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Hi Xena,
I want Anavex to remain Publicly traded..
just want postiive buyers to hold and accumulate through
Phase 3 completion. I think they can hold 80% or MORE of
35 Million shares for under $7 share..
All under 5% and undeclared..we don't actually go private..
Godly families and Institutions just Privately hold shares in a Publicly traded co. trying to treat Alzheimers until Phase 3 is complete..
1. BP wants to DELAY or Destroy Anavex..Threat to TRILLIONS of wealth!
2. Hedge Funds through AXON are now Players in ALZHEIMERS GAME.
3. Motley Fool is Invested in Biogen.(has failed Alzheimer rug in Dev.)
4. Easy to scare retail when such high % of Co. shares(95%?) are Traded and not tightly held by family, founder, employees.
5. Guaranteed Money..They WIN..Sell enough to scare people..BUYERS don;t ORGANIZE a BUY POINT..the Short Cabal has a good thing going..It's working and they are getting rich.
6. Anavex could destroy so much of how things are structured..the powers that be almost willing to do anything to stop it..
The Short Cabal has and is an ORganization with Billions of
dollars of Private Investor's dollars STOLEN..
Today..Whacky or not..
The Publicly Private Club
is going to start the wheels in motion..
of righting that ship..
Accmulate Today..and until ..and Hard
Under $200,000,000 be a buyer....
join the
Whacky Publicly Private Club of Anavex!
Consider this an Invitation..
Let's find 100 American families, of grace, wealth and faith in God..
(Institutions work as well)
to take Anavex Publicly Private. Not to worry about Price, not to worry about Motley Fool. just to commit to buy a # of Shares or a $$ amount and to PUT AWAY as an INVESTMENT TO TREAT ALZHEIMERS..
And these Families Hold these TRUSTED SHARES Until Phase 3 is complete.
Then they have done their job of helping a young company figure out whether or not it has the new well tolerated Monotherapy for Alzheimers, A2-73.
A Company Publicly for sale for UNDER $200,000,000 which may have a HUMANE Treatment for a Disease Estimated to have millions of sufferers and be worth over $10 BILLION to aid those sufferers..ANNUALLY..
Every Believer try to find a Family or Institution to put ANavex away until the end of Phase 3...or NEXT YEAR! That is not an Eternal time frame for goodness sakes..not a LONG time to HOLD A STOCK..
This one holding may come to Equal the other 99% of that Institutions holdings..No one may afford to lose anything..and yet we do everyday..becasue sometimes losing is the cost of WINNING..
Let's take Anavex Privately Public or make it Publicly Private.
I am buying more today. I will trade as I see fit, either trying to accumulate more or even leaving altogether..as My family is not wealthy and may only risk so much.(but I will review and begin to take delivery of some of my shares).but there are Estates, Trust, Institutions , People who are VERY, VERY successful..that may PUT AWAY Millions of $$ worth of this Company...Honorably trying to Treat Alzheimers..JUST BUY EVERYTHING UNDER $200,000,000..
The Short Cabal..Will Knock it back UNDER..(we know theri game)
and THEN JUST BUY MORE..
The Short CABAL attacks over $200,000,000 so The Publicly Private Club might even be able to accumulate MORE Than 35,000,000 shares.
Their Science DEMANDS a PHASE 3 NOW..
the FDA is GUIDING OUR PHASE 3 Design..
Let's take Anavex Publicly Private.
ACCUMULATE.
yes..Retail can not compete against the Shrot Cabal .
the SEC is supposed to protect..but BP..has everyone Bought and SOLD..
I say the SHAREHOLDERS ..TAKE ANAVEX Privately Public..let's just commit to buying shares through Phase 3 Completion Until we Own 35 Million..
Retail could do that..All the Docs, the Families..
If we just found 10 wealthy Families that put away 1 million shares each and 20 Families that put away 500,000 shares each..that is half the company..
We need BELIEVERS..the good Dr. deserves some BELIEVERS..
