Know what…. This 5 million loan with convertible shares at 30 cents deal could be a teaser of a bigger plan for big financing going forward.
Could be revealed in the future that the same financier takes a position at 4 bucks and help gets us on the nasdaq
You see low share prices can work in favor of the company if the company has control of who they will sell shares too.

Hey you think Roswell Park might be one of the cancer centers that starts trials in DC Direct?
Roswell park prides itself on having the newest and best treatments available.
Maybe that was a bargaining chip in that amazing deal
And I am betting that the trial wont have a control arm where patients dont receive dc direct
Study will compare dcdirect with 2 adjuvant and or 4 promising approved treatments to weigh efficacy
And for ignorant people that would insist on a placebo controlled randomized study..
Those controls are only needed when the drug your trying to approve has only marginal benefits above and beyond the poisonous chemotherapy that’s standard of care.
Since there’s been no new cancer treatments in last 30 years we know how long a lung bladder breast prostate cancer patient will survive according to the stage.
So obviously we wont need a control arm because we expect results to blow past the .05 statistical threshold to show efficacy.
Just so you know most big pharmas run drug trials with thousands of patients to prove a little benefit of there drug.
Some Cell therapy companies have proven efficacy with 30 to 100 patients because the treatment is so obvious.
Looking forward to Roswell Park announcing the start of Dcdirect trials without any placebo control

Something that brings peace to me as I endure my legacy investment….
I have 99.9 percent faith in management that they wont sell me out cheap to whoever.
I trust and believe in there honor and commitment to doing good .

Us long term investors (or legacy investors as some would call us) are in a unique situation. We identified a treatment that met and surpassed its endpoints. We have seen milestone after milestone reached. Yet the stock price keeps going down.
Us seasoned biotech investors have never witnessed this before…
At the stage were at now in development nwbo would be taking off.
Just 10 years ago it was guaranteed a successful phase 3 trial lit the fuse for forward valuations.
Anyway much like the Canadian mining stock market the manipulation of retail biotech investors has lead to them taking their losses and leaving the market.
So we have a huge gap in the market where institutional investors cant and won’t invest in otc penny stocks regardless of market cap
So dont question your due diligence…
Most people are pussies and won’t invest in a declining stock. That’s why it works for our enemies to drop the price daily

Tell me how could the new ownership of 3 new phase 2 trials in dendritic cells from Roswell that are completely paid for in grants and run by independent investigators have a negative impact on market cap….
These trials could result in approvals if we get amazing results without side effects.Just a confirmation phase 4 trial

So BB I think what your saying is some smart researchers are already coming out with ways to improve DCVax... Knowing that they will be paying a licensing fee to NWBO for the initial work done for creating and validating the platform. It is promising that people are front running approval.
Like DDStock said there is currently 500 trials going on with Dendretic Cells. I bet 2 years ago it was less than 100 trials
Linda Liu said she's open to any potential combinations that can improve efficacy. She mimics what Linda P believes.

I can foresee after some big money deals for certain indications and making everyone whole, that Linda P will open up the technology to the world and allow free access to all our technology. Maybe in about 2 years or however long it takes for the world to recognize the value of this new treatment

Heres my always optimistic prediction of what could happen.
Based on the fact that dept of defense is paying for the latest clinical trial using dcvax for gbm in adolecents to 5 year old and the NIH has paid for trials and research for DC Vax.... And the fact that NIH has financially backed Linda Liu for many years.
I can see these facts used as backup for the announcement from Biden that he has been working on cancer moonshoot the last 8 years and he finally made some big advances.
At the same time he will announce approval of the first allogenic cell therapy in USA and the promise of what that will mean for many devastating conditions...
That was his ace in the hole to get reelected but now he can use it in his legacy speech and let the democratic party take some credit for it also.
So DCVax FDA approval before Nov is my prediction. But it will be announced by its USA partner... Merck
And Merck will be using the new manufacturing facility that DDStock talked about.
NWBO will operate Sawston to keep everyone honest.
I am confident that this board would know if there was a more promising cancer treatment on the horizon... and would discuss it...
Good luck visionaries.

what I am saying is this stock story has the most potential of any story in the history of good stock stories. And the amazing part is we know it's real.
Honestly there's a real lack of billion dollar companies listed that are changing the world.
So don't be so nieve and negative believing that well have a hard time raising money. Don't let them shake you out.
IF I had a billion and was looking to polish up my image... And be first in line if someone in my family got cancer... Yes I would be investing in NWBO...

