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I don't believe you're right, but much will depend on how the release is done, and how it is received. Does the release suggest how unique the vaccine is, how it should be considered a new paradigm in the treatment of cancer.
Of course I'm not speaking of the words in the company PR, they would be considered hyping the vaccine if they said it, but it's how the media reports on what the vaccine represents.
If the media totally fails to pick up the news on the UK approval, the reaction to it may not be that great at first, but it will build over time. On the other hand if we get a great deal of media attention, no telling how high we may go.
Gary
OMG another good omen?
The ihub add at the bottom of my post is the Rich Guy piece of the Monopoly game!
I’d go outside and see if I get crapped on by a bird for further luck, but it’s already dark and only bats are flying. I don’t think guano is lucky except for plants and bugs
Hi Folks,
I opened a single fortune cookie tonight and it read:
You will receive important news Thursday!!!
Today is Wednesday so I won’t have long to wait!
Koinkidink? Approval news?
And what about Naomi? (Real old reference that boomers might remember)
You're right, in the past year we've really not had great news, even once. The good news has been few, and far between. That's in the past year.
I believe the chances of great news in the next year are great. I suspect that we'll get UK approval, EDEN approval, and at least submissions to the FDA and others. I think most here would agree that if these things occur it should be a really great year.
Gary
I hope approval PR out when NWBO trades at 80-90 cents. Approval would send it to $2s over night. If approval news come at 33 cents, I am not sure what price NWBO will be traded afterward.
A pr, from nwbo? HAHAHA, I guess it will be delivered by a flying pig fro a froze over Hell.
I remember that there were two levels to this. I think, years ago, some thugs from Hungary or Ukraine were hacking PRs to news agencies. Clearly illegal.
I also think some people get pinged (from whom I don’t know) a PR was sent for release after some company sends it to news agencies for next morning release (after the bell), but no idea if this is true or if it’s legal.
Anyway, on stuff like this, I just don’t know at all.
PS: attilathehunt, I didn't mean to put down your idea about a pending PR. Thanks for the suggestion and I love it! Maybe you're right, because I don't know how these thing are done with PRs. Sharing ideas helps us all get to the bottom of these issues.
OK, attilathehunt, I'll be sitting here with my computer waiting to see that amazing PR at 9:31 a.m.
But seriously, do you think our management is going to send the powers to be a PR the day before they want it to be released? It would be easier for me to believe in a leak, even though management has done a good job keeping secret their business dealings. It's also easieer for me to believe Flipper's suggestion that MMs are basically creating fake buys and sells, just I can't see why.
Usually trades like that (up or down) may signal a PR was sent to the service that releases them...
Would not be surprised to see a PR at 9:31 tomorrow.
Yes, I've waited hour to buy a 1,000 shares at ask ora smidge over ask. Makes you wonder.
“Idk” “just a guess” 😶 Seriously, LC??
Your posts are baseless defamatory rumors.
So, now you want us to believe that they like to screw their relatives with worthless gifts?? Or did you mean that they’re involved in some kind of securities fraud conspiracy? 🙄
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=175134306
I beg to differ
Once you have a crossover you de facto are treating rGBM because of the progression being new growth of tumor imo.
The mods would have you all believe that this DC (Washington) crew have no government contacts.
I don’t know, I just wonder how someone got the market makers to respond so quickly to them. That’s what really caught my eye. When I buy, it’s like molasses. Today was like molasses, then boom, on seemingly no news, boom, the market maker moves like ⚡️.
You're right, Flipper. All executed in the same second. 15:49:34. With NWBO, sometimes it takes many seconds or minutes between trades, so those 5 trades of 75,000 shares each (375,000 total) in a second are quite unusual. Maybe you're right that someone's bouncing trades back and forth. But then, what's the point? Why bump up the number of trades made in a day?