Amen
WHY is Anavex worth Billions? Why is it only a Fraction of it's value?
Well..let me give you a quick Factual Explanation of WHY Anavex is worth
$500,000,000 right NOW! Really it's over a BILLION..but HEY..let's keep what the SHORT CABAL has been able to do to the Market Value, as a wicked reminder of the frailties of our current capitalist system..Where the BIG BOYS can SUCK THE LIFE and MONEY right out from the COmpetitors by hiring
Shiseter Law Firms, Shisster Advisor Firms(Own BIOGEN), Shiester Doctors and Sheister hedge Funds((OWN AXON)which compete with your drug)..
So now we have estableished the REASON and MOTIVATION of WHY our Company is undervalued..but now let me STEEL YOURSELF as to WHY Believers JUST ACCUMULATE and ACCUMULATE..
The Short Cabal will allow Anavex to trade over $200 Million because teh Short Cabal knows that OVER $200 Million RETAIL can not support the MV and FEAR is TOO EASY ..and SHORTS >>tehy do riskless trades..
DON'T FEAR because THEY HAVE ENOUGH MONEY TO MANIPULATE THE MARKET...
They SELL SO MUCH STOCK SHORT>>Spread BAD STORIES...Half TRUTHS..Grease teh Wrong Wheels/..and they ALL KNOW IT"S COMING AND PARTICIPATE..
IT's LIKE THE RED HEADED STEP CHILD..And teh SEC DOES NOTHING! SICK.
I digress.. Back to the Value of ANVEX and WHY YOU SHOULD ACCUMULATE..
First..what has Anavex accomplished..
Original Timeline of Phase 2a Part A and PART B- Complete and succesful.
1. Safety : Any reactions seen as same as healthey control group.
I don't want to get into this too much, but Aricept has some SICK SIDE EFFECTS ..how it ever got apporved is a testament to how miserable ALzheimres is and hwo wonderful, what soon will be, the NEW SOC , A2-73 IS...
Phase 3 is demanded and expected. TEH FDA IS GUIDING IT"S DESIGN..HELLOOOOO!.WHo cares HOW IT SI PAID FOR..SOMEONE will PAY UP and UP for it..one way or the other and We will benefit for it, by having CASH and a Phase 3 to look forward to..Both of which will be positives and move the MV UP! Oh and ALL the OTHER IND's..\
The SAFETY and LACK OF NEGATIVE SIDE EFFECTS OF A2-73 MAKES ANAVEX A BILLION DOLLAR COMPANY RIGHT NOW..RIGHT NOW!
I just am so insanely excited by all that Anavex has accomplished with so little..and proved and has in the works..all of it having value in the hundreds of millions..but add it up..and it's BBBBillions..
.ACCUMULATE my friends..BELIEVE
http://www.forbes.com/sites/matthewherper/2013/08/11/how-the-staggering-cost-of-inventing-new-drugs-is-shaping-the-future-of-medicine/#8d0f6036bfcb
COST/VALUE OF NEW DRUG ..$5 BILLION ..Are YOU KIDDING ME?
What are WE DOING ANAVEX SHAREHOLDERS? Drop Kick the TROLLS and
ACCUMULATE!
another sick Motley Fool HIT PIECE on ANVEX..
I would not be surprised if the SHORT CABAL destroying MV
for ANAVEX is RUN DIRECTLY OUT OF Motley FOOL'S HEAD OFFICE!
Corey Renauer and the other SICK analysts at Motley Fool with their
half truths and INTERSET IN BIOGEN (different Alzheimer Co)
trying to destroy Anavex..PUKES!
WE ARE ANAVEX! LET"S OWN ALL 35 MILLION or 40 MILLION SHARES..
WHO CARES..You are talking UNDER $200,000,000..
THAT IS NOTHING..I am buying more tomorrow..and will buy more as money allows..I will accumulate as much as I may..
and SOON..the Motley Fool will be exposed as part of the SHORT CABAL..
SOON..Mayve someone will leak some emails between
AF, CR and Shrkeili..who knows..
