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Science and truth makes people invest in NWBO. Ignorance leads to sellers, day traders and shorts .
I’m up 350% and refuse to sell until I hit 8000% , which could be any day.
Excellent. Sharing this.
I do not fault you for that.
The short narrative is wearing thin except for a very few. For me, time to look elsewhere. I sure haven’t bought into it for some time. Good luck converting people with the mantra.
stumble? bullshit. the 400+ failed trials stumbled. nwbo is on the verge of RA approvals. This is only a stumble for the short narrative.
I’d be happy with 10 bucks.
From my posts this morning you know I am not all sunshine and rainbows but I can easily come up with an over $100 per share price. As a platform for all cancer operable and inoperable you could get a million patients a year. You can do the math at $200K a pop.
But that dream keeps fading as I watch management stumble.
Aracaris limited is a whole owned subsidiary of NWBO. She might sign the papers but NWBO owns it along with the 13 acres in Sawston.
Losing money in stocks like NorthWest is not surprising
Yes, a federal court judge agrees with you. These bullshit negative narratives are only found online in fantasy land. Reality is a different story.
Have a great one HL.
Thanks Hspooner. I will take a look at your past posts for the companies working with Advent.
Photoshopping halos on to this management team does not make them Angels or Saints but they are lawyers which means that what they are doing is legal.
LP controls Aracaris limited, toucan, and Advent, who better to guide us through the maze.
https://www.dnb.com/business-directory/company-profiles.aracaris_limited.72a0e054c6154ef4449c5cdabe679c0a.html
https://opengovuk.com/company/08717711
LP is the managing partner of Toucan which owns Advent. LP is most likely one of many owners of Toucan. I think it is clear LP owns some percentage of Toucan but the exact ownership interests, no one knows. all imo
Linda powers owns advent, and established it as a UK company, I believe because the MHRA requires that a company be based in the UK for licensing purposes. I also believe the other companies they are contracting with are connect to LP, I posted the connections in the past if you want to dig through my old posts.
it takes 2 to tango. LP won't sell cheap. She also doesn't give up despite the years of false bullshit attacks and baseless lawsuits. LP and nwbo will have the last laugh.
I disagree with this false price ceiling. If I were short I'd be setting these sort of fake price ceilings.
SNO 2022 could be a bust for investors like NYAS and it will be if NWBO does not learn anything about effective public and investor communications and fixed lifelong bad habits in a handful of months is unlikely.
The last few months have proven to put charge in that spreading awareness among scientists has little impact for shareholders.
Furthermore SNO 2022 could well be another placeholder as we all learned the hard way back in 2020.
If something happens, great but slapping a bunch of logos up there does not counterbalance the historical cycle of hype and crushing disappointment here.
I'd agree with this nonsense narrative if I were a short. I'm long so I disagree.
have a great one HL!
Chris Brown and his hedge fund which is shorting nwbo would agree with this bullshit narrative!
LOL at this bullshit short narrative. I couldn't read past the first sentence.
have a good one Mav
complete nonsense. management needs funds to keep the lights on. they are using the minimum amount of c shares to do so.
Yeah I think the 70 per share comments are a pipe dream. We’re luck if we get to 2.00. Dilution is a bitch that bites you in the ass.
Now if you’re one the end of the dilution, like getting millions of shares, a buck increase isn’t bad.
we are in a quiet period. the pr push hasn't started.
Exactly, we’ve all seen this before and it involves months more of dragging out and another disappointment that many will not admit is even a disappointment.
Thanks TDD! A busy 2022 and more to come!
Thanks biosectinvestor. I have read through your response briefly and get the gist of what you are saying, but I need to read it a bit more for understanding and may have some follow-up questions for you.
The aspect of the company being shorted due to the terms of the contract reminds me of companies I've followed in the past that get themselves into convertible note financing with conversion prices determined by the average price "x" days from key dates defined in the note. The stock price mysteriously drops around these key dates and the stock gets diluted to the point of no return. Often these companies never do return. NWBO has been able to hang in there and it seems we may get to see them cross the finish line of regulatory approvals and ultimately becoming standard of care for GBM.
I agree with you. It’s done to benefit a narrow group of investors while poor retail gets sucked!
The PRs and statements at conferences in the last 10 odd years give us enough evidence that they have been BSing us, no?
