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I don't know if they'd do compassionate use here, but take a look at this and perhaps you can get it requested for your friend.
https://www.globenewswire.com/news-release/2020/04/07/2012754/0/en/Pluristem-Reports-Preliminary-Data-from-its-COVID-19-Compassionate-Use-Program-Treating-Seven-Patients-with-Acute-Respiratory-Failure.html
Right now all the testing is in Israel and Germany, but the drug is in use here in other trials, so if authorized it should be available.
Gary
I would hope that between Israel and Germany they've expanded those getting PLX-PAD to at least 100 patients, then we'd have evidence that's undeniable. I'd also like to see a secondary group that are very congested, but not yet on a ventilator get the drug, and see if far fewer move to the ventilator, and if recovery appears accelerated.
If we now assume 20 million shares are outstanding, our market cap is still under $100 million, if trials confirm initial indications, it should be over ten times that.
Gary
Thanks, I skimmed it quickly and clearly missed it.
Gary
I don't see us on this list, did I miss it somewhere, or does the company need to do something to call attention to it.
https://milkeninstitute.org/sites/default/files/2020-04/Covid19%20Tracker%20NEW4-3-20-2.pdf
Clearly there is a tremendous amount of work going on for this, I would think if many got together it could be done quicker in a Manhattan Project sort of environment.
Gary
When it comes to a buyout, I believe there is a price at which anything is for sale. In the case of PCTL, I believe it's certainly somewhere in double digit billions, or perhaps high single digits.
Others have pointed out that others make our fluid, it's true. What's unique about what PCTL's doing is giving anyone wanting to make the fluid themselves the right to do so easily with readily available salt and water. In short, with little concern anyone can have an unlimited supply in not just the fluid, but a tracking system that tells them where it's been used, where it may need to be used, and if a portable device is being used to apply it, it's fresh enough to be effective. This is not simply handing the customer a product, it's handing them a system.
The deeper you dig into the company the greater you see it's potential can be. Certainly you don't get a $10 billion bid on a company with a market cap in the millions, but build that market cap up to a billion or more, than you might build interest in a buyout, and if you had a few bidders, it wouldn't take long to bid it up to $10 billion, or more. In that a $1 billion market cap represents just under $2 a share, I believe it's possible this year.
Gary
I show NWBO closing up $.0025, no big deal, but better than a loss. I really don't think we'll have a substantial movement in any direction until we get something of substance from the company. For now, the company may be up, or down with the general market, which is largely concerned with coronavirus, but once it's somewhat resolved, and when life returns to something more normal, I believe we'll see it move on its own.
Gary
I support the idea of trying something, rather than nothing, but I believe that Fauci and others are not that impressed with results with that drug. I believe PLX-PAD which is derived from placental stem cells and is being tried in Israel and Germany would be a much better choice. In it's patents pnemonia is clearly something it's intended for, though clinical trials to date, which are up to Phase 3, are for other things. The Chinese have indicated some success with placental stem cells.
PLSI has the patents for the 3-D bioreactor that will create 20,000 doses of this, or other, placental based drugs from a single placenta. I believe they have a substantial quantity of the drug stored cryogenically and they've made it available for compassionate use.
I believe there are other similar drugs also being tried, but clearly PSTI can produce more of it with their process. Others much more medically knowledgeable than me believe that two doses would be needed per patient, so potentially a single placenta could treat 10,000 patients with pneumonia whether it's caused by coronavirus, or other causes.
Clearly, the FDA hasn't studied this either, I'm waiting to hear what's happened in Israel and/or Germany, but once again it will be a small trial. I'm of the belief that the results may be far better than the marginal results seen with hydroxychloroquine. I believe that Trump is pushing the first thing he learned might have benefits rather than researching all the possibilities. I also understand the Chinese are saying they'll have a vaccine by Summer, if that's the case, can't we trust that as something we could use here, and reach an agreement with them to mass produce it.
We were ill prepared for the pandemic for many reasons, but clearly one of the biggest was our insistance on developing our own test, instead of working with the worlds nations to use, or improve on, what was being used in other parts of the world. Of course we lost the bubble some time before that when Trump eliminated the pandemic staff that was encouraging study of pandemics around the world. I'm sorry if this offends those who believe Trump is a hero in this matter, but if he is, can someone please explain to me how we lead the world in numbers of patients, and deaths.