Don't get Renauered!
oh good Dr...the time for being nice is over..
We need to help Alzheimer's Patients , we are their Shepherds..
let us defend them from the wolves of the Short Cabal and the Fool's in the Motley Hell.
the pay off for alzheimers and other CNS and other Diseases dwarfs "psoraisis" and the data does support for ALL patients moving forward..
the pooled data is not telling us the whole story as the Dr's are saying there was not a decline..so..
Not only is a Phase 3 justified, it is demanded..and IF, YOU really were here to help stop Alzheimers..ASAP..you would not be throwing a wet blanket on 7 people ..you would be rejoicing like the rest of us..that for over 20% of the patients of a SUCCESFUL SAFETY Trial, a curative response was observed!
And YET It2211, in MY SOLE Magnificience
I have managed to do the IMPOSSIBLE!
Voila! $500,000,000!
It was not even hard to do:
Cost of getting Drug into Humans in a Phase 3 Trial:
$360,000,000.
Success at SAFETY of DRUG:
$200,000,000
Value of TIME:
We already have this DONE:
Priceless:
I conservatively reduced my Valuation Estimate by $60,000,000 and did not throw in another $500,000,000 of Market Comparative Valuation (SEE AXON)
because I want to try in the realm of Weak Minds and their ability to Comprehend.
F1- I am NOT an INVESTMENT nor LIFE advisor are you?
I will say a few things to help you with your point:
Old sayings are wise sayings: Never invest more than you may afford to lose: You don't know what you don't know. There is no such thing as a sure thing. One of my favorites: In Moderato.
This is what I would tell them.
I have more confidence in Anavex and the good Dr than I have ever had about any stock. I sleep at night dreaming about what Indication A2-73 might help next! I am not worried about dilution as I will let the good Dr worry about funding Phase 3 for Rett SYndrome and Alzheimers and Depression and Anxiety and Insomnia and..well you get the Pic.
I do worry about the wellness of the patients, both for them and their families and for safety/efficacy. In my dreams, I see holding Alzheimers at Bay and running out the clock..I think now Anavex will probably need some help, maybe Taurx maybe something else..who knows. Maybe Not though..
I would love to see INTERIM Data on the Magnificent 7 at 52 WEEKS..If you know what I mean..I don't think I will be as blindly positive on the A2-73 potetnial results..but it's hard.
As far as my Valuation, Predictions, Estimations, Precognifications, Determinations and Prognofifications..If you don't enjoy them for what they are, than you should simply not read my posts.
Wat are they? A positively tinged, lifelong Devoted (trying to avoid Demoted) Christian's optimist renderings of foretelling the unknown. I don't know why I feel serenity and joy as an owner of Anavex, but I do.
It would be unfair to expect you to have read such an outpouring without giving some semblance of a direct answer, for I am neither a Progressive nor a Democrat,so..
The $500,000,000 is a combination valuation of Comparative Research Costs to have a Drug ANY DRUG ready for a Phase 3..Much Less a Phase 3 with over a $10 BILLION annual market..Our current Valuation is a JOKE.
It's like stealing. SOrry, but that is TRUTH to me.
Regarding appropriate actions to try and take advantage of said Valuation:
Review: OLD SAYINGS.
Some KEYS I use to determine Stock Cred:
1: CEO is he a greedy , lying tool? NO..Good Guy, Intelligent. BAM!
2. Are insiders buying , or selling? ONLY BUYING that we know.
3. Immediate and ongoing Prospects of Positive Developments: VERY HIGH
4. Calculating Biggest Risk: Failure of A2-73 Safety and immediate results on companiy's future. Have other drugs , but would result in dilution and lower valuation. Can you survive that?
5. Calculating Financial Needs- Dilution and Success..Here we have a KNOWN need of tens of Millions of Dollars for Phase 3..and only $12 Million in Bank. So ..Somewhere something has to give to accomplish a Phase 3..Right? You don't know what you don't know..
