Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
My bad, somethings up this thing is starting to move fast!!!!
Relax dude, the market is closed today... Good Friday
No trades today? I feel a meltdown in the makings!!!!
Stifel Calls Aratana Therapeutics a 'Buy' on Entyce, Galliprant Optimism
https://tinyurl.com/y8dbyoux
Veterinarians and other creepies shorting PETX might could get some real hurt despite the hefty down draft today.
I thought Entyce was badly overlooked but Galliprant gets a gold star from us and wonderment that Eli Lilly is not apparently developing the human EP4 antagonist.
It was a surprise to me when PETX bragged they owned all the rights to the drug's mechanism of action against osteoarthritis. Our border collie/lab mix that was all but on her deathbed is bouncing around in the snow like a pup while my is very badly crippled.
Our mail order supplier rates even a generic higher - which seems insane.
Quite possible the piprant that was modified to keep the joints lubricated with no apparent effect on the arthritis proper will harm humans but I can find no evidence anyone is looking.
PETX's new Japanese partner also has an EP4 antagonist. No difference was specified though it was included in licensing.
Best, Terry
From transcript of PETX teleconference on 4thQ results 3/14/18:
https://tinyurl.com/yaacme8b
Last month and earlier this month, we attended the two largest trade conferences in the US veterinary industry, VMX in Orlando and Western Vet in Las Vegas. Based on an aggregate number of clinics that we believe have purchased NOCITA, Galliprant and/ or ENTYCE, we believe that a large majority of veterinary clinics in the US are already using a therapeutic developed by Aratana. We believe this is quite remarkable for any company to gain acceptance of one or more of its therapeutic products by approximately two-thirds of customers in an industry within a year.
That's what St. Peter said and surely with a name like that he wouldn't lie would he?
The disconnect between that statement and a casual reading of the financials is probably accounted for by the usual promotional expenses for introduction of a new drug, the lag between wholesale stocking and retail sales and even, perhaps, what seems to me unusual accounting efforts to adapt to real world conditions with a strain on resources.
ENTYCE, capromorelin oral solution is the only FDA approved therapeutic for appetite stimulation in dogs. ENTYCE mimics ghrelin, the naturally occurring hunger hormone. It is administered once daily and it travels from the mouth to the stomach then into the blood up to the hypothalamus in the brain where it stimulates eating behavior. We believe that millions of dogs present to the veterinary clinics in the US for inappetence each year.
An overlooked biggie IMO.
In December 2017, the USDA's Center for Veterinary Biologics granted Aratana conditional licensure for canine osteosarcoma vaccine...In the past few weeks, Aratana sold its first dose of AT-014 to a study site.
GRRR!
That extended study is an atrocity.
FACT: Way back when I was younger and had much to learn about the obstinacy, ignorance and stupidity of regulators and their fawning supplicants, an idealistic scientist managed to get FDA approval for a vaccine adjuvant treating surface tumors on horses. Dr. Ribi's detoxified cell wall skeletons had much in common with Prof. Paterson's superior live Listeria vaccine adjuvant but didn't have a deadly antigen like HER2/NEU.
PETX recognized ADXS' spurious franchise/construct for the therapeutic vaccine it is and surely the threat of the HER2 antigen that has been documented in killing a handful of women being treated for breast cancers is of minor concern in dogs with an osteosarcoma having a near 100% fatality rate. I have found no reliable (nor even unreliable) statistics on the matter.
Anyway good conference call with a lot of hard questioning.
Best, Terry
“Takes all kinds actually”
How thankfully right you are...
I expect you probably have a academia background
Sorry, Biotech, you missed by a mile. I couldn't survive in the authoritarian academic world. I am at a loss to explain the reason for its singular success in basic research.
Whether it was the unschooled physicist Ovshinski whose scientific discoveries and inventions are still changing our world or a man like Einstein who spent his life in academia but dreamed of being a plumber with his hatred of the system, few scientists are enamored of dictatorial rule.
I was fascinated with a Russian "sugar" scientist whose deep science was first experimented with at Moscow University where he was a professor. In America he was CSO of a biotech developing his science until he tired of the bitter warfare and took a professorship at Yale where he gets to hear Ivy League insults fired at his wide-ranging scholarship, most notably his theory that the Neanderthals evolved in Europe where nearly all evidence of their previous existence resides rather than in Sub-Saharan Africa where a non-human primate is claimed to be mother of us all. There is no sign whatever of even Neanderthal genes of the big-brained, family-loving humans in southern Africa that white supremacists set so much store by.
Dr. Frost earned his billions from his research and genius rather than duplicity. He is no academic either but recognizes its value.