Gary
I don't believe you're seeing crowds at hospital entrances, etc because that's not where coronavirus patients are entering, and non patients aren't permitted to come in to even visit. The ER associated with the hospital is more likely to be where the action is occurring, where people are being tested, evaluated, and the worst being hospitalized whether they come in by ambulance, or walk in.
As a patient at City of Hope they've made it clear that should I come in for an appointment, I cannot come in with anyone else, I'll be screened at the enterance, and if I'm having fever or other symptoms be directed to a different enterance where I'll be tested. To date, my appointment has been delayed a month, and I won't be surprised if it's delay beyond that.
I'm only suggesting that you'll not see chaos at hospital enterances, etc, the chaos is on the hospital floors where patients are stacked up to or beyond their capacity. Where you see lines, it's generally for testing, or where food banks are distributing food. This is real, but if you wish to take a drive, the road have the lightest traffic you'll ever see, at least here in L.A.
Gary
Nothing moves a stock like earnings. Sure, we know the delinquent quarter and annual report won't have them. But I believe the Annual Report can speak about current conditions up to the day it's issued, and I believe it can state that after the first quarter, which will still have a loss, later quarters all anticipate a profit.
Show profits and this is not a penny stock. Likewise, if consensus earnings are established, even if it's a substantial loss, if you beat the consensus, it's amazing you the share price is lifted.
I don't know that we have analysts establishing a consensus for our earnings, but if we do, I'd like to know what they are. If we start to show earnings, Analysts will follow. Before we know it, Analysts will be recommending the company to many of their investors, but not while it's selling for just a few pennies. Give it time and you'll be thrilled about your investment in this company.
Gary
If we get positive news in coronavirus, no controller will be able to hold down our share price. Without it, we'll be just fine as the CLI and other trials come to fruition and demonstrate the benefits we know are occurring. The FDA trial process is frustrating, they don't want to believe what they can see in front of their eyes, they want a pile of data that they can spend 6 months or more examining to say, yes the improvement is worthy of approval. Hopefully something less will be considered for coronavirus, at least in terms of permitting unlimited compassionate use, or right to try, if early data supports it.
We have fewer than 20 million shares outstanding. If we are credited with contributing to the condition of people with coronavirus, what is a fair market cap for the stock. I believe it will take us to over $1 billion. Approval for CLI or other applications should do as much or more, but they're some time away, coronavirus benefits would do it in a manner of hours.
Gary
I don't question the legality of what the company's doing, but I hope that as it grows it will move to get on at least the OTC exchange here in the U.S.
When I first bought through Fidelity I was assured the value of my VXLLF would be equal to VXL.CA, so I haven't worried about it. Of course it's always adjusted to currency fluxuations.
Gary
I only believe there is one reason not to unblind, that being they've not yet completely settled on an SAP that all 4 regulators agree on. Beyond that, any other reason has little, or no validity.
Of course it's very possible it's been agreed to and as we spend time speculating they're gathering information from all clinical sites. They could easily be hung up by just a few patients believed to still be alive that they're attempting to track down. In an interim look, calling a patient LTFU is no big thing, but when gathering up the final data, I believe they do not wish to have anyone in that catagory, even if they 5 years or more into the trial.
We're now at the point where even the last patient to enter the trial if currently alive would be near 4.5 years since beginning the trial, by far most of the living are beyond 5 years, and many probably beyond 6 or 7 years. I don't know how many are alive, but with the SOC it would probably be less than 15, so I believe we'll demonstrate a tremendous improvement on the SOC. Have improvements been made over the years in the trial that effect what the SOC is, we know they have surgically, and some of the later entrants in the trial may have benefitted from this as well, but still the benefits of the drug should be clear.
Gary
I must be honest, I'm holding my stock, but I'm paying little attention to what's happening here because of the company's decision not to report. I can understand their reason's why, but until something official comes from them, it's all speculation as to what they are, or aren't doing.