Continued.
So what I am saying is this stock story has the most potential of any story in the history of good stock stories. And the amazing part is we know it's real.
Honestly there's a real lack of billion dollar companies listed that are changing the world.
So don't be so nieve and negative believing that well have a hard time raising money. Don't let them shake you out.
IF I had a billion and was looking to polish up my image... And be first in line if someone in my family got cancer... Yes I would be investing in NWBO

Here is the start of a story that might not be make believe.
As a precursor I grew up in a family that came close to proving out a billion dollar mining operation ..one hole away. We had family breakfasts of what we would do with 100 mill
The reason I bring that up is because in the 80s and 90s investors could believe in getting rich in a mining stock and later tech stocks internet stocks in 2000...
Anyway the game wasn't rigged until around 2006 or therabouts where they allowed blatant shorting and allowing traders not to have to cover short positions it is a company goes bankrupt.
Any I digress with my history lesson.
The huge point I want to get across is there's not a story stock around that anyone gives a shit about or is interesting.
TSLA kind of kool Nvida woowee but their success is also woorisome the other leaders just make money but are boring.
Biggest gold ever mine discovered... takes advantage of the indigenous population
Now introduce our story stock complete with a history of David versus Goliath.

Its interesting that Hiltonol/polyicl was not mentioned at the agm. And if you Google the query Hiltonol is it FDA approved it states
The supplied Hiltonol for use in commercial production and sale of any combination production will be completed grade and meet US FDA requirements for commercial product use. BOOM!

There hasnt been a deal because big pharma offers crapolla... They are not negotiating in good faith.
A big investor will step up with few hundred million at 3 bucks and get us fully listed and go into the records as first one to take a chance.

Hi Viking, Iam suprised you put so much confidence in the posted short numbers. If we surmise that half this board are paid bashers then we have to believe there here because of a huge naked short position yet to be covered.
The short intrest reported in a maipulated stock is just another tool used to control direction setiment.

Lindas confidence was definitley there.And I would say she was holding back her exuberance.
Lets revisit all the due dilligence that amazing ddstock has given us. I am also a believer in announcement of cancer moonshoot program.
Nih funded for years thus allowing credit to be taken from Biden, gliobastoma trial which is specific to Joe Bidens son cancer,
Backed up by 2 journals,
cancer moonshoot talked up for years then silence for last year.
Makes sense to announce this in late September October to get maximum effect.
Nobody on this knowegable board can point out a better cancer treatment thats close to approvoal or with substantial efficacy.
Cancer moonshoot would be his hugest accomplishment. Something to be very proud about.
I can see him getting some credit for his efforts.
With the wording something like this.
Merck is pleased to announce that together with the

So from my recolition of the previous 9 agms that I have been here for this is the first time Linda P did not put the kibosh on expectations.
In the last 3 or 4 years Linda P would come in and tell it like it is and say were not there yet. And before that from 2015 to 2020 she would talk like were very close and get investors to hang on. I always believed she believed the company had a great chance of succeeding so she said what she had to to keep retail invested.
Anyway the sincerity in her words and the confidence in her tone is so very reassuring.
If you can read into her presentation you might see like I do someone very confident of success.
One of the greatest rewards of achieving success in something you have put 20 years into is the joy you see in the people that backed you all those years. Making dreams come true for average people invested forever is a great joy for Linda and Les.
And thats why she went on and on about the vote of confidence for the share true up. It made her feel wonderful that her investors trusted her.
I feel were very close to a change in setiment

Blah blah blah Kabushni, Youve been spouting negative sentiment continiously for days now. Elaborate explenations of every concievable negative scenario...
Are you another poster here to help us tamper down our expectations?

I disagree that nwbo cant apply for approval using current manufacturing methods. Current cell therapies approved are very expensive… not to mention side effects

Charles River Laboratories to Acquire Cognate BioServices to Create a Premier Scientific Partner for Cell and Gene Therapy Development
Download PDF
– Significantly Expands Charles River’s Scientific Capabilities in the High-Growth Cell and Gene Therapy

Cognate plant was gpm approved then bought out by Charles river Lab for 875 mil.
Manufacturing is in place for USA. The quite says its so.