Also..A pHase 3 is going to generate so MUCH excitement that ANY Dilution is going to quickly recovered by the POSSIBLITY that MOnothereapy of A2-73 may be the key to Alzheimer SOC..
See I didn't even say Reversal or Curative..I am so proud of myself!
I wish I could paint or play a piano..Ah! But I do play GOLF!
A Round it is!
YOU MUST BE KIDDING? $100 Million is NOTHING!
BP Spits that out with Shrimp Guts everyday..
Anavex has Research Value ALONE of MORE than $500,000,000 ....
Any License Deal is in the BILLIONS with Hundreds of MILLIONS upfront to anavex
DID YOU see the Montherapy Data?
LOOKS like 100 % of One Arm Monotherapy saw Curative Effect over 6 months..
when they ALL would have/should have fallen by 4-6 Points..
$100,000 ,000 for a Business that is worth 10's of billions EVERY YEAR?
will not let loose how I realy feel..
i think this is why the good Dr got a raise..
this is incredible data at 6 months..
if 20% of cancer trial found remission and ALL of them were in one ARM or 100% of one ARM were experiencing remission..there would be a LITTLE EXCITEMENT!
Think about this with me sports fans..
INTERIM 12 Weeks shjowed 11 of 14 Patients going from 64 to 67..Pooled..
These would have been the FIRST Entrants into the Study..they would also be the first Interim at 38 WEEKS and by now even 52 WEEKS..
Guess What..based on Data at 26 Weeks..we may surmise that most of the MONOTHERAPY Patients are in the FIRST GROUP..
ANavex ONCE AGAIN probably has the stratified One YEar Efficacy Data on the 7 Monotherapy Patients..
and the good Dr just got a raise..
exactly steaming eagle! the good Dr THOUGHT he had great Data!
Why? He can see the SDCS-AL chart..oh wait maybe he thought we would all focus on the YELLOW LINE Going UP of Montotherapy..or MME Scores UP in Monotherapy and that WE would be able to put 2 and 2 together..
the good Dr just doesn;t realize how slow we are..
We are coming around..
i appreciate you ziggy..even if we don't always see eye to eye ..in the end
the goal is available treatments to AD sufferers that work..ASAP..I still believe hard in Anavex..just wishing that line would have been a little less vertically challenged on the Aricept & A2-73 group..
Ziggy..
I understood what you meant..
did you read my whole post..
A Study is a Study..unless of course it is called an
ADAPTIVE STUDY..then everything you said holds true but
the parameters, methods and controls may all be adjusted
to what ay be hypothesixd to offer teh ost insight into a postiive outcome..
So..by allowing or changing or adapting the Monotherapy versus Aricept
we ALLOW for MORE DATA NOW..NONE of the Numbers of Patients in any grouping are going to be large enough to determine EFFICACAL DATA, but they may give us great insight into Structuring Phase 3!
What if 10 of the remaining 20 A2-73 and Aricept Patients are asked to
discontinue Aricept? You can't make them..I would not think..but you could ASK..THen our Data in 5 Months would include MOno Therapy with A2-73..
If THERE numbers went UP like the current 7 Monotherapy Numbers..and there were no ILL SIDE EFFECTS from Dropping Aricept..THEN we would have BETTER SCIENCE with which to design Phase 3..Yes?
There is no blind, no placebo..so we SEE THE DATA IN REAL TIME..ALL THE DATA ..except PK/PD..
A true Anavex Long is Accumulating and has been accumulating over the past 3 years..but the Analogy si not without merit. If this Data had been bad, the longs would have been the second to bail and this stock would not have stopped at $3.5..Right? It was not the Shorts who stopeed and supported Anavex, but the Longs! Why? BESIDES ALL the OTHER Reasons to SUPPORT ANAVEX up to $500,000,000 in Market Cap Before it goes to BILLIONS..
There were some REAL GOLD NUGGETS in this Data..