Years ago I had a stock that was delinquent reports for over a year and suddenly came to life with filing multiple reports finally coming current. When they did, it was to sell the corporate shell. Had I been smart I'd have gotten out when it went up a bit, but it wasn't worth much, so I held and it's hardly done a thing, but continues trading. My point is that companies can come back from the dead, and it could happen here.
I may look in occasionally, but will hardly look at everyones posts. Perhaps when coronavirus is no longer a major concern things will be different for this, and many other companies, and normal life will return to the world.
Gary
Any thoughts on the company moving off the grey market. I believe the share price would meet OTC requirements, but I'm unsure if they meet all such requirements. While they probably could go on the Pinks as well, I'm of the belief that it's hardly better than the grey market. The OTC should be the next step, and when the price meets requirements for other exchanges the move to one of those exchanges. By the way, most people think of the Nasdaq, but I believe the AMEX only requires a $1 price is a reasonable step up that could be achieved far quicker with no consideration of a reverse split which I would hate to see.
In reality, if our vaccine truly proved effective for coronavirus, and was in some way determined superior to others in development, a price in excess of $4 could come quickly as well. I suspect such a determination would result in either a partnership for it's development, or a buyout of either the entire company, or the product.
I certainly agree with all who find that getting information about the company is rather like pulling teeth, but many biotechs are no different. The grey market might limit it a little more, but the fact that it's listed in Canada should provide roughly the same information as what's required by our SEC.
Gary
Gary
Our of curiosity, I used Amazon to look for electrostatic sprayers and saw everything from hand pumped sprayers to powder coating devices using that term, including a lot of electric sprayers. I believe that few of these were truly electrostatic sprayers, I suspect the devices that powder coat would be. Does anyone here know of a small, readily available device that would work in our homes, or small offices if we could get the fluid to spray.
I know the shelf life of our product isn't that great, but if in a sealed container it's good for a few weeks or more. If an inexpensive device for spraying it was available I believe many would purchase the device and use the product during the time it's viable. While products like bleach are generally available, no one would want to mist bleach all over a home, office, or other public establishment. Our product can be used this way, the question is, is there a reasonably price product that can effectively use it.
Personally, I do have an air compressor, they really aren't very expensive for a small one, if the best device involve the use of such a compressor I believe it would be something worthy of consideration.
Gary
Snow,
Thats true of most things it's on, but not everything. It's been found that non-porous surfaces like metal it can last for over 10 days. I believe it was found on the ship that had numerous people with it over two weeks later. Without mitagation it's a very nasty problem.
We try to sanitize or not handle practically everything we receive. Anything on cardboard, paper, etc is supposed to be fine in under a day, so things like mail are just set aside for a day, washing our hands after taking them in, likewise packages delivered to te house.
For a place like a hospital, where patients are known to have it, or a market, drugstore, etc a device like our electrostatic sprayer should be able to sanitize things quite well, but while the pandemic is ongoing they should be used frequently. The good thing is they can be safely used with people present.
Gary
I agree that's what it should be about, the problem is that drug companies who wish to be paid for what they're providing must provide information about what the actual cost of production is. Companies refuse to divulge that information, so they either don't participate, or they give their drug away. A better way needs to be found to pay these companies without forcing them to do what they're completely unwilling to do.
PSTI may have millions of doses available, I don't know, but if they do, I'd like to see the Govt. say, let us buy 100K doses for $1 billion, a price that should be below what their retail price will be, but sufficient to make them whole for making the drug. If we need more, we will purchase more on the same terms. Of course the same terms should be available to Govts. around the world.
Now is not the time for negotiations over what price is fair to save a life, if the drug works, enough should be paid to give the company value, but the key is getting it to patients ASAP. As I see it, every patient on a ventilator plus those the doctors believe could require a ventilator in days should get the drug, if 100K doses isn't sufficient, do it again immediately.
Gary
I believe much of the problem has to do with people justifying their scientific viewpoint of how things should be done. It's very rare that the FDA will see excellent results being achieved and stop a trial and just approve a drug. It goes against everything they stand for.
Our drugs often spend over a decade in development. If benefits were clear in Phase 1/2 you could make them available at some price, where virtually all who received them were considered an additional trial, call it Phase 4 or whatever. That would bring the process down to a couple years, and save hundreds of millions spent in drug development, but their could be some problems, and all who opted for the drug would have to waive their right to take actions against the developer, or the FDA.
