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That's for the clarification. I hope you know that I was just ribbing you. I actually believe we have several options down the road. I think EMA approval will happen first, sometime before end of 2017.
In any event, I am here until the eventual buyout in '18 or '19. The longer it takes the greater the price. I hope.
You promised! Stay positive my friend! Don't give up unto 9/1/17. :)
I don't want to burst anyone's bubble but a partnership is still a ways off!
Wait Easymoney! Don't we have s bet that it's going to happen sooner?
Back in March, I said not before September and you said way before Sept. what changed your mind?
This was provided on another board. I wonder if it can be applied to the upcoming Rett trial?
http://www.jdsupra.com/legalnews/what-the-21st-century-cures-act-did-for-58494/
I'm also leaning towards good news. If they waited until end of day Monday, it might be impossible to hold back the enthusiasm from years of hard work. On the other hand, why torture yourself for a whole day waiting to deliver bad news.
More than $10 would be nice. Maybe with a buyout if results are strong enough.
Good luck to all!!
Actual we will have one both days!
I thought the volume was awfully suspicious today (4-5x normal). Some nice block trades, either short covering not wanting to gamble over the weekend or longs knowing the outcome or was the news earlier today, to take advantage of the pop on Monday or was the secondary taken advantage of today with the added help / "slip" of AH PR? Somebody knew something.
In any event I hope it is great news and we pop to 20. Is 20 realistic with great results?
10% of the daily volume on the last trade of day. 28,327 shares
The top ten trades today were between 3,400 and 5,000 shares. Anemic or pathetic or both?
LOL...one day will we grow legs and jump from Lily pad to Lily
Tom,
You said: "do you want positive bullish hopes or the truth"
I'm thinking the truth is we have bottomed at the 5.60 - 5.65 range and the positive bullish hopes begin as soon as we get news. In the meantime, it's just ho-hum, nobody selling and nobody buying. It's just the computers playing with themselves.
In any event, news is around the corner so I don't expect any major moves until then.
Sure seems like there will be news AH today or Monday pre market. Monday is May so we should be hearing hearing something soon.
And it took only 15k shares to drop it back down 0.15. It looks like someone is working real hard to drive price down in order to accumulate.
It sure seems everyone is just waiting for news. Okay I just pulled up my seat. The next couple of weeks should be of great anticipation.
I wonder if Missling was waiting for new FDA chief to get appointed to work the 21st Century Cure act. Give it two weeks. Maybe by Tuesday the 16th we hear something.
IIR still hasn't replied to my email regarding Rhett timelines. I have a feeling they are not because my question will be answered shortly with PR.
Drum roll please!
I would rather see Rhett trial started and resolution of patent before partnership. Let's get share price to double digits (like 25) before partner.
If I knew when news would be released, I would be selling my shares and buying near term options. I am hopeful we will hear something on the Rhett trial by mid May. I say mid May since it is the half way point of Q2. Remember though, my hit rate is 0.0001%, so it is very likely I would be wrong.
That should be insider information and if he and his clan traded on it, then...
I don't think AF can move share price like he use to. I believe there are many believers and available float shrinks each day. As far as news, I'm thinking the next big news will be the launch of the Rhett trial. Long and patient, although I want to hear the start now. :)
FBG, the only 15 we should be discussing is how long will you badger me if I was 15 minutes late to your house for dinner?
Can we give it a break? Let's accept the fact he is the CEO and wait until we mature enough to see the real value of all of our investments.
Hi Tom, I believe your downward bias is correct without any news. Volume has been low and minutes go by without s trade. The trades that do occur are small. Many are less than 100 shares. Without news, there isn't much incentive to drive stock up. The way I see it, whoever believes we have the goods are long and waiting for the catalyst news (Rhett's trial, partnership, patent approval) to hit and then we will see a nice pop. Until then, those that are not strong believers may have already started to lighten up and may continue to do so. The trading patterns for the last week or so seem to be traders. Buy in the morning and sell in the afternoon. To me it may make more sense to buy a few minutes before the close and sell the next morning after a brief run. Since I am a believer, I'm just going to hold and wait it out. If it drops a buck, then some lucky souls will be able to get in cheaper than today. If it goes up from here, I'll be happy I didn't lose out on any profits by timing the moves. With all that said, I can't believe we will go much longer without any news. I believe we will hear something big within 3 weeks, let's say by Tuesday, May 16th end of day. Time will tell.