But for the 7 Pateints or OVER 20% of n=27 Population that experienced a rising ADCS-ADL and MME Score at 6 months..well let us just say..that this hot potato cools off QUICKLY with our soon to be announced Phase 3 for ALzheimers and/or with a BP License Deal.and/or a Phase 3 for Rett Syndrome and/or a Michael J FOx PK Announcement or..well YOU get the Picture.
Cools off fast..7 patients on Monotherapy went up at 6 months ..Aricept might be counteracting the A2-73 Action or like Taurx thinks..Cleaning out the Medicine..now ..let's break out those Tea Leaves Bros?
unethical? hm..
I might agree that as far as Science is concerned the greater the Number and length of time of knowledge regarding a drug(s) and interaction is helpful. SO..recording patients that have been on Aricept and A2-73 that STOP taking Aricept will give us INVALUABLE DAT over the next two years as to the consequences of this action.
We will need to know this sooner or later as so many patients are on Aricept now, When we begin Phase 3 , many may want to join Trial but Stop Taking Aricept..(Do you think that should just be another ARM in Phase 3?)
Will Patients on MOnotherapy A2-73 react DIFFERNETLY if they have NEVER TAKEN Aricept or just if they STOP taking Aricept?
By Adapting the PART B NOW for those who CHOOSE so, we begin to have Data for whether or not a separate ARM is recommended.
Unethical.could be considered letting people suffer for the sake of science when they don't have to..
But your points are not without merit or hyperbole
JB..I did not understand that as I thought the PK at 5 Weeks was designed to give Patients a better Dosing..I thought I read that somewhere ..but maybe I just assumed. Again..for me ..knowing this Makes the Data even stronger..I would have not had as high expectations if I know the continuing Patient's Dosage was not upped to at least 30 Mg or 14 Mg...
it is an adaptive trial..so some things have changed..it is not unreasonable to think Dosage would be changed to a level where PK was known to show effect.
why didn't they Optiize the dosage in PART B?
You mean there are still people only getting 10Mg?
come on Anavex..this is an ADAPTIVE TRIAL..
Would think offering ALL PARTICIPANTS the OPTION
to go MONOTHERAPY ..would be reasonable at this point..
I don't want to post Aricept Side Effects everyday..but
they are not pretty..
Great Find BA, looks like PK at every phase..
Does anyone follow Depression and comparative results to the Depression test scale?
Failure to Launch:One Reason to Stay
You MUST do a Phase 3 to Confirm/Deny Monotherapy Data.
and THEY WILL!
well said apost..
like you don'e want to see people getting better?
a world without hope is a better place?
WTH
Thank you Dr. M..I creid when I saw those videos..
I bet all of them were Mono Therapy A2-73 ONLY.
would like to KNOW that..just a guess..
Look..This stock is risky as heck..99% FAIL RATE for Alzheimers.
If you don't KNOW THAT than how did you get MONEY?
Anavex is DOING ALL THIS ON A SHOE STRING..they have accomplished with
20,000,000 in capital what BP takes 500,000,000 to do..
Our company is still worth Billion..just going to take another 6 months.
Maybe..unless they already have a BP that can read..
Bunch of crying wonkers..Biotek and Alzheimers ..
and you still have half your money?
Phase 3 is coming and coming soon..
bs..do we only get PK one time? do we need it for future studies or
just for Safety and MTD? which we already have..
you are not alone..
still letting the dust settle..
AnavexNow based upon this data would need to be a MonoTherapy
I think..Taurx should be allowed as a MonoTherapy as well if it's safety profile atches A2-73. Where we find success let's exploit it for Goodness Sakes..
does 7 people make a whole arguent ..no..but if 7 out of 7 Patients taking A2-73 ALL EXPERIENCED PK and Success..that is
100%..
Phase 3 CAN NOT GET HERE FAST ENOUGH..
just hit the shorts with a Rett Syndrome right and Phase 3 left..
New SOC, A2-73 Monotherapy..Phase 3 -6 months begin 2017..
Bam..
Would like ALL Patients to go Monotherapy in current trial that want to..
and ADAPT Trial results for those that go Mono A2-73..