Takes all kinds actually.
Take care.
Terry
Terry Hallinan, I expect you probably have a academia background as I don’t sense your engagement in business metrics or results. That certainly is commendable, but the stock market typically better awards companies with measurable results. At this stage in their growth, PETX should be growing revenues at a much higher rate (30-50% q over q )as it is from a very low base. I think it will get there but Mr Market expected more. And there’s that pesky detail that they have a pretty good slug of debt that they are paying on.
You mentioned a individual that I had forgot about from many years ago. P. Frost. In Miami, P. was recognized as one of the biggest crooks to run a biotech company in the SE US. That company was Ivax. Check out the stories from 20-30 years ago. And more recently, here is a recent story about P. that shows nothing has changed..
https://www.bizjournals.com/southflorida/news/2017/08/10/billionaire-phillip-frost-defends-his-biotech-firm.html
Sell off was technical. But this stock is a shorts target too. They have been shorting it off and on for 2 yrs.
At $4.50 it was Overbought technically. Now the 3 day rsi is about 16. If bio’s (XBI & IBB), go green tomorrow this could go green a bit. I flipped it today. Then bought again at 3.80 eod. Will be bidding lower in the morning and watching for direction
Hard to understand today's sell off.
Entyce guidance was soft, sounds like next ER they will report less than or equal to 1.3 million in Entyce sales. Management has continued to say how Entyce has exceeded their expectations.
But Galliprant and Nocita are rocking with serious revenue growth.
$15 million milestone payment expected to trigger in Q4 this year.
Biotech_researcher,
Terry Hallinan, I expect with the Q4 results just released, you better understand my concerns over the last 6 months?
Right and wrong are relative to objectives and results.
Does it surprise you that some raging bulls love what PETX has accomplished while some others are soured on the same record?
All depends on which end of the telescope you are looking through.
As an incredible example, Warren Buffett advises that one should not be discouraged if a recent purchase is quickly cut in half by the market but compare the incomparable master of the stodgy cash cow to Warren's friend Phillip Frost, the Warren Buffett of Biotech, that has a decade of abominable price results for his final project - Opko.
I have lived through unique achievements that seemed early on pure chicanery like that of unschooled physicist Stanford Ovshinsky
https://tinyurl.com/8vpv8jr
who jealously boasted of wearing silk suits from Hong Kong and handmade Italian shoes while threadbare scientists read their scholarly papers to each other from podiums from which he was excluded because of a total lack of academic credentials.
Over a couple decades Ovshinsky and his investors in an unprofitable corporation became very wealthy while scoffers like myself prided ourselves on not being fooled by such a clown.
Obviously, Biotech Researcher, it would be churlish to claim any prospective success for PETX remotely like that of Ovshinsky's
Energy Conversion Devices but I think PETX has already accomplished a great deal and so do others:
https://tinyurl.com/ya4bc8us
https://tinyurl.com/y8yw54y4
Best, Terry
Terry Hallinan, I expect with the Q4 results just released, you better understand my concerns over the last 6 months?
Beyond the horizon
From PETX Full Year 2017 Financial Results
https://tinyurl.com/yaduuao2
In February 2018, Aratana announced an animal health research and development collaboration with AskAt Inc. The collaboration includes an option agreement for multiple therapeutic candidates with potential in pain, allergy and cancer, as well as exclusive, worldwide rights to develop and commercialize AT-019, a potent and innovative EP4 receptor antagonist therapeutic candidate with potential in pain, inflammation and other indications.
The rest of the voluminous report looks good to me but this holds particular interest for me and perhaps for Aratana's near future.
Notice the "potent and innovative EP4 receptor antagonist therapeutic candidate" above in the Japanese collaboration and then look at mention in this description of Galliprant that PETX brought through FDA licensing:
It specifically blocks the EP4 receptor, the primary mediator of canine OA pain and inflammation
https://www.galliprantfordogs.com/vet
What does this mean?
- I don't know what it means exactly but blocking that EP4 receptor in dogs relieves the pain and inflammation of osteoarthritis while not preventing the natural lubrication of joints like NSAIDS.
Then going way beyond:
the very recent 3D modeling of the human EP4 receptor
https://tinyurl.com/yb6rpre9
Hey, this is a leap way out of bounds but something I mean to look into because my wife is also terribly crippled by osteoarthritis.
Best, Terry
Biotech Researcher,
So, PETX received $5.4-$2.2 or $3.2 million of actual product revenue from Galliprant in Q3 2017, so on March 14th, we will have another data point on Galli’s organic growth rate. It should at least double, I hope..................