Trades today in NWBO:
15:49:34 0.335 75,000 Sell 0.335 0.3378 2,158,482 309 nasd
15:49:34 0.335 75,000 Sell 0.335 0.3378 2,083,482 308 nasd
15:49:34 0.335 75,000 Sell 0.335 0.3378 2,008,482 307 nasd
15:49:34 0.335 75,000 Sell 0.335 0.3378 1,933,482 306 nasd
15:49:34 0.335 75,000 Sell 0.335 0.3378 1,858,482 305 nasd
Idk, maybe on top of all those millions they gift relatives for a few hundred thousand while maintaining control?? Just a guess.
You do try awfully hard… :( Difficult for you to accept that the company is moving forward in the UK, and you’ve never claimed knowledge of the FDA too… but here you are, pretending to know things you do not actually know…
The FDA acknowledged in their article about using external control arms that for cancers such as this, for ethical reasons, a control arm in the trial may not be practical…
But yeah, for you, that’s nonsense. Makes sense that YOU would say that given your nonstop need to plead this bizarre case of yours. Let the regulator work it out. You claim to know they will fail it and not to own the stock… so let the regulators deal… or are you only interested in the stock price, and sabotage? Seems the latter…
LC,
I doubt that much of your statement is close to accurate, but even if I believed every word that you said, your implication is still illogical…
Why would somebody holding 130 million shares not be acting in their own best interest to maximize the value potential of those shares? I would.
You expect us to believe that the Harvard lawyer doesn’t know where her greatest wealth opportunity can be found? She is wealthy already, but she is not stupid. Do the math, sir 😶
“Published statements and other publicly available documents affirm that Northwest Biotherapeutics is strongly committed to transparency, regulatory compliance, and the achievement of its long-term business objectives, as evidenced by its ongoing progress with regulatory authorities in both commercial approval and manufacturing. Moreover, it is important to recognize that the leadership of Northwest Biotherapeutics, including senior management, are significant shareholders in the company. As such, they have a direct, vested interest in building assets of real value that will propel the share price upward. It is illogical to suggest that the leadership would act in anything other than good faith, as their personal financial interests are inherently aligned with the success of the company and the realization of an exceptionally high share price. This alignment further reinforces the leadership's commitment to the company's sustained growth and value creation for all shareholders.”
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=175094676
Be well GGB!
Thanks LTR. Yeah, I think the fact that these people feel the need to constantly comment and are either shorts or being paid by someone, suggests that some interest thinks that if they do not constantly invest an immense amount of effort and time, the company and stock will do way better and that will harm their interests. I don’t think there is any other reasonable explanation for their immense, intense, nonstop efforts. It’s their tell.
She paid zero for those shares while receiving $500k to $1M in salary and also receiving likely tens of millions for Cognate deal while having another $100M UK pure play in the works.
Investor082,
LP is a shareholder.
You’re spreading baseless rumors. LP is holding about 130 million shares, so who is she going to “sell short” exactly? Herself??
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=175094676
Agreed.
However, you fail to recognize that no institutional investors will back this management and purchase decent quantity of NWBO shares even after UK approval.
LP will sell shareholders short once again and nothing will change much. Just wait and watch!
And if that was, and lets pretend it was hacked and read, we still would not know if the purpose of the trade was to cover, short or what?
It means I grow weary of your artificial BS.
Usually trades like that (up or down) may signal a PR was sent to the service that releases them...
Would not be surprised to see a PR at 9:31 tomorrow.
LC,
I’m not exactly sure what that means but I will choose to assume positive intent and accept it as a compliment. 😉
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=175139922
lol IC then u are a true loser ..
U have been here since 4/20/2010
So more than 14 years and 6000 posts are for your amusement …
I beg to differ … u have some financial incentive to waste your time on a penny stock board ..
Whatever it is, I hope u end up in jail for
It
LC,
I agree. Capturing the rGBM efficacy data was CORRECT. The P3 demonstrated exemplary execution of the science method performed in service of patients and to advance the field of medicine. It was brilliant!
