JTO,
I´m not touting Galera, only comparing them to ipix(who appaears to be floating on water-logged piece of driftwood about to go down-lest they(ipix) very quickly provide starving(from relavent info) shareholder´s a life ring.
Couldn´t find the Galera gc4419 side effects, perhaps you can.
I did find this, and the fda seems to like it so far.
<In addition, patients treated with GC4419 experienced longer delays in the time to onset of oral mucositis, and fewer grade 4 events occurred. The agent was also tolerated and the frequency of treatment-related side effects was comparable across all treatment arms in the trial.
“There are three things about this study that are very important for demonstrating that our technology works,” said Sorensen. “The first is we had a very robust result, highly statistically significant and clinically relevant in the primary endpoint. The second is that all of the secondary endpoints pointed in the same direction, that they were consistent with the primary endpoint. And third is that the intermediate dose, 30 mg, was also intermediate in results between the two arms.”
Sorensen noted these trial results show promise in reducing additional radiation-related toxicities. “This was a demonstration that we could not only selectively reduce the toxicity of radiation, but also preserve the activity of the chemoradiation, in other words, not reduce that against the cancer.”
Therefore, Galera Therapeutics intends to further investigate GC4419 as an agent to treat and reduce, and go after the cancer itself, as well as the side effects, Sorensen said.
“We want to make sure that our plan and our discussion with the FDA results in the most efficient way to get this to patients because after all everything we do is theoretical until we can actually get it to patients, which is what we want to do,” he added.>