Hope has even fled the White House again. I don't put much store by that purported virtue but I would be very disappointed by a decline in retail sales which are not directly related to inventory sales.
In our case we had a devil of a time getting any Galliprant tablets because we first needed a prescription from a vet who knew nothing at all about the drug for our 7-year-old mixed border collie and then we quickly found we couldn't buy the drug anywhere in our area.
Happens when you live in the sticks.
There was a break because of another snafu after the first month's supply was used and the dog quickly became a cripple again.
Long term questions remain to be answered in the - ahem - long term and that is even now of great interest to our vet with his "animal hospital."
Galliprant as a first-in-class piprant does not inhibit the production of many housekeeping prostanoids that maintain homeostatic functions.
It specifically blocks the EP4 receptor, the primary mediator of canine OA pain and inflammation1
https://www.galliprantfordogs.com/vet
Longterm safety questions remain.
How many many painfully crippled dogs from osteoarthritis like ours in our area are romping in the snow like a young pup.
- None that anyone knows about.
Even our clinic is waiting on answers.
In humans a ramp-up period for new drugs is much faster than in America but still can take 2 or 3 years to go mainstream.
I would guess it would be much the same with animals.
JMO.
Best, Terry
So, PETX received $5.4-$2.2 or $3.2 million of actual product revenue from Galliprant in Q3 2017, so on March 14th, we will have another data point on Galli’s organic growth rate. It should at least double, I hope..................
Aratana recorded $5.4 million in revenues during the third quarter of 2017 related to GALLIPRANT® (grapiprant tablets), including $2.2 million in GALLIPRANT licensing and collaboration revenue from Elanco Animal Health, a division of Eli Lilly and Company. Third quarter 2017 GALLIPRANT licensing and collaboration revenue included a $1.0 million one-time payment for the transfer of manufacturing responsibility to Elanco. The remaining $1.2 million of GALLIPRANT licensing and collaboration revenue compares to $0.8 million in the second quarter of 2017.
When Aratana can exhibit a solid ramp up in sales, this will be golden.
Others, most notably Alan Abelson [editor of Barron's when it was worth reading, have pointed those are the best times to take profits from development stage corporations. The most dangerous time, opined the very witty Abelson, was when such corporations turned a profit.
Abelson wasn't always right - a perennial whipping boy was Amazon - but he was always logical.
JMO.
Best, Terry
Aratana still has tiny sales. When Aratana can exhibit a solid ramp up in sales, this will be golden..
Aratana Therapeutics Expands Therapeutic Candidate Pipeline
https://tinyurl.com/yac7b7zm
But don't nobody much care.
Price goes up so somebody is noticing.
I would be in hog heaven had I an extra dime to spare.
The darkness in the market and the land is far more understandable than the previous crazed response to fiscal folly in government and blue chips.
What I do know is Dixie [our dog] is alive because of Galliprant, sales are moving forward, new markets are opening, new therapies are on the way and nobody much cares near as I can tell.
What more could a stockholder ask?
Best, Terry
When PETX pulled the secondary, that is usually a share price destroyer for awhile as everyone and their uncle knows it is coming. Probably should have let it fly and let the recovery begin right after.
Maybe you are right, Biotech Researcher, but selling at giveaway prices burns forevermore as I see it.
During a now forgotten earlier real estate collapse, the inlaws had my wife's grandmother's house on their hands with the usual quick buck artists offering a few thousand for houses formerly going for hundreds of thousands.
Despite screams of pain from other heirs they improved the property with a view to renting it if necessary to get a decent price from a recovering market. As it turned out, the particular energy crisis ended in the twinkling of an eye as the imaginary Arab Oil Boycott was exposed as pure fraud.
PETX has done it right IMHO but not nearly as well as scientist and financial wizard Mike West who is growing cash and IP at a furious pace with a constellation of beyond futuristic biotechs.
At an annual meeting in NYCity an angry shareholder hogged the floor crying over giveaways. Would that all others could get rich with such charity.
[I have deliberately omitted any link to avoid any shoutout to an extremely risky situation but an interested party can easily find and judge for himself.]
Getting back to PETX the fund raising has not ended but has only avoided the ugly headlines with a more measured private means.
Good on them, I think, but we are deeply biased by what Galliprant has done for our dog that was in a desperate situation.
We can only buy Galliprant mailorder with a prescription and here is a downbeat comparative assessment from our supplier even vs. a generic [note, for a primary example, the "stiffness" rating}:
https://tinyurl.com/y9737fa4
Huh? What? We figure our little darlin' would be history without Galliprant. What's going on?
Very simple:
The Empire strikes back. Disruptive technologies are particularly unappreciated in our newly plutocratic economy IMO. Eli Lilly will overcome as a prominent part of the oligarchy.