Why is yahoo volume 631,000 and Ihub volume 1,445,000
Yahoo volume was lower than Ihub last week also

Very promising thanks Follower.

If you believe GS, JPM, some Canadian banks,Citadel and other market makers along with 7 to 10 big pharma are conspiring in keeping new biotechs down that dont conform partner and follow wall street rules then heres a scenario for you.
This approvoal is happening and big money was told 6 months ago to make a deal now. And still no deal.
Britian needs this win and they will be shipping treatments around the world at a profit.
Biden is saving this announcement till Sept or October to validate cancer moonshoot and he can state that NIH has been funding this 15 years and recently increased funding last 2 years.
The king just visited Kings College and designated some award.He said hes researched new treatments.The new biotech park at Sawston has been described as best in the world.Its actually a no brainer that anyone older with cancer would choose dcvax therapy over chemo
So like I said huge money negotiotions going on right now and the cost of keeping stock below 50 cents is negligible compared to whats at stake.
Scenario of big boys offer....We buy in 300 million shares at 10 bucks a share.We give the ok to media to cover the story and we give alcolades to nwbo management and Linda Liu and ucla. Lawsuit is settled for 500 million with no discovery. No movie done with nwbo ok
Full backing to bring Dcvax and direct to market quickly.
If they dont accept some kind of deal along these lines they are told they can expect the same pushback they experienced last 15 years.
thats my thinking tonight. Best to all the believers
We all know there is no competion close to us in cancer treatments.

Hi Dstock and thanks for what you do. Regarding Hiltonol the original patent recently expired and if you google polyicl the drug is available for sale through many compounding pharmacies. The company has applied for a patent for a more potent variation with manufacturing improvements.
I would bet the new version of hiltonol has been used in the specials program and also trials started in last few years.
A partnership between nwbo and hiltonol would pretty much put a nail in the coffin of the pharce that big pharma actually has cancer immunotherapy treatments that work for many and have low side effects.

So your sugestion is to use GS or JPM to do a secondary offering and your putting 10 bucks out there as the potential number. You do understand that those shares will go to cover the naked short position along with allowing others to go long the stock. And it would probably be tied to a settlement with the market makers admitting to spoofing but no discovery.
We have come a long way thats for certian. As the conversation has now changed from no chance of approvoal to approvoal wont move the stock price very much.
Huge negotiations going on right now I believe....

Les job is to confuse the enemy... big pharma. Not keep retail informed. Consensus is now that in 2015 nwbo management knew they were pushing out approvoal to 2021 to prove overall survival and more important create closed manufacturing to do away with expensive clean rooms.
They knew this yet held out the carrot of trial completion to retail for years to keep this company alive. And it worked!
So now some are complaining that Les dampened expectations with his words on big biz show. But the reality is he created false hopes and expectations since 2016 to keep retail invested,and keep this company alive. Now when his message is not to count on immenent approvoal some are taking that as gospel.
Think about it... we have been waiting since 2015 and the message was were on the cusp of breakthrough. Now the last year very little promotion and no cheap stock sold .

Thoughts tonight are that Britian has had a plan to capitilize finiancially on selling dcvax to paying customers around the world. Hence we had the approvoal of Advent to manufacture and ship anywhere. The model of paying customers has been fine tuned for last couple years...Probably 50 grand usd upfront which includes 2 shots the 25 gs a shot after that..and cost decreasing after 6 shots.
Compasionate use is currently approved for any indication so NWBO can collect data on all cancer indications while getting paid.
Obviously this scenario only works with approvoal of flashworks device which I believe will happen quicker than expected.
My reasoning for this scenario is never underestimate the British... who were the world leaders before second world war. They know how to make money and previous colonies still respect them and the rich in those colonies will gladly pay for a new cancer treatment without side effects.

My

I can buy hiltonol right now from a compounding pharmacy. Go online and check it out.
Once its approved those pharmacies wont be advertizing it anymore because they will be sued.
Iam hoping that specials program has been including polyicl (hiltonol) in its treatments since 2017... and the results of that real world data are going to be announced a week after the nature article.
Mhra approvoal, nature article about polyicl and dcvax 60% alive and then numbers alive from specials program treated at the optimal timing with and without chemo.
Seems to me like anyone accepted into the specials program has been sworn to secrecy as no one talks about it. I bet when they are allowed to speak they will be very vocal.
So the conversation wont be about comparing 5% survival to 13% survival...It will be about comparing 5% survival to 60% survival in the most lethal cancer.
Allow the big investor in first with a purchase of 100 million shares at 3.50 to set a base and get uplisted then let the news flow.