From official statements in mid 2010s saying data lock coming soon to presentation by LP to scientific community in summer of 2020 at a virtual meeting that we will be unblinding in the coming weeks to LG’s appearance on big booze show in summer 2020 saying UK approval imminent….what additional proof do you need?
They have not been able to tackle the shorts for over 10 years now. They know what was coming and yet botched May 10. Given their repeated failures, no guarantee it won’t happen again. You could argue this is done to benefit a narrow set of investors to pump and dump, suck more retail.
Why are they hiding behind the quiet period for 2 years post data lock when they ought to be going out there convincing the street as to the real value of our platform, particularly with the stellar ph 3 data. Something smells fishy? Give me example of one successful biotech company that has taken this strategy? Importantly, why would you dilute the company at such low share price when you are in possession of such great data for months now and approvals that are imminent? The investors ought to be dancing on our tunes to invest in us!
You have to ask management why they wish to sell C shares at this level and why they value the stock here. It seems they are depressing the price.
I agree but some this stuff that’s been recently presented seems like the company is getting close.
My only concern is that if this truly is a miracle cure, where are the big boys and girls. How is this company sitting at 70 cents. I would think that companies like Merck would be all over this. I’m sure they have people / departments that look for promising treatments. The lack of run up in the PPS is perplexing.
Stick around for ten years and you can get all the promises made and broken.
“Use that opportunity to invest in a company with a dynamic and driven management team that takes accountability for their actions and do not play victim card or blame game. “
I am just waiting for new management. I had a discussion with Senti about when the Cs were shopped. To be honest these guys are probably shopping shares 24/7 365. To blame shorts after the reveal seems to stretch the envelope. What short would take a position without knowing the results that were pretty good? Especially for rGBM. What if the results were even better or they promoted the results properly. But you would look for a downturn if you had knowledge they were willing to sell shares at this current price. These leaders are not the financial wizards they are made out to be. They have hurt most shareholders and languished assets. That is just my take. Anyone disagrees it is an open forum.
Thank you for posting these solid facts.
Those that support the company seem to provide facts. Any facts to support your post. Thanks
Nice Danish Dude. Thanks:)
I have compiled a "what has happened in 2022" guide or in other terms "Let's pump it" for those who haven't heard of the phenomenons of reason, rationality, logic, that makes it possible to put forth information and thesis that are qualified with regards to being either uncompromising facts, or very probable.
Let's take a stroll down the 2022 memory lane and sum up, why the NWBO stock currently is the best stock investment since Gamestop around new years eve 2020, at this ridicolous price level.
Facts
January 9th.
The use of the external control arms trial design gets thumbs up by FDA, as the article "External Control Arms in Oncology: Current Use and Future Directions", gets printed in Annals of Oncology. 12 co-authors, among these dr. Richard Pazdur, ALL affiliated with U.S. Food and Drug Administration, also known as FDA.
January 11th.
AdventBio announces their new Cryostore and Freezer facility at Sawston.
January 23rd.
It is found out, that dr. Roger Stupp, the man behind The Stupp protocol, which became standard of care for the treatment of glioblastoma (GBM) since its publication in 2005, became an advisor to NWBO BEFORE September 26th. 2020.
January 27th, February 17 and 26th.
3 articles in british newspapers specifying the NWBO and AdventBio connection, with the later dedicated to do NWBO's bidding as a CDMO in terms of manufactoring and production.
When reading, one is not in doubt of the "mother-child" setup and what is AdventBio's main purpose.
A lot of talk going around regarding instability with financial institutions and hedge funds, specifically in the EU and Sweden.
Obviously there are broader implications that come with this, but I hope NWBO does not get affected in any way due to the turbulence of the financial markets:
https://m.investing.com/news/stock-market-news/blackrock-says-reducing-leverage-in-ldi-funds-2903030
The collapse in Credit Suisse's share price is of great concern. From $14.90 in Feb 2021, to $3.90 currently, markets are saying it's insolvent and probably bust. pic.twitter.com/RIBlqKLtvm
— Alasdair Macleod (@MacleodFinance) September 30, 2022
The Bank of England kickstarted QE this week due to pension funds potentially collapsing.
— Gold Telegraph ⚡ (@GoldTelegraph_) October 1, 2022
People forget that the Bank of England's bond portfolio losses are already £200 Billion.