Gary
Spider,
While I agree with what you're saying, if we can prove that PLX-PAD works now, while I'd love to see it save a lot of lives, that can only happen if it becomes available in a matter of weeks. Until a vaccine that's effective is developed this will still be a big problem. If it's validated now, in the roughly November time frame where it may start to reappear, perhaps we can greatly limit it's impact by making it generally available for pneumonia patients.
Frankly, I believe pneumonia could be a far greater market than any of the other diseases they've targeted to date. I believe that all forms of pneumonia may benefit from our drugs, not just coronavirus based. Someone with medical knowledge believe that just two doses would be all that would be required. No doubt this won't be cheap, but it will be far cheaper then treating CLI or other diseases that take multiple applications in many places.
Gary
I agree with your valuation, but for sales to be substantial things have to happen quickly if you've seen the curves. Here's a link:
https://covid19.healthdata.org/projections
The point I'm getting at is that by July, things are practically down to nothing. A lot of people will be dead before then, but my point is that to save the lives, this needs to be in the hospitals worldwide in the next few weeks, not in clinical trials. If the outcome in Israel and Germany is so shocking that no one can deny the benefits, perhaps that could happen, but generally the medical community insists on more proof, by the time that occurs, this crisis will be over.
Don't get me wrong, a cure for pneumonia can bring a $100 price by itself, even if the benefit's not seen until more trials are run. I'd like to see lives saved now, and if the early patients show a major improvement, I think they should get it to patients on ventilators, and ideally before they're that advanced, and hopefully avoid the ventilators.
Gary
I know little about Cellularity, as I understand it, we have far greater manufacturing capability, but I'd like to know if the product they're using is already in the clinic for something else, and if so, how far advanced.
In that both of our products are in Phase 3 Trials they've clearly proven themselves safe, and have efficacy worthy of running Phase 3 Trials. I believe that should put us in the lead, even if they're first to dose in the U.S. We're dosing in Israel, and may be in Germany, or will be soon.
If you look at the curves, by mid April we'll be near the peak in most of the forecast curves, basically from what I've seen by June the numbers really come down substantially. If we really want to cut the number of deaths, if initial trials look good, we need to get the worlds govts. to go for treatment with it by May. Here's a link to the best data I've seen for the U.S.
https://covid19.healthdata.org/projections
Our drug won't prevent getting infected with the disease, but if it's effective it can greatly reduce the deaths, and should greatly diminish the need to put people on regulators.
Gary
I wasn't invested then and know nothing about past problems. I'm sure you're essentially correct. If the share price goes dramatically higher on initial news of efficacy in coronavirus, I would have no qualms about the company offering some share to bring in substantial money.
We currently have under 20 million shares outstanding. Solid news should make the company worthy of at least a half billion, but I believe a billion dollar market cap. If the O/S grows to 25 million, that's a $40 price for a billion dollar market cap, frankly if PLX-PAD were adopted for use in pneumonia, I believe the market cap would be well over $10 billion, even if it wasn't given until a patient was thought to need hospital care.
So many diseases ultimately kill when in a weakened state people get pneumonia. Common flu typically kills tens to hundreds of thousands annually, only about .1% of all who get the disease, but still a lot of people who'd survive if the pneumonia were cured.
Let's see what the evidence shows when we get data on many people who've taken the drug.
Gary
In reality, I don't believe most hospitals, etc would choose to sanitize what's intended to be a disposable mask if substantial disposable masks are available at fair prices. Currently people are paying several dollars for something that should be priced at pennies, and will return to pennies when it's not in short supply.
Preventing infections in all sorts of places should have greater value than sanitizing, and then sharing, what are essentially paper masks.
Personally I went to Amazon and purchased cloth masks that have built in replaceable filters. They're selling for what people are spending for a single disposable N-95 mask, they're not quite N-95, but they're far better than folding a scarf.
Gary
I can understand sanitizing agricultural products on harvesting them, but I'm wondering if they have recidual protection for the time they spend in shipment, or on a market shelf. As I understand the coronavirus, on hard surfaces it can live for days, but on softer surfaces, it's less time, I suspect that most vegatables, fruit, etc would be considered softer surfaces, so any virus from harvest ought to be dead by the time it reaches the market.