Who in there right mind would not want this treatment for their child? Personaly I would pay for dcvax treatment in england and I would buy polyicl from a compounding pharmacy...that would be if its not already being administered as a treatment which I bet it is. You know kind of like the trial how it let all patients receive dcvax if they progressed...Every patient now is advised to ask their doctor for polyicl.Which is available.
So all you relentless bashers of dcvax tell me what you would do if your daughter was diagnosed with glioblastoma...
How would you proceed.....please enlighten us

So India connection now… we know Britain and India are connected through history and commerce.
India was first to approve a dendritic cell therapy (obviously inferior to dcvax but nonetheless somewhat effective).
Some poster stated that lucephries collection was already occurring in certain areas.
So if they include India in submission with Canada and the others it would be a big boost.
Start with approval of importing the treatment with the plan to have manufacturing in India.
India has a huge drug manufacturing operation and they ship around the world so don’t underestimate them.

So a pragmatic guess as to when MHRA will approve would be early approvoal...anytime after march 22 meeting.
My thinking on this is that Britian is proud of this new advanced therapy. A part of the story that will be told for the next 20 years is how Britian expidited approvoal of dcvax and moved along approvoal for other indications also. You only get one chance to approve early...and because its been 3 months thats also enough time to properly review.
British know its going down in the history books as one of the greatest breakthrough in cancer treatments of modern times. British have liscened Advent for manufacturing and export of dcvax around the world for tumors....Not just gbm. Obviously there keeping track of efficacy in other cancers. It would be wonderful if Nwbo has been including polyicl in all treatments for the last year and a half.
I believe we do know that every patient that that is treated in the compasionate/specials is followed up and entered into a data base that is now finally accepted for evidence for regulatory approvoal.
Ohh I would love to see approvoal in Britian for GBM along with the announcement that anyone outside the country can pay 200 thousand pounds for treatment for any indication.
And to follow up in 2 months announce flaskworks approvoal and drop the price of treatment to 150 thou pounds.

If negotiations are stalledand they ask my advice I suggest its time for NWBO to announce a partnership deal with one of the 170 companies that have approved PD-1 treatments.
Choose a company that has shown improvements beyond the leading Pd1 (keytruda) add polyicl, get 10 or 20 million upfront with the deal backloaded. and do a deal for a smaller indication like pancreatic cancer.
This might be catalyst needed to move the negotiations along.
Or on the other hand the long awaited sweetheart deal is already negotiated.
Heres something to think about.
We have a huge binary event that can happen any time from now to May 30th. Thing is the board shorts make no big deal of this binary event. Previously over the last 20 years when I got ripped off by the cartel they would pump the stock up to high prices before decisions because they knew the fda outcome I lost a shitload of money and did allot of praying.
Anyway looks like the plan is to play down this approvoal. Shorts are setting expectations low anywhere between 1.50 and 3 bucks.
I think they are hoping cash starved long term shareholders sell 10 to 15% of holding down there in the volatility they create.
Good luck visionaries!

Oncivor article pre written so people can research Oncivor after partnership news realease and or nature article. Thanks for link norisk

Said a prayer for you Smokey, a cancer diagnosis for self or a loved one is what brought many investors here. Its sad that real immune therapy treatment is still not available.
On another note you dont post often but your sincerity has always shone through.
All the best on your journey.

Global CDMO Calalent was just purchased for a stagering 16.5 billion usd by Novo holdings (whoever they are)
Previous to this deal was fisher scscientific buying Brammer bio for 1.7 billion
Cdmo for cell and gene therapy production is on fire. As stated the goal is to cure current bottlenecks constraining production of cell therapies.

This is from Bioimformant, a cell therapy information portal. Look at the dollars being poured into this unexciting treatment.... Anyway on the other hand theres lots of potential partners coming up with better efficacy and less side effects that would love to partner with dcvax.

CAR-T funding isn't only gaining traction, it is surging. At first, the trend was subtle, but the tide has swelled as CAR-T therapies like Kymriah, Yescarta, Tecartus, Breyanzi, Abecma, and Carvykti have reached the marketplace and created a CAR-T funding wave.

