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Source: LinkedIn
The official ingredients - with their functions:
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- nucleoside-modified messenger RNA (modRNA) encoding the viral spike glycoprotein (S) of SARS-CoV-2
RNA is a template to produce a specific protein.
In the vaccine, this message tells our cells to produce the viral protein that will trigger the immune response to the virus.
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- (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis (ALC-3015)
- (2- hexyldecanoate),2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide (ALC-0159)
- 1,2-distearoyl-snglycero-3-phosphocholine (DPSC)
- Cholesterol
These are fancy words for 4 different fatty molecules. These assemble into capsules that contain the RNA. These fats aid in delivery and protection of the RNA.
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- potassium chloride
- monobasic potassium phosphate
- sodium chloride
- basic sodium phosphate dihydrate
Again, fancy words for 4 salts. This formula is actually phosphate-buffered saline (PBS), a common buffer. This normalizes the pH of the vaccine.
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- sucrose
Just sugar! It is a cryoprotectant to ensure the lipids don't get too sticky in ultra-cold storage.
Thank you! Perhaps hiring a sales force for their new FDA approved drug?
EOLS ITC decision scheduled for tomorrow. Should be interesting!!
Thank you sir!!
Just an incredible story!!! Congratulations sir. It’s had a little pull back from almost clipping $21. Presently would you care to comment if it’s still a decent buy today? I see they increased dosing and are awaiting results. Thanks jbog.
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“Also, might be the FDA members' husbands/wives need DAXI - yesterday!”
And all of us utilizing Zoom, Skype and Teams! I looked like hell today. Sign me up for a round of Daxi!!
Not very impressed with the website. I am impressed with the company so let’s see how this all plays out. 6 month delay on FDA inspection & approval?
Great watching your lottery ticket run sir! Didn’t have the ability to jump in myself albeit don’t mind....it’s a story I’ve never witnessed myself and appreciate the excitement for you!! Cheers and best. Rich
Added to my position today. It’s unfathomable this continues to be so undervalued. GLTA
Based on this, I foresee the same announcement apropos RVNC and the application of DaxibotulinumtoxinA.
I shutter to think, as that was a disappointing situation for all concerned.
Being vertically integrated should help de-risk the RVNC business opportunity.
Fascinating sir. I don’t have a clue myself as to the “reset” theory. Hopefully both the wrist and the chest discomfort will abate soon. Take care.
Excellent point and thank you. Should be interesting how this all plays out over the next 12 months.
I have to admit, I’m surprised with the lack of guidance from the FDA apropos the delay in auditing the manufacturing site. Are we looking at 3 months, 6 months or 12 months delay? Strikes me odd that there was “supposedly” no communication from the FDA on guidance for this required action item.
Appreciate your response and thoughts on this very much. I’ll keep researching this company. Take care
Hi, curious if you believe this has an opportunity to flourish into a serious investment opportunity? TIA for any guidance
Thank you sir. Certainly will be interesting to see how this all pans out!!
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“Just about every twitter post is asking the same question. I'm guessing there were a few traders in it for the PDUFA pop but when it didn't materialize pre-market decided to bail and the shorts pounced. Approval was pretty much expected.”
In this unstable market, I am wondering if we will see the same with RVNC come November 25th. Thoughts? TIA
Excellent point. Thank you for sharing.
Perhaps I am too optimistic! I viewed the results as positive and like the lower dosage. Clearly the market disagrees with my assessment.
“I figured it was because no additional benefit was found with the higher dosing.”
My perspective FWIW, I like the efficacy of the lower dosage as compared to the higher dosage. Sometimes less is more and less of an over all risk of adverse events. :)
Bought more today...65 days until we formally hear from the FDA. Cheers...
Thank you kindly sir! I’m looking forward to these investment ideas. Great story and a very sincere congratulations!!
Jbog,
Thank you kindly for sharing your story and the rational behind your investment in your “lottery ticket”. Incredibly impressive gains and certainly will look again at this company.
One easy question for you, what intrigued you about this company enough to invest the $15 K originally?
Thanks again sir for your story and contribution to IHub!! Regards, Rich
A sincere congratulations sir!! It’s been fun to watch.
LMAO!!!! Now that was uber funny jbog.
Thank you for addressing this Dew. In your opinion, are the outcomes in line with your expectations for both studies? TIA
Thank you for sharing. Do you foresee RVNC needing to raise any more funds going forward? TIA
Thank you for sharing sir. I for one appreciate your updates. Respectfully....
Market cap - $3.7 billion
Good morning all. I have to admit I’m astonished how well this PPS has held up with an astonishing market cap. I may be wrong but aren’t we many, many years away from this company selling one of their new candidates.? TIA
Disclosure – I haven’t owned this company for approximately two years.
Thank you jbog, appreciate the link very much.
Separately, if I recall correctly, you have/had a career at OFD. I’m seeing a huge uptick in demand for bionutrients for probiotics. The perception is some strains of probiotics “may” help strengthen the immune system. Are you seeing this increase on your side if I may inquire? TIA
Thanks sir. In your opinion, does this also apply to RVNC’s application?
I don’t have a Twitter account, any chance you can share the results here? I saw the poll after you posted it though. Thanks sir.
Thank you for sharing this news. Positive news for RVNC from my perspective.
Picked up some shares this afternoon in late trading. May do the same tomorrow as traders looking to reduce their risk and may bail before the weekend. Cheers to all.
Thanks sir for this summary.
Thank you kindly for sharing with us. While I am not a huge fan of this complex financing exercise, I am relieved to hear that long term institutions represent a good portion of the investors. From my perspective, this suggest that RVNC is investing in their future and pushing forward as though they are going alone. To my way of thinking, they are less inclined now in looking for a complete buyout. Just my 2 cents FWIW.
Selfishly speaking, selling out a market cap a touch more than $2 Billion in my way of thinking is too little. I rather they obtain a partnership and drive this forward 2 years and sell for more ($3-4 B) after they demonstrate superiority in many more indications. Just sayin. Am I being foolish here?
Congratulations jbog on TRIL. Admittedly sir I’m envious. :)
OMG HILARIOUS!! Haven’t laughed this hard in months!! Thanks gents and a blessed Happy Thanksgiving to all.