The medical community must have learned a lot from those astonishing rGBM data, and they will continue to learn. Today, the ongoing UCLA combo study for rGBM has been very enlightening as its interim data emerge, and 100% of the trial participants in the randomized controlled study have the benefit of DCVax-L because its efficacy was discovered over the course of an earlier clinical study.
The whole point of medical research is to ease the suffering of the sick and benefit humanity—that’s why Dr. Liau is a genius and deserves the Nobel Prize for her groundbreaking, ethical, and compassionate trial that led to great discovery.
The World Medical Association Declaration of Geneva included these simple words in their Physician’s Pledge exactly 76 years ago in September, and they were again adopted by the WMA General Assembly in Chicago in 2017:
“I WILL PRACTICE my profession with conscience and dignity and in accordance with good medical practice;
I WILL SHARE my medical knowledge for the benefit of the patient and the advancement of healthcare.”
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=175135718
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=175135190
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=175123171
Actually, your spin is too dark. If it was something to do with a financing, NWBO might not know the very next day or whatever, let’s say, they would get a decision. If so, they have to keep the lights on, so another financing would not necessarily signal some longer wait, it just means the bills are due?
I don’t know if anything was awry, but it seemed odd.
Hopefully Posner's team is aware.
Go ahead and try to deflect/redirect
I understand this type of thinking, but not saying that it is the case.
It is. But most of you really deserve it.
FALSE, the original trial design was ONLY for naive GBM patients. The added treatment was a rescues treatment for those that failed on both DCVax-L and the comparator. NWBO added the R/R GBM arm in the last 2 weeks of the decades plus trial.
Even worse, the one guy who tried to stand up to it the disciples convinced poor green retail he was the enemy.
B.S. NWBO filed because they HAD to. They massively manipulated their P3 trial, totally redoing the protocol, endpoints and comparators two weeks before the end of the decades+ trial. They knew the trial failed using PFS primary endpoint so they totally redesigned it to give them a hope of success. Knew that the FDA wouldn't buy the B.S. as it violated multiple FDA Guidance guidelines so went to UK. Clearly UK isn't giving them favorable review process as that takes only 150 days and here they are just about a year and NOTHING.
10+ years of full time entertainment??? ABSOLUTELY nobody buys this.
Your concept of entertainment is.. disturbing
Do you think?? Long's by definition have been holding and clearly NWBO has been diluting every long's holdings to create the ~62% loss they've "enjoyed." Had new buyers been buying up shares this wouldn't have been happening. Instead dilute, dilute, dilute and loyal long's are losing value especially if they bought up the new shares. It's unfortunate that shareholders who have been losing steadily from this sinkhole.
If MHRA deemed this an important drug review, they would have done it in 150 days (5 months), instead, here you are almost a YEAR later with no response.
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Moderators flipper44 sentiment_stocks CaptainObvious Poor Man - Doc logic JerryCampbell |
“Now this is not the end. It is not even the beginning of the end. But it is, perhaps, the end of the beginning.”