The market, on the other hand, may have customer with the virus that could get on produce, perhaps it should be routinely sanitized. We make a point of sanitizing what we purchase or have delivered if it's something we want to use immediately, on the other hand we leave it in the garage for at least a day if we don't.
Gary
Personally I'd like to know how many are still alive, the status of the SAP, and I'd like to know if they have a target date for submitting a BLA for the trial, something that's not on your list.
I'm not a great believer in asking questions intended to embarrass management.
Gary
It seems to me that if this works they'll know it in a week or less, why wait for 30 to 60 days.
We're now approaching a week since our first 3 patients were dosed in Israel, by this time I would expect them to know if these people have improved, or not. As I remember it, all 3 patients are already on ventilators, they may be in medically induced comas, if they're treated like most here who are that advanced are. If the drug has worked, I would expect them to be off the ventilator by now, and perhaps even discharged from the hospital. Of course this is JMHO, I have no medical knowledge that the drug should work that quickly. I certainly welcome the thoughts of those who have such medical experience.
Gary
What's the saddest thing to me is that we had people in a pandemics group who predicted this, and they were working with other countries on how to deal with it, until they were fired. It wouldn't have prevented it from happening, but had they been listened to, and remained on the job, we, and perhaps much of the rest of the world would have been much better prepared.
I don't know that a great deal more preparation would have changed how we needed to handle it, but rather it would have lowered the numbers who'll be infected, and die substantially. This is a very contageous disease, but if we knew who had it and maintained proper isolation, it could have been resolved much quicker. As is, I'm hoping that football will be played this fall.
Gary
What's the saddest thing to me is that we had people in a pandemics group who predicted this, and they were working with other countries on how to deal with it, until they were fired. It wouldn't have prevented it from happening, but had they been listened to, and remained on the job, we, and perhaps much of the rest of the world would have been much better prepared.
I don't know that a great deal more preparation would have changed how we needed to handle it, but rather it would have lowered the numbers who'll be infected, and die substantially. This is a very contageous disease, but if we knew who had it and maintained proper isolation, it could have been resolved much quicker. As is, I'm hoping that football will be played this fall.
Gary
For all the theorists on Dr. Duffy, here's the ultimate conspiracy theory. It all began over a dozen years ago when Merck spoke with NWBO management about what they were doing. Essentially they began discussions on what they were doing, and Merck said, you prove it works and is approvable, and we'll buy your company once you prove it to us by trial. They agreed that a fair price would be something over $20 billion.
Time passes, the trial evolves, and approaching the finish line Merck says, we'll keep our end of the bargain, but we need to see how you're doing, and assist you in getting the trial properly evaluated, so we want Dr. Duffy to work with you in dealing with the regulators.
Now Merck's been satisfied, Dr. Duffy has returned, the top line data will be released, the price will move up dramatically, and when the time is right, Merck will step in, perhaps with a partnership at first to build the price higher, but eventually they'll purchase the company.
This is clearly a fiction, but no more so than some of the speculation that others are suggesting about Dr. Duffy's role. We really will never know precisely why Dr. Duffy did what he did, but we know one thing, Merck knows more about what NWBO is doing than any of the other BP's.
Gary
Congrats Captain,
My youngest daughter felt terrible about a week ago, thought she had it, but is feeling much better, and not tested. Frankly I wish we knew one way or the other, but I suspect we won't until some day she has a blood sample taken that will tell if she ever had it.
The stories about people who're sick being refused tests is a sad commentary on where we are. The Federal Govt. makes it sound like we're swimming in tests, and likewise there are plenty of machines that can process them in 15 mibnutes, yet people keep being denied the kit, or when they finally get one it takes a week or more to get results.
I don't doubt that eventually the 15 or less minute test will be available most everywhere, what's sad is with planning ahead it could have been available even before cases were even seen in the U.S. as it was available elsewhere. Perhaps the test developed here is better, but they could have improved on the foreign versions by last December or January if the Govt. had pushed for it.
