Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
hope is not playing the piano or painting pictures or playing golf.
hope is not how we have gone froma market cap of $20 Millinto $260 Million..
People getting better is what drives Anavex..
2 years of continuing Data from 2a PART B..2 more years!
hope is NOT what is driving Anavex..REALITY is
2 Important notes:
1. Adverse Affects were labeled as the same as one would find for a Phase 1 Healthy Volunteer Group..THAT by itself is UNBELIEVABLE!
2. the good Dr. gave himself a hefty cash pay raise..where is he going to get the cash to pay for that raise?
My guess is..the good Dr. is getting his hefty pay raise from the $$$$ that will be covering the cost of the A2-73 Phase 3 Trials..
Exactly
great post ipulator
thank you
Hess..
You missed the ongoing Anti-Depression Testing..
I think they may have INTERIM ADCS-ADL for 38 Weeks and 52 Weeks..maybe..
Also...do PK Tests continue? or are we done with PK until Phase 2/3?
ok..so how many patients are in or out or back in or replaced..
kind of hard to do the math based on Poster..looking like 27-28 Patients left..I don't know how they treat the response rate regarding people who dropped out..do they include them in %'s or not? I assume they do..
i was thinking an 85% effect rate..that seems like it's going to be high..
Also..since positve mention of high cognitive response rate at 5 weeks..
the 12 and 26 weeks estimates may need to be lowered from 6 Points up to
say 5 points up..Still Rock Star Status..I am duly impressed that a patient suffering cancer and who begins Chemotherapy LOVES A2-73 so much that they continue taking A2-73 during Chemo. That is belief! They KNOW what is at stake! Cancer isn't the ONLY KILLER stalking them. Hope this patient kicks Cancer's derriere!
here some more gleaned gems:
"May have a broader scope in addressing diesasES!" Again MULTIPLE IND.
-16 Positive unexpected Therapeutic response Events- Don't know HOW these Events are accounted for? Was it 16 Patients that enjoyed one or more of these events, was it 16 different types of Benefits Enjoyed by different patients...Mood Improvement, Family Engagement..Activities(AKA - LIFE!)
So the reason this sticks out for Caretakers..is because..this is DIFFERENT FROM WHAT CARETAKERS EXPERIENCE with other AD Patients..THUS..the UNEXPECTED in Statement Title..
or NOT LOSING THEM IN THE FIRST PLACE!
to the Heroes of the first Trial of A2-73 that have left due to
whatever reason, i say, THANK YOU! You are a hero to me and to everyone who desires an end to this wicked disease. I Pray fo ryou and your family, that perhaps your health will hold and an adjunct to A2-73 may be found or another succesful route. the Love of the Eteranl Creator awaits all who believe and love..May peace find you in this world and eternal joy in the next. Life is short, Love hard
They list out all the other observed POSITIVES in Poster..
her e is the one I like the most..\
more interaction with family..
Short that blackhearts
50 MG is Maximum Tolerated DOSE! FANTASTIC!
That is what I got out of all of this..
50MG a DAY keeps AD AWAY!
Major Tom to Gorund Control!
i appreciate Miss Australia's posting, both her good and her not so good. Such is life. honesty is always appreciated, sometimes not welcome, but always appreciated. She and her family are in my prayers. I look forward to meeting her someday maybe, and I consider all the Trial Participants and their family's heroes. God Bless Miss Australia!
how could one argue..i will not..Come on ANAVEX!
Yes! Sunday i think we just get overwhelmed with Proof Positive that Wednesdays Data is NOT FLUKE! IRREFUTABLE..But Sunday DATA will still give insight for Wednesday's Data....The Question is ..
will the data be enough? My answer as usual...
It already IS! Don't understand what everyone else is waiting for..
the Fat Lady to Sing? Cute girl on the Piano's not enough? A pretty oil painting? Tough crowd..TUFF!
F1 ..will try to find time tonight and have tomorrow
it is not just "cognitive" it is overall QUALITY of life..Anti-Depressive-Anti-Anxiety- Better sleep, less stress..BBB..bam..Honestly..
Xena IMO due to the longer time of ONSET of AD people and so many past failures the community NOW treats potential treatments like they have ALL DAY..Alzheimers is CANCER of the Identity! Everyday, more of WHO YOU ARE IS LOST FOREVER! Chances are Anavex is just going to STOP THE THIEF..maybe A2-73 will help get back some of the stolen memories..