JMO as always.
Best, Terry
When PETX pulled the secondary, that is usually a share price destroyer for awhile as everyone and their uncle knows it is coming. Probably should have let it fly and let the recovery begin right after.
BlackRock Inc. has filed an amended 13G/A, reporting 5.9% ownership in $PETX
https://fintel.io/so/us/petx
The Truth About Galliprant
Abstract
There are five active prostanoid metabolites of arachidonic acid (AA) that have widespread and varied physiologic functions throughout the body...
http://onlinelibrary.wiley.com/doi/10.1002/vms3.13/full
Reportedly there are some nerds who lap up this kind of stuff up like men lap up por...
Uh, I think some interested in their investment might bear to read a bit of this stuff because there is a taste of real scandal here:
Prostaglandin E2 (PGE2) is a prostanoid that serves important homeostatic functions, yet is also responsible for regulating pain and inflammation. PGE2 binds to four receptors, of which one, the EP4 receptor, is primarily responsible for the pain and inflammation associated with osteoarthritis (OA). The deleterious and pathologic actions of PGE2 are inhibited in varying degrees by steroids, aspirin and cyclo-oxygenase inhibiting NSAIDs; however, administration of these drugs causes decreased production of PGE2, thereby decreasing or eliminating the homeostatic functions of the molecule. By inhibiting just the EP4 receptor, the homeostatic function of PGE2 is better maintained.
In plain words, the angry but honest cowboy in Minnesota has been lied to by those with a vested interest in inferior drugs for treating osteoarthritis in dogs and hopefully soon in humans.
PETX was contracted by Eli Lilly to gain veterinary approval of the piprant drug Galliprant for dogs prior to Eli Lilly seeking FDA approval for human use through its own R&D.
It is not a cure. It is a maintenance drug. But it is a grand thing I tell you from our own experience as an intermediate measure before actual cures are developed.
Anybody tells you Galliprant is an NSAID or steroid is lying to you or a victim of false propaganda.
What sociopath would do such a thing?
Ask your mommy if you really don't know.
Best, Terry
"Galliprant is working very well for Dixie." wrote the vet on her records at the animal hospital.
She didn't mention all those NSAIDS that don't work so well for hardcases like border collie mixes craving excitement.
How I would love to see a competitive clinical trial.
Best, Terry
Galliprant is giving dogs a new lease on quality of life.
Better than that, Blue.
We firmly believe our darlin' dog would be incinerated or pushing up daisies without a very complex new drug that Eli Lilly contracted PETX to get FDA approval because of PETX's unique status. Lilly is looking to bring the piprant to market for humans.
Best, Terry
Bottom line is Galliprant is giving dogs a new lease on quality of life. Google Galliprant reviews. 75% re-order rate. Over $20Mil in milestones coming in 2018. Undervalued imo.
https://seekingalpha.com/article/4139298-aratana-therapeutics-investors-barking-wrong-tree
Here's what I know and you can discard some or all but you'll need a different (almost any) subject to educate me.
I believe your expertise and I would prove myself a far bigger fool than I am were I to deny it. I am trying to learn and am not succeeding.
Dasuquin and Dasuquin Advanced are not the same.
You yourself pointed out Dasuquin was for puppies. I don't know what nutrition puppies get from avocados. Do they have any? Dasuquin Advance is for old dogs like me that just think they are pups. Uncompensated researchers seem to agree.
Beyond that Galliprant is not, not, not a pain medication per se. It is intended to keep the synovial fluids flowing which NSAIDS shut down. Pain medication is suggested by some as a supplement and we considered it and decided against it - to do nothing to hinder lubrication.
Happily there is no indication of pain now but there was during a time when we had no piprants for about 10 days and the pains returned and stiffness returned. Took another week or two then for the the current restricted movement to return. The vet had told my wife the arthritis in the chest front joints appeared the most severe while we had concentrated on that one hind leg that seemed useless.
Again I am confounded by the huge gap in appraisals you present but we both appear blind men examining an elephant.
"A new class of drugs called the piprants are being widely studied and one such drug is now available for the treatment of
osteoarthritis associated pain in dogs (Grapiprant). Grapiprant is a selective antagonist of the EP4 receptor, one of the four
prostaglandin E2 (PGE2) receptor subtypes. There are likely to be fewer unwanted side-effects with this class of drug because the
COX-1 and COX-2 pathways are not affected"
That is from this article:
"Acute and Chronic Pancreatitis: What to Do?