In recent years, CAR-T start-ups have been richly funded by investors eager to get into this trending area of regenerative medicine.

Worldwide, more than 170 companies are engaged in developing CAR-T products and therapies. These CAR-T therapy companies have developed nearly 970 early and late-stage therapies. These companies have also signed an incredible 98 collaboration deals to progress the development of various CAR-T product candidates. Of these, 33 collaboration deals have disclosed their financial terms, accounting for a total of $21.7 billion in transactions. If an estimate is made for the collaboration deals that have not disclosed their values, the total value of these 98 collaboration deals would be in the range of an astonishing $63 billion.

Over the past decade, CAR-T companies have also attracted venture capital investments worth an incredible $6.7 billion, enabling these companies to invest heavily into their infrastructure and product pipelines.

During the same period, the CAR-T companies managed to raise an impressive $5.8 billion through IPO funding to further strengthen their technology platforms, clinical trial programs, and corporate efforts.

Within this nascent industry, with over 417,801 patent records and 4,024 granted patents, large pharma has increasingly been seeking to enter the CAR-T field by licensing rights from existing patent owners.

Among the financing types analyzed in this report—which include CAR-T industry IPOs, licensing deals, collaborations, strategic partnerships, and M&A deals—M&A deals constitute the largest financial percentage, accounting for an astounding $95.9 billion over the past decade.

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Heres my prediction of what can happen any day now. Based on the common assumption that some hundreds of millions of shares need to be purchased. Our enemies like to front run news so they can operate in a vacuum. This gives them more control of the narrative.
I predict there will be big run up before news. The goal is to accumulate as many shares as they can from 1 to 5 bucks. People have asked why shorts are not covering at these current prices and the answer is simple. Obviously there's no shares available around this price. They need 100s of millions of shares and they will run the stock price up and accumulate then run it really high for a couple of minutes selling to each other painting the tape and then drop back... So next time it hits that price your selling.

The strategy is to operate from a manipulated low share price and then claim that your greedy by not taking a 5 or 10 banger... and all while the price of the stock keeps dropping from this manipulated high stock price. Stock waterboarding... up fast down slow...
And this happens again and again at a higher price while accumulation continues.
This prediction only concerns the shorts covering . If an investor that was trying to negotiate a buy in with nwbo and could not reach agreement and decided to buy on open market that could create competition for shares.
So I am predicting a bull raid out of nowhere to happen anytime before March 07.... because at some point some rich dudes are going to see what we saw 5 years ago. And jump on that pr bandwagon.

Thanks beachhyena, so the kings being treated in Britian by a new progessive therapy.
Fact is DCVax is approved for use by payment for all solid tumors not just gbm.
Fact 2 is it was stated that advent is the most advanced cell manufacturing plant in Britian. So it would make sense that this is where his treatment comes from.
Fact 3 is if there was a competing new therapy, or drug even close to dcvax the miscreants on this board would have been raving about this new drug and we would be aware of it...
So my thoughts are 90% chance King is using dcvax.
Probably not ready to announce that right now as this was a new development that wasnt in the timeline.
But perhaps in 6 months and after dcvax has been approved for gbm the king will say he feels the new treatment is working. And for the cost of 250 grand people all over the world can pay for a new cancer treatment that actually cures without side effects

Flipper along those lines of wondering about how Britian would benefit by being known as the quickest yet thourogh regulatory bodies now approving new therapies...
I am hoping that they offer full price medical treatment to any country they have relations with around the world. Britian is still hugely respected.
Anyway it would be so amazing for a political party to announce that we can afford to offer this new treatment to our British citizens and its being subsidized because the British govt is making money selling it full price to paying foriegners.
I know Advent now draws proccesses and stores your adipose stem cells for 20 grand.

Here is what will happen regarding off label use of dcvax. As soon as its approved for gbm it will be requested by patients for all types of cancers immediatley. The treatment will be an immediate success only limited by manufacturing capacity.
Smitty saying doctors will be hesitant to prescibe over threat of legalities is laughable.
You know why some doctors get sued for prescibing off label? Its because they prescribe additional expensive chemo posions on top of the chemo they are already taking.
Has anyone else ever seen people on 10 drugs or more.
So if a patient asks for a new treatment thats totally different than a doctor suggesting that a patient may benefit from an addition of another drug with additional side effects.

Excellent post Biosect regarding a realistic market cap going forward. Love the added colour!