Gary
In traveling to Japan nearly a half century ago I saw where people wore masks to prevent spreading disease when they were fighting a cold or the flu, it's nothing new. The difference with coronavirus is, many carry it and are infectious without having any sign they have it. That suggests that we all should wear masks if we're going out in public.
I previously wore a mask after stem cells for leukemia, I purchase washable masks that had replaceable filters. Those masks are still available on Amazon, I've ordered more for all the family. Unfortunately, they may be a month from being delivered, but I suspect we won't be free to go out prior to then anyway. Such masks may not be as great as what they need in the hospital, but they're far better than a scarf, etc.
I believe that when blood testing is more commonly preformed many of us who never suspected we had coronavirus will be found to have had it. If that's the case, hopefully it will give us some immunity to getting it again. It could be a year or more before the scientists can honestly estimate how many were really infected, and of course if the number infected is much higher than estimated, the percentage who died will come down. What's important is that even if the death percentage was no greater than the normal flu, this flu appears to be far more infectious, and thats the greatest threat.
I don't doubt that in a month or two sufficient disposable masks will be available for all who want to use them. When I got my washable mask I showed it to my Dr. at City of Hope and he thought it was probably better than the disposable masks available to all patients there. I believe they're an alternative we all should look at.
Gary
I believe the reality is, we'll never know for certain what Duffy's actions were based on. We can speculate all we want, even if Merck does buy into NWBO or buy them out, we can't be certain it was because of Duffy's involvement.
Is it possible that Merck has been interested in what NWBO's been doing from it's beginnings, sure, anything is possible, it's also possible that other companies are also interested. My point is, we really don't know, and we never will.
I still believe we'll be learning something prior to the annual meeting, and whatever we learn about may be discussed at the meeting.
Gary
If you read their recent letter, I believe they're doing both. They indicated that installing units in hospitals in all the chaos isn't happening, but they continue to build them.
As I gather it, they have some much bigger units intended for mass production of the fluids, they're keeping them running full time, I don't know that they're building more of the massive sized units.
It will probably be two months or more before we'll be on the down side of the peaks in most States, perhaps at that time new hospital installations will be able to get started as they ease restrictions on traveling. I frankly believe that we'll be living very differently until we feel we're protected either by a vaccine, or have drugs that greatly improve the treatment, so it's not such a threat to all of us.
I hope I'm wrong, but I really wonder when we'll be able to feel safe about being in a room full of people, or eating in a crowded restaurant. It may be much longer than most think, and if that's the case, I believe the only way many businesses will survive is if debt is simply forgiven, or to put it another way, all are made whole by the Govt. essentially paying all the bills while businesses were closed, or the Govt. paying the difference for places that stayed open but clearly revenue was substantially diminished. It's a nightmare, but without such action it's doubtful that employment will return to prior levels for years.
Gary
I think we all need to think about what would cause a trading halt. A few that I can think of would be:
An order, or commitment by the U.K. to put units in all it'e hospitals.
The U.S. Govt. making a major order to equip U.S. Navy ships.
The VA determining to put units in all its hospitals.
There are many others you can name that would bring huge orders to PCTL and would be game changers and that's the sort of thing that causes a trading halt based on an imbalance of orders.
Gary
The worldwide count of people infected with coronavirus is now over a million, I suspect that for each person tested positive there are ten or more who've not been tested. It's possible we're approaching 100 million, and a billion or more before this is over is certainly possible.
Assuming a blood test will show if you ever had it, years from now we may learn that the numbers went to billions, or more.
Of course knowing that more people have it, and are cured, will actually result in dropping the percentage of those who pass away, but clearly this is still far more deadly than the common flu. Hopefully PSTI will prove it's drug works with pneumonia, and that will cut the deaths in all sorts of pneumonia's, so all the percentages may go down in time.
Gary
I certainly can understand why we've had the delays, now he's made if official as to when we should expect the reports and I believe this should be acceptable to shareholders. Frankly, I wish Fidelity and others who're balking at purchasing the stock would back off, but doubt they will.
April 15th isn't that far away, normally I'd be working on my taxes by now, but like everything else, it can be put off a bit unless I get ambitious.