7 patients Monotherapy on A2-73..DID GREAT!
20% of Population OFF THE CHARTS!..
Right?
what would they say about the good Dr. then?
OBVIOUSLY they noticed the difference..
so..the WHOLE POINT of this study was to show SAFETY, PK, Max.Tolerated Dosage, 5Omg and maybe get a sneak peak at EFFICACY.
The good Dr. accomplished ALL of the ABOVE!
WE accomplished ALL OF THE ABOVE! A+ Right? I mean our Max Dosage could have been too little..
We could have had Aricept's Saftery Profile..(you ever seen that?)
AND we KNOW we have PK..We have ACTION!
ALL this so that if Patients WERE getting better, than Phase 3 would be successful. Do you know that the Fail Rate in Phase 3 is OFF the Chart.
Talk to Biogen if you want to hear about Failure in Phase 3..OUCH.
I think and I am with you..that what they found, is exactly as you say.
Follow the Yellow Brick Road. Monotherapy with A2-73 so that it may someday be the new Aricept and when drugs using different mechanisms come along, THEY may do studies with A2-73.
Look, I honestly think Anavex thought this data was positive.
When I crunched the numbers for ADCS-ADL anything around 70 at 26 weeks was a home run! Looks like the average with ALL N=27 is around 63..those with Aricept 62?
so at 5 weeks we had 64 average for group at 26 weeks we had 63..it is stable..
Taking the ADCS-ADL Scale from 64 at 5 Weeks ..the USUAL Alzheimer Patient 5 Months later would probably have scored below 60, as regression for Alzheimer Patients with Mild to moderate Alzheimers is liners with ADCS-ADl a litle less than a point a month. 10-12 Points over a year down.
and EVERYONE on the Yellow Brick Road Group did OBVIOUSLY BETTER..
I don't think the beginning score of 70 was accurate and I have posted why. (How do you drop 6 Points in 5 weeks? Not really possible in Mild to Moderate Ad- I don't believe the starting number 70 was accurate)
The Phase 3 in my opinion should focus on Monotherapy and have an arm of patients that do not want to give up Aricept.
If I am a patient and looking at these numbers..it is hard to consider not going Mono. They should GIVE THE Continuing PART B Patients that CHOICE and then MONITOR the results.(this will not be the last time I make this suggestion)
I was looking for a continuation of the positive trending of Interim 12 weeks...it didn't happen..i think the good Dr recognized this Data at 26 weeks and did not want to pump up the stock by releasing full 12 week data..remember this is an OPEN TRIAL ..they have DATA for many patients for over 52 WEEKS. It is Obvious that the good Dr. can not win..so I understand WHY we did not see any Interim Data at this phase.
So time to get over disappointment. Re Check the Positives and Negatives.
Are people getting better? YES ..we know at least 10% got a LOT BETTER!
Looks like those ONLY taking A2-73 are STAYING BETTER LONGER.
The Mono-Therapy pool is about 20% of Phase 2a..They should be more than 50% of Phase 3..
Let's go already with Phase 3..
The good Dr.needs to earn his pay raise that WE GAVE HIM..
Come on!
i don't know about patent issues..but
doubt that A2-73 as a Mono Therapy HURTS Anavex's Patent rights.
and with these chart readings of A2 + Aricept..
who cares about Patent rights..Aricept has a LOT of Side Effects as well..
One less pill to pop..
thanks for ginseng heads up..
like the take on Data read..
The NUMBER ONE reading i get from recent Studies of
A2-73 and DROP ARICEPT and go Mono!
Follow the Yellow Brick Road
KMBJN..a reasonable request..will do..
also..will review rest of your post..
will try to respond tomorrow am..
i still think there is no way a deal is not done..
they have had this data and FDA working to arrange Phase 3..
they would have wanted a Cost Partner to be a part of outline and discussion..
yes frrol..as I thought about and researched this ADCS-ADL Base line ..
the Phase 2a PART A Base for ADcS-ADL, at the beginning of the test ..the caregivers and patients may not really know what to expect..so when they give their answers to the ADCS-ADL test prior to the beginning of the Trial..they are probably not as cognizant of the items in question and guess more than they should..After they take the first ADCS-ADL Exam..they pay more attention to what it is actually happening..