We have to TREAT Alzheimers with same urgency and FDA response as if ti were A DEADLY CANCER..If ANAVEX proves to be 50% EFFECTIVE with NO SIDE EFFECTS..we need BTD and COMPASSIONATE USE..Let the Patients DYING take the RISKS..For goodness sakes..
Looking for anywhere OVER 68 on ADCS-ADL is a HOME RUN..ANAVEX NOW..BTD..You be the Blind Mouse PLACEBO but GIVE ME THE DRUG!
Normal Score on Alzheimers patient at 6 months would be 60 or BELOW..
NO PLACEBO EFFECT AFTER 12 WEEKS..NONE..Get ready for the GREATEST WEEKEND EVER!
PLEX..i posted earlier how I derived at +6 ..YES it is a GOOD NUMBER..
I think it might be low..here is how I came up with from earlier post:
I changed some of the wording but left conclusions the same..
it is simple math and deductive reasoning..
at least 10%(I actually ASSUME a HIGHER NOMBER) of 32n study has if not fully recovered, close to and since the ADCS-ADL test is quite basic..their improvement on their score should be substantial.
The % of overall effected is 80% ..at least..probably higher since we KNOW that we have PK Effect SO the low responding 3 mg dosage is eliminated and a more positive effect from higher & longer dosage..
75% up 5pts 69 X .75 of 32 =24= 1656
10% up 10pt 74 X 4 = 296
start at 64 pts Educated Guess for ADCS-ADL at 26 WEEKS = 69.71 pts
UP 5.71 PTS..
Patients with ZERO HELP..probably even with Aricept Down 4-5 Points at 6 months..or ..linear decline from Trial start..usual progression of AD..
59pts would be average ADCS-ADL score
it is not complicated..made very few assumptions that do not make sense based on past reports and announcements..
what do YOU THINK this ADCS-ADL number or a very like number will do
to Anavex? Especailly when ALL THE OTHER TESTS back up COGNITIVE IMPROVEMENTS ..
predicting +6 on ADCS-ADL and over 80% of population positively effected.
Other Data to CONFIRM this result. Normal Patients without or really WITH any treatment will be DOWN on ADCS-ADL Test 4-6 Points at 6 months.
Demand Breakthrough! Demand IMMEDIATE FDA ACCESS through ANY PROGRAM!
COMING SOON:
Anavex NOW!
As the Scientific Medical types go once again into the scrum of despair fro Placebo and Blinds, some of us will begin a very different approach to A2-73 Approval. anavex now...have not decided the time or resources to expend yet..but i believe the upcoming Data will Demand immediate A2-73 Action.
Demand it...
You are probably correct in that a groundswell for ANavex will not occur UNTIL the DATA is PUBLIC. I can not call a Congressman for 11 out of 14 without MORE DATA to back it up. We shall soon have our DATA, then "let slip the dogs of War"..
The Dye is not yet cast..but soon my friends..soon
i don't understand how we are not through $30PPS or higher..
loss for words..i thought people could read..oh well ..soon enough
so..the Shorts keep shorting ANavex AFTER they announce they have the Drug to Treat Alzheimers. Truly it is unnerving. Would BP destroy the only treatment for Alzheimers to keep people sick and that they may make profit?
That i even ask the question makes me sick
thanks Jimmy! fun song
somone post 6-31 Short Sales at 4.2 MIllion shares.
That makes me feel better..
we don't have to find that many buyers to move this stock past $14 to
new all time highs..we have 4.2 million shares just waiting to buy back in..Thank You Shortie Mc Short Short and Corey and Fool and AF..and all you haters of the only treatment for AD..because you all are not very nice.
good call Xena..probably exactl what they doing..
If you have a relevant interest competing or otherwise, which is likely to effect your opinion, it would be a moral certitude that it should be disclosed. Legal is another issue.
the day after YAHOO Message Boards destroyed, the Motley Fool article shows up..bet Attorney ROSEN could find some clients to sue Motley Fool..Article had NO DISCLOSURE about Motley's BIOGEN POSITION..FRAUD
Great Reminder! I assume the FDA, since they are guiding ongoing Phase 2/3 design, already has 31 Week Data. I assume $$$ for Phase 2/3 are already arranged/available because of the good Dr.'s new compensation plan. The good Dr. doesn't get that raise without imminent success, period.