Enjoy the show.
Deutsche Bank and Credit Suisse are tanking more right now than the financial crisis of 2009. There are so many market indicators that we are heading towards a major financial crisis. $DB $CB pic.twitter.com/AfkCX3yr9V
— James Melville 🚜 (@JamesMelville) October 1, 2022
Fascinating article Abeta! Thank you!
Will NWBO has ASM this year? Is that legal without annual ASM?
Re: None
Saturday, October 01, 2022 5:51:55 PM
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Sept 30 2022 - Glioblastoma recurrence reveals novel and targetable immunoregulatory drivers
NOTE: p means Primary
We, therefore, quantified the transcriptome and proteome of 134 patient-derived pGBM and rGBM samples, including 40 matched pGBM-rGBM pairs.
GBM subtypes transition from pGBM to rGBM towards a preferentially mesenchymal state at recurrence, consistent with the increasingly invasive nature of rGBM.
We identified immune regulatory/suppressive genes as important drivers of rGBM and in particular 2-5-oligoadenylate synthase 2 (OAS2) as an essential gene in recurrent disease.
Our data identify a new class of therapeutic targets that emerge from the adaptive response of pGBM to therapy, emerging specifically in recurrent disease and may provide new therapeutic opportunities absent at pGBM diagnosis.
https://pubmed.ncbi.nlm.nih.gov/36178522/
note - the above is the abstract and I don't know how to get to the whole article
other than paying about $40 bucks
Sidebar
2',5'-oligoadenylate synthase (OAS) is a class of enzymes induced by interferons and mainly encoded by the OAS1, OAS2, and OAS3 genes, which activate the potential RNA enzymes to degrade viral mRNA, inhibit viral protein synthesis and promote apoptosis in virus-infected cells. OAS3 is associated with breast cancer prognosis. However, the expression and prognosis of OAS3 and tumour-infiltrating lymphocytes in pan-cancer remain unknown. In the present study, we have systematically investigated and confirmed the role of OAS3 in tumour immune infiltration, immune escape, tumour progression, response to treatment, and prognosis of different cancer types using various bioinformatics methods. The findings suggest that OAS3 is aberrantly expressed in almost all TCGA cancer types and subtypes and is associated with tumour staging, metastasis, and prognostic deterioration in different tumours. In addition, OAS3 expression is associated with the prognosis and chemotherapeutic outcomes of various cancers. In terms of immune-infiltrating levels, OAS3 expression is positively associated with the infiltration of immunosuppressive cells. These findings suggest that OAS3 is correlated with prognosis and immune-infiltrating levels.
https://pubmed.ncbi.nlm.nih.gov/35592250/
Calling a link to a talk by liau a “pump” seems strange to me- have a great one Bobby!
Judge, But 50 dma has not crossed 200 dma (78cents). Why you call it golden cross now? I am confused.
well stated bio
1) Nowhere in my post did I say you said they were mismanaged. Why are you even asking?
2) Where did I say, repeatedly "all this silence is normal". These kinds of attacks are not NORMAL. These kinds of campaigns only happen to very particularly targeted companies. I agreed with you that yes, they had not had any quarterly calls
This is exactly what I said to the comment to which you just replied.
David, you are right I did not list the 200. I posted the 50 and the 100 bc they are on top of each other and we are imminent for 50 to cross the 100.
I called it the silver cross as a joke. But it’s a step in the right direction bc the 50 has to get over the 100!before it gets back over the 200. The 200 which is not listed is currently at 78
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“Now this is not the end. It is not even the beginning of the end. But it is, perhaps, the end of the beginning.”