I'm really wondering if we'll see the opening game of the baseball season before August, but if we do, it should mean that football can open on schedule. As a Ram's fan I'd love to see them in their new stadium, if it can be completed in time with the coronavirus problems they're experiencing. I won't be in the stands if it's done, but will enjoy seeing games from there nonetheless. Perhaps they should talk to PCTL about how to sanitize their stadium once it's built.
I suspect when somewhat normal life returns, we'll all be wearing masks when in public, except when eating, which may be awkward, but better than not eating out at all.
Gary
While I'd certainly like to hear what's happened to the first 3 to receive PLX-PAD, if we don't, but instead hear that several more are getting the drug, I would take that as being equally positive. It would also be positive to hear that German dosing is starting.
It's really frustrating to think that we may have the answer to a worldwide problem, but advancement in treatment moves so slowly because of the intention of the intend of doing things in a clinical way. If it were up to me, compassionate use should make drugs like ours available to Doctors and patients wanting to give it a try, not 3 people, or even dozens, if hundreds want it, they should get it, and each of them should report results. Not as clear as a clinical trial, but if hundreds of critically ill patients try the drug, many of them already on, or about to be put on ventilators, and if many of this group improve, eventually leave the hospital, I believe we're looking at success.
I know that worldwide they're looking for tens of thousands or more ventilators, yet listening to what the normal prognoses is, most who go on the ventilators won't recover. Certainly some people are saved by them, but the greater majority don't. Our drug could be a game changer, but only if we can get it to these people.
Gary
I certainly can't say when it will happen, but our CEO has certainly been willing to speak about what the company is doing on a blog, and I believe he'll do it again after the financials are filed, that will give him the opportunity to put whatever the news in the financials are behind them, and discuss the direction for the future.
Based on his last webcast, March was to be a profitable month, and I believe that April initiates a profitable quarter. How profitable, that's the question. I believe they're selling a lot of their liquid products at a substantial profit, the question is, how many of their machines are they making, and are they being purchased, leased, or are they putting them into their inventory. Depending on the answer, I believe our current quarterly profit could be as high as double, or even triple digit millions, to as low as hundreds, or even tens of thousands of dollars, quite a spread. Until more definition is provided by the company, we really don't know.
Frankly, I don't believe that many profitable companies remain on the Pinks very long. Certainly they can move up to the OTC, and that may happen once the financials are filed, but the major exchanges are a little further away. The Nasdaq is generally considered the next step, but it requires a $4 share price, but I believe the AMEX may still require $1, and that's far more doable once we have a few profitable quarters.
As for the current price, I don't worry about it, let's get the current earnings report out of the way and allow our CEO to discuss them, and discuss the future, then we can see what direction the stock is headed for.
Gary
Sorry, but I take a long term view, and I still believe that's very positive. I got in when it was sub penny, so I still have a nice profit, but I see dollar potential, so I won't be out for a dime, or even a quarter.
Historically it's Institutions that make the most money with stocks moving from pennies to multiple dollars. Small investors make tremendous percentage gains, but if this stock goes to $5 you can bet the majority will be Institutionally owned.
I'll remain an owner, but at $5 if I wished I could borrow hundreds of thousands on margin loan, it's not my plan, but it's nice to know it's possible. I don't have a huge position, but at $5 something like a new Tesla would cost just a small percentage of my shares. I cannot tell you that will happen this year, or next, but I believe the potential is there.
Gary
I certainly wasn't looking forward to this, but I have seen it play out in another company which traded for awell over a year before suddenly producing all sorts of prior quarterly reports. Unfortunately while that company did come back into compliance, it was primarily to sell the stock shell, and the company they sold to went nowhere with it. My point is, they can come through it and it is possible to come out on the other side.
In the meanwhile, the stock will continue to trade, largely based on what people believe is happening. While I certainly hope they'll still do the trial with people with psoriasis or other skin diseases, I don't know that we'll be notified that they are. If they have actions on their patents it's doubtful that they'll say so, but people researching the patent sites may find such action is occurring. If I remember correctly, in the other company the CEO would on occasions take phone calls from investors, so news of the calls were discussed.
If in fact positive things are occurring in spite of the lack of news, when the time is right they'll come current, and we all may be pleasently surprised.
Gary