No, just a 16k share trade at 8.63. I was expecting larger.
50k+ shares MOC today? Trading looks like that may be the case.
Thank you Bio and thank your friend for all of us too!
Nice posts Bio! Their comment "just getting started" plays into AVXL. I concur Biogen's MO is to test everything (even combos) with the hopes one or more or a combo will succeed.
I'm sensing if we break through the 8.60's soon we will end the day at 8.90.
Reyeton
You stated"The next phase of the trial could then narrow down the participants in the upcoming trial, to individuals with a similar profile to the 6 super responders."
If that is the case, then would you think A2-73 would be tweaked to benefit other profiles or is that where A3-71 comes into the picture? If so, then that might explain the elevated prominence of A3-71 at the last conference.
In any event things are looking up.
Missling is fighting very hard for the patent. Perhaps poison pill is in the event we fail on obtaining patent.
I wonder if any potential suitor is feeding patent office with rebuttals?
The patent issue may explain why we have settled in the 5.70 area.
My guess is we are between item 3 and 4!
Send a note to IR. I did last night. Will inform board once I receive reply.
Tx - I believe earlier because we will submit application sooner than most expect and if EMA takes its normal time we would still receive the nod early because we submitted early.
Thanks stockdoggy. Not as high as previous coverage/price target but nice just the same.
I couldn't find any news that would explain today's AH volume and price movement.
I think it's (EMA approval) going to happen a lot sooner then most expect.
Someone posted an article a week or so ago which said an European BP may make a preemptive strike on U.S. Bio companies before they can be out bided by the trillions repatriated.
Since we are discussing predictions, I predict we hit 6.02 tomorrow. I'm right about .0001 of the times and tomorrow may be one of them. I'm just hoping my long term picks are better than my short price movements.
Better to be a passenger on the train then a bum lying on the tracks.
I believe it was mentioned that the Rhett org has already identified a pool of potential patients so one would like to believe they know who they will be and as soon as we get the green light it should be a very short time to start.
Wouldn't it be nice that upon the PR on the start of the trial it is also announced that the full enrollment is also completed and there only only days between the first and last treatment! That's what I hope is happening. It should be there goal. They've had enough time to anticipate everything.
Nice block trade of 98k shares right at the close
Right on Bourbon. If we get the Rhett trial started AND if Biogen's testing was positive, then Biogen (and perhaps others) will be under the gun to make a move knowing the lid can be blown off in 12 weeks or so.
Surely, Missling had contingency plans in the event the preferred shares and or poison pill didn't pass so let's see what progress had been made on all of our fronts. It's time to show visible progress as in a PR of trial starting.
I say until we hear news we are range bound with slight bias to downside.
When Biogen finishes testing and IF the results are positive enough for Biogen to make a bid for us, I would think several other BP's are lurking and will most likely compete with Biogen for a piece of us (if not all).
Rhett trial commencing or Biogen's retesting results, which will come first?
Agreed. So the company shouldn't keep mentioning the importance of the data if not for public disclosure. Coke doesn't always talk about its secret formula.
What we need is the announcement of the Rhett trial starting. It has Orphan status, 21st Century Cures Act, a willing partner who is financing it, a pool of participants and the fact it's suppose to start in first half of 2017. Let's not wait until June 30th to announce. Let's hear about it starting now. Let's start something early. This should be priority one! Forget the conferences, round tables, etc., they are a waste of time especially when the time will be better spent getting a trial started ahead of promise. Time for the rubber to meet the road.
As far as the PK/PD data being available, my thought is as long as they are adding data it will "never" be done. Share what it has today. If it gets better with time then provide an update.
I'm hoping for something profound within the next 30 days. Let's hope!
Early submission (and thus an earlier approval) is happening. DOC did state that obtaining EMA approval on the manufacturing plant was the last major hurdle, so I bet the approval application was 90% completed and was just waiting on the manufacturing go-ahead to complete the application. If it's not completed yet, it will be very soon.
Great things are about to happen.