~ Winston Churchill
Stylized Dendritic Cell featured on NWBO board since 2015
- Dr. Linda Liau, PhD, MBA, Professor and Chair, Department of Neurosurgery, David Geffen School of Medicine at UCLA
Clinical Trials
DCVax®-L to Treat Newly Diagnosed GBM Brain Cancer (NCT00045968) - Phase III (Double Blind)
UK (MHRA): DCVax-L to Treat Newly Diagnosed GBM Brain Cancer (EudraCT#) 2011-001977-13
DE (Germany - PEI): DCVax-L to Treat Newly Diagnosed GBM Brain Cancer (EudraCT#) 2011-001977-13
Expanded Access Protocol for GBM Patients with Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221 (NCT02146066) (Expanded Access)
Safety and Efficacy Study of DCVax-Direct in Solid Tumors (NCT01882946) - Phase I/Phase II (Open Label)
UK Clinical Trials - Study of a Drug (DCVax®-L) to Treat Newly Diagnosed GBM Brain Cancer
EU Clinical Trials for DCVax-L - Phase III
Dendritic Cell Vaccine for Patients with Brain Tumors (NCT01204684) - Phase II - at UCLA - Randomized (Open Label) testing DCVaccine with Resiquimod and DC Vaccination with Adjuvant polyICLC
Pembrolizumab and a Vaccine (ATL-DC) for the treatment of Surgically Accessible Recurrent Glioblastoma - Phase 1 (NCT04201873)
Dendritic Cell-Autologous Lung Tumor Vaccine (DCVax-L) and Nivolumab in Treating Patients with Recurrent Glioblastoma - Phase 2 (NCT03014804)
Dendritic Cell Therapy for Brain Metastases From Breast or Lung Cancer (NCT0368765) - Phase 1 - Collaborator: Mayo Clinic
Announcement of DCVax-L and Anti-PD-1 Monoclonal Antibody (Pembrolizumab) for Patients with Liver Metastases of Primary Colorectal Carcinoma Phase 2 Trial - November 17, 2016 - University Medical Center (UMC) of the Johannes Gutenberg University of Mainz
Cognate Bioservices - Owned by Charles River Labs
Website
Company Contact Info
Investor Relations:
Les Goldman (Company) (202) 841-7909 lgoldman@nwbio.com
Sign up for Northwest email list here (hit the subscribe to email list button in the lower right)
Company Headquarters
4800 Montgomery Lane, Suite 800, Bethesda, MD 20814 (240) 497-9024
NW Bio is developing cancer vaccines designed to treat a broad range of solid tumor cancers more effectively than current treatments, and without the side effects of chemotherapy drugs. NW Bio’s proprietary manufacturing technology enables them to produce its personalized vaccine in an efficient, cost-effective manner. NW Bio has a broad platform technology for DCVax dendritic cell-based vaccines.
Their lead product, DCVax-L, is currently in a 331-patient Phase III trial for patients with newly diagnosed Glioblastoma multiforme (GBM), the most aggressive and lethal brain cancer. This trial is currently underway at 69 locations thoughout the United States, Germany and the United Kingdom. NW Bio has also conducted a Phase I/II trial with DCVax-L for late stage ovarian cancer together with the University of Pennsylvania.
Their second product, DCVax-Direct, is currently in a 60-patient Phase I/II trial for direct injection into all types of inoperable solid tumor cancers, with trials currently being conducted at both MD Anderson Cancer Center in Texas, as well as Orlando Health in Florida.
They previously received clearance from the FDA for a 612-patient Phase III trial with its third product, DCVax-Prostate, for late stage prostate cancer.
DCVAX Survival Stories & Testimonials
Alice - Metastic Merkel Cell patient from Florida - ASCO 2018
Brad Silver - GBM patient from Huntington Beach, California - ASCO 2018
Sarah Rigby - GBM patient from Hong Kong - ASCO 2018
Kristyn Power - daughter of GBM patient from Canada - ASCO 2018
Kat Charles - GBM patients from UK - ASCO 2018 - as related by her husband Jason (Kat's Cure)
Prospective patients may contact NW Bio at patients@nwbio.com
UCLA Jamil Newirth DCVax-Patient Video - 2015
Allan Butler Video - National Geographic Vice President - DCVax-Direct patient from Phase 1 Trial with Pancreatic Cancer
NWBO - Patients Sunday Dennis and Jami Newirth - Enrolled at UCLA - Vimeo, Uploaded approx. May 2015
NWBO - Vaccine Helps Keep Brain Cancer Patient Alive (Jennifer Sugioka) - NBC Channel 4, Southern California, February 24, 2015
NWBO - National Geographic's Allan Butler Stage IV Pancreatic Patient using DCVax-Direct at MD Anderson
NWBO GBM Brain Cancer Survival Story of Mark Pace
Presentations
UCLA Agreements
Prostrate
DCVax-Phase II
DCVax-Booster
Upcoming Events
Videos
Linda M. Liau, MD, PhD, MBA - April 24, 2019 at University of Washington, Neurosciences Institute
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