~ Winston Churchill
Stylized Dendritic Cell featured on NWBO board since 2015
- Dr. Linda Liau, PhD, MBA, Professor and Chair, Department of Neurosurgery, David Geffen School of Medicine at UCLA
Clinical Trials
DCVax®-L to Treat Newly Diagnosed GBM Brain Cancer (NCT00045968) - Phase III (Double Blind)
UK (MHRA): DCVax-L to Treat Newly Diagnosed GBM Brain Cancer (EudraCT#) 2011-001977-13
DE (Germany - PEI): DCVax-L to Treat Newly Diagnosed GBM Brain Cancer (EudraCT#) 2011-001977-13
Expanded Access Protocol for GBM Patients with Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221 (NCT02146066) (Expanded Access)
Safety and Efficacy Study of DCVax-Direct in Solid Tumors (NCT01882946) - Phase I/Phase II (Open Label)
UK Clinical Trials - Study of a Drug (DCVax®-L) to Treat Newly Diagnosed GBM Brain Cancer
EU Clinical Trials for DCVax-L - Phase III
Dendritic Cell Vaccine for Patients with Brain Tumors (NCT01204684) - Phase II - at UCLA - Randomized (Open Label) testing DCVaccine with Resiquimod and DC Vaccination with Adjuvant polyICLC
Pembrolizumab and a Vaccine (ATL-DC) for the treatment of Surgically Accessible Recurrent Glioblastoma - Phase 1 (NCT04201873)
Dendritic Cell-Autologous Lung Tumor Vaccine (DCVax-L) and Nivolumab in Treating Patients with Recurrent Glioblastoma - Phase 2 (NCT03014804)
Dendritic Cell Therapy for Brain Metastases From Breast or Lung Cancer (NCT0368765) - Phase 1 - Collaborator: Mayo Clinic
Announcement of DCVax-L and Anti-PD-1 Monoclonal Antibody (Pembrolizumab) for Patients with Liver Metastases of Primary Colorectal Carcinoma Phase 2 Trial - November 17, 2016 - University Medical Center (UMC) of the Johannes Gutenberg University of Mainz
Cognate Bioservices - Owned by Charles River Labs
Website
Company Contact Info
Investor Relations:
Les Goldman (Company) (202) 841-7909 lgoldman@nwbio.com
Sign up for Northwest email list here (hit the subscribe to email list button in the lower right)
Company Headquarters
4800 Montgomery Lane, Suite 800, Bethesda, MD 20814 (240) 497-9024
NW Bio is developing cancer vaccines designed to treat a broad range of solid tumor cancers more effectively than current treatments, and without the side effects of chemotherapy drugs. NW Bio’s proprietary manufacturing technology enables them to produce its personalized vaccine in an efficient, cost-effective manner. NW Bio has a broad platform technology for DCVax dendritic cell-based vaccines.
Their lead product, DCVax-L, is currently in a 331-patient Phase III trial for patients with newly diagnosed Glioblastoma multiforme (GBM), the most aggressive and lethal brain cancer. This trial is currently underway at 69 locations thoughout the United States, Germany and the United Kingdom. NW Bio has also conducted a Phase I/II trial with DCVax-L for late stage ovarian cancer together with the University of Pennsylvania.
Their second product, DCVax-Direct, is currently in a 60-patient Phase I/II trial for direct injection into all types of inoperable solid tumor cancers, with trials currently being conducted at both MD Anderson Cancer Center in Texas, as well as Orlando Health in Florida.
They previously received clearance from the FDA for a 612-patient Phase III trial with its third product, DCVax-Prostate, for late stage prostate cancer.
DCVAX Survival Stories & Testimonials
Alice - Metastic Merkel Cell patient from Florida - ASCO 2018
Brad Silver - GBM patient from Huntington Beach, California - ASCO 2018
Sarah Rigby - GBM patient from Hong Kong - ASCO 2018
Kristyn Power - daughter of GBM patient from Canada - ASCO 2018
Kat Charles - GBM patients from UK - ASCO 2018 - as related by her husband Jason (Kat's Cure)
Prospective patients may contact NW Bio at patients@nwbio.com
UCLA Jamil Newirth DCVax-Patient Video - 2015
Allan Butler Video - National Geographic Vice President - DCVax-Direct patient from Phase 1 Trial with Pancreatic Cancer
NWBO - Patients Sunday Dennis and Jami Newirth - Enrolled at UCLA - Vimeo, Uploaded approx. May 2015
NWBO - Vaccine Helps Keep Brain Cancer Patient Alive (Jennifer Sugioka) - NBC Channel 4, Southern California, February 24, 2015
NWBO - National Geographic's Allan Butler Stage IV Pancreatic Patient using DCVax-Direct at MD Anderson
NWBO GBM Brain Cancer Survival Story of Mark Pace
Presentations
UCLA Agreements
Prostrate
DCVax-Phase II
DCVax-Booster
Upcoming Events
Videos
Linda M. Liau, MD, PhD, MBA - April 24, 2019 at University of Washington, Neurosciences Institute
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