Elizabeth Colleran, DVM, MS, DABVP
Chico Hospital for Cats
Chico, CA"
If you don't have an accursed Toshiba laptop with weird exotic bugs that computer experts have invigorated and further supplemented for me, you could probably get the article and URL or you could call Lizzie if you don't mind talking about cat medicine for dogs and people.
I go to great lengths, Buck, to find anything that will expand and confuse the simplest questions and my computers always hate me for it.
Hope it's not contagious.
I'd think it'd be hard to get kicked there sitting on a horse. After thousands of horses and many of them kicking, biting, standing on me I do feel your pain and have also been kicked there (and everywhere else). I currently live in MN which I consider an IQ test and since I stayed here I failed.
As I said; pain management in dogs has been a focus of mine for years so there aren't many published studies I haven't read nor meetings I haven't attended. Here's what I know and you can discard some or all but you'll need a different (almost any) subject to educate me.
Many vets use Dasuquin first as no side effects and some dogs do improve on it. It is classified as a nutriceutical which means they can make claims without proving anything and are almost never tested for content. At one point a university tested 60 different brands with similar ingredients and only 3 had anywhere close to what the label claimed. Some had none of the claimed ingredients. Whether the glucosamine, chondroitin, avocado do anything has been debated for years: https://www.ncbi.nlm.nih.gov/pubmed/16999714
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356289/
MSM has been proven ineffective in dogs. The NSAIDS are a whole different ball game. Much more effective but some side effects that can be deadly in a very few dogs so occasional blood tests warranted.. Previcox slightly safer as only affects 1 Cox instead of 2. Every dog I've treated I start on dasuquin and if or when no effect switch to NSAIDS. You will always see remarkable improvement at that time. Different NSAIDS will work better on different dogs. Recently it was discovered that any side effects will usually occur in first 2 weeks. Current thinking is better to treat early and longer instead of waiting for arthritis to progress too far.
Enter Galliprant with very limited side effects and very good safety. Now all it has to prove is that it can be as effective. My guess is the new trail of treatment will be dasuquin, galliprant, classic NSAIDS. BY THE WAY; WEIGHT LOSS, FISH OIL AND EXERCISE, ESP SWIMMING DOES WONDERS FOR THESE GUYS. Apologize to you and everyone else for length but you baited me. 8<) And thank you for your service.
I expect there was something else amiss with your bank account/login process
And a million others?
All I can tell you is that very day was a bad day for many others.
Coincidence?
- Could be, of course, but I am not a big believer in such coincidences.
This is just a Google list of finds about the purported insecurity of its own gmail:
https://www.google.com/search?q=gmail+breakin&ie=utf-8&oe=utf-8&client=firefox-b-1-ab
Could it be super secure now?
- Wouldn't surprise me.
I agree Juno is junk but when yor're in deep water with sharks swimming around you tend not to be choosy.
I note you warned me and thank you for it.
Best, Terry
My wife is Swedish too. Condolences. 8<)
a university orthopedic guy was one who told me stick with previcox.
The professor, or whatever he was, may have given the best advice but the following is scholarly compendium of recommendations:
When people suffer with arthritis or bone and muscle pain, we generally tend to stop at our local pharmacy and reach for pain ... generic forms), Deramaxx (Deracoxib), Previcox (Firocoxob), Metacam (Meloxicam ~ available for Cats, too), and. EtoGesic ... Dasuquin Advanced is a suitable choice as well
This is from a .pdf file consisting of a lengthy compendium of various treatments for older dogs' arthritis that has Dasuquin Advanced on a par with previcox. I could not get the damn thing to post on my browser.
Maybe our vet was just attracted to a quack remedy but I gather otherwise.
Appreciate your source and interest.
A horse expert in Texas? Will wonders never cease? Where you from? Illinois like John Wayne?
When I was very young a horse kicked me very near the most vulnerable spot any male can be kicked. No, not the head, man. Men don't use their heads much. But she didn't mean it. She was trying to kick the horse I was sitting on. Though my horse was the greatest horse anybody ever had, I learned a lot about why I should do less dangerous things with handsome rewards than being a cowboy and so I went to Vietnam.
Thank you for still talking to me.
By the way back when the FDA approved a vaccine adjuvant - now known as MPL as it blazed back into the headlines recently as the power behind an effective malaria vaccine along with a rootbeer flavoring [saponin]- used alone for treating sarcoid cancers on horses. The "vaccine" was eventually abandoned because it was too messy without an antigen as with an old bladder cancer vaccine.
If you think I have a focus on vaccines, you may be on to something. We all have our biases.
By the way I could only dredge up some old memories with Google's browser breaking proprietary boundaries as above and so you will have to trust me because I hate Google