, and the auther of quoted info was LR, often referred as Loan Ranger(a frequent poster on this board).
You, LilKahuna, left out the remaining portion of his /her quote. Are YOU willing to provide it, or, must I?
petemantx,
Pardon my ignorance, but it appears you´re talking to yourself(did you intend to respond to someone directly?)
kfc
KarinCA,
¨There isn't much substantive to say until the company releases more information. Until then, all we can do is sell, hold, or buy more and wait.¨
Very well stated and, I believe, your post is a paraphrase of tb12nh´s intended message(can´t speak for him, but the way I interpreted it). Glad the first response was deleted, as I consider tb12nh an honest poster.
I was going to not so nicely reference tumbleweeds and thorny trousers while replying to the deleted message. I prefer your response better(reminds me of a qoute i´ve heard¨be breif, be bright, be gone¨).
ty
Echo20,
¨Maybe management is certain of their products at this point.
Nyuk-nyuk-nyuk, maybe...