Does any long doubt the data? than why on earth would you risk trading this stock? by trading your stock you aid Adam Fuerstien the Motley Fool Martin Shrkeili Corey Renauer Biogen...There si ZERO CHANCE that A2-73 Data is NOT OUTSTANDING, which means Anavex is worth BILLIONS..Every second you are not an owner of Anavex you risk so much and aid her enemies.
ACCUMULATE
are people getting better? because No ONE eles is making Alzheimer Patients get better. Anavex is more than HOPE it is a REALITY of SURVIVAL. Not ONLY do we have ENOUGH DATA to Move Forward, we have ENOUGH DATA for Compassionate Care Use, Breakthrough Designation..WE DO HAVE ENOUGH and WE wil HAVE EVEN MORE COME NEXT WEEK! and oh yeah..The FDA ALREADY HAS THIS DATA! Wait until Gabriel's Trumpet Sounds at AAIC and EVERYONE DEMANDS ANAVEX..Because ONCE the general POPULATION SEES THE SATA..
WHAT DO YOU THINK THEY ARE GOING TO SAY?..THINK ABOUT IT>>
The GENERAL POPULATION is NOT going to say, we need a PLACEBO..They are NOT going to say BLINDFOLD a patient..They are going to SAY...FIVE US ANAVEX NOW! Why wouldn't they? Why would not you give it to them? If 80% of a Dying Cancer study(Over 30 patients) so 24 Human Beings Show Remission and teh Cnacer STOPS and they LIVE..THAT IS ENOUGH..if there are ZERO SAFETY CONCERNS..This started as a 26 WEEK Study(desinged with FDA GUIDELINES)..
We Have teh DATA, We have the Drug. Anavex is the HERO!
new deceiptful Motley Fool article by Corey Renauer feind(forgot the r)
Fools must they think we are..Can not wait for the good Dr to cost them billions..and their pathetic short cabal..disgusting
would not be surprised to see another PR for unrelated topic..PK, Rett Syndrome, Depression, etc..Thu or Fri..also next week..think News will hit beofre AAIC..do not need any news AFTER AAIC..(maybe BP License Deal) because the DATA is SO GOOD , Anavex will "Drop The Mic" and not need any more news other than DATA..everyone will be in AWE and Disbelief.
WE HAVE THE DRUG
It WORKS
God has a tremendous sense of humor! AF just experienced it. Arrogance and pride, how long will eternity be for the poor lad? pretty doggone long. perhaps AF should move along as he has zero crediblity, zero.
lets'go even deeper into the Anavex Solution..What IF, Anavex is actually keeping people alive longer as they are happier and healthier..
Truly we have a Blessed Blockbuster of a Drug..
The 6 month study should show the Depression Analysis as well..
it is simple math and deductive reasoning..
at least 10% of 32n study has if not fully recovered, close to and since the ADCS-ADL test is quite basic..their improvement on their score should be substantial.
The % of overall effected is 80% ..at least..probably higher since no 3 mg dosage and longer dosage..
75% up 5pts 69 X .75 of 32 =24= 1656
10% up 10pt 74 X 4 = 296
start at 64 pts Educated Guess for ADCS-ADL at 26 WEEKS = 69.71 pts
UP 5.71 PTS..
Patients with ZERO HELP..probably even with Aricept Down 4-5 Points at 6 months..or ..linear decline from Trial start..usual progression of AD..
59pts would be average ADCS-ADL score
it is not complicated..made very few assumptions that do not make sense based on past reports and announcements..
what do YOU THINK this ADCS-ADL number or a very like number will do
to Anavex? Especailly when ALL THE OTHER TESTS back up COGNITIVE IMPROVEMENTS ..
TITLE: Company that Treats Alzheimers WORTH BILLIONS
Anavex Title: We have the drug that works to treat alzheimers!
How much is Anavex Worth?
See Title!
Get it
they didn't "walk it back"! They confirmed it in another pr!
The lying shorts, created ..LIES ..
They NEVER WALKED ANYTHING BACK..
it is the presentation Tom..they will release it..
just think of all the other FUN DATA we shall see!
Depression..etc..
it's ok Ziggy..that is why I porvide the Simple Titling Service for the Hard of Reading: It Works. You are welcome