I maintain the 64 Base at the end of PART B as the proper place to start..
really 24 days of dosing..on and off..the Actual ADCS-ADL was probably even BELOW 64 IMO..
and IF you start there..THAN we have a HOME RUN through 6 Months..
so frustrating. Really wish they would have just stuck with PART B Baseline..there is no way that 70 ADCS-ADL to start test was accurate..IMO
wish they would have left ADCS baseline from PART B as starting point. a little bitter as if you start their 70 at 26 weeks is a homerun for the monotherapy patients(those patients NOT TAKING ARICEPT)
i have put in a call to Ir at Anavex which I rarely do
regarding the ADCS-ADl numbers
and why PART B BASE score for ADCS-ADL was 64 Points vs
the number used in their latest presentation at 0 weeks of 70 Points?
I am a LONG TERM HUGE FAN and BELIEVER in Anavex..and am in accumulation.
ACCUMULATE
NO SHAME in ACCUMULATING SHARES :
PART DEUX
really I am going to keep this reply regarding the
second Poster and why it SCREAMS accumulate SIMPLE:
Follow the Yellow Brick Road.
Ovwr 20% of P=N 32 did exceptionally well even at 6 months
on the NEW SOC.
ACCUMULATE
Ever seen the side effects of Aricept?
Some side effects of Aricept are malaise, appetite loss, weight loss, sleep problems (insomnia), muscle cramps, tiredness, drowsiness, dizziness,
weakness, shakiness (tremor), itchy skin, nausea, vomiting, or diarrhea.
oh but WAIT..I am not done YET!
Serious side effects of Aricept include painful urination, seizures, chest pain, and GI symptoms of tarry or bloody stools and vomiting blood or material that resembles "coffee grounds".
Why there is NO SHAME in ACCUMULATING SHARES
PART1
Let's start with Poster 1:
The MTD determination from the present Phase 2a study, allows for
a Phase 2/3 study to be conducted according to a double-blind
design including placebo. To complete the design of a future study,
population PK data (and the evaluation of inter-patient variability) are
necessary in order to compute the patients’ sample size and to
achieve conclusions associated with a given statistical power. This is
currently in progress.
• ANAVEX 2-73 may have a broader scope in addressing diseases by
virtue of both its molecular biology and the favorable safety profile
observed thus far. Estimating MTD is a prerequisite for the
progression of ANAVEX 2-73 towa
rds further clinical trial
the number of side benefits:
16 Events reported with the Preferred Term of ‘Therapeutic Response
Unexpected’. A sample of verbatim terms reported include:
ü Improved Engagement with Family/Friends
ü Improvement in Mood
ü Increased Independent Activity
ü Feeling Happier
ü Improved Alertness
ü Better Coordination
ü Better Coping
SAFETY:
96% of all AEs were mild or moderate and 83% events are
recovered/resolved. AE profile similar to that of healthy volunteer Phase
1 data (Schindler 2
So ACCUMULATE based on THIS if nothing else..
Blzzy..nothing unreasonable about anything you said..
Legal is running the show at Anavex as far as what gets announced and when..
I am still very positive, but disappointed at the breakdown at 26 weeks..
AD is some wicked wicked stuff..
Surely Anavex will have other positive announcements shortly..
the good Dr.'s salary increase amounted to an additional $25,000 per month..(frmom $200k to $500k annual..
i am betting we see where that money is coming from shortly ..
or PK or Epilepsy or Depression or Rett Syndrome..
Anavex is Dramatically undervalued..but I would have to say..
not as dramatically undervalued as I had hoped..
there are going to be some big swing days ahead..
also..
the Phase 3 is going to happen..with FDA Guidance..
by new Salary structure with the good Dr...one way or another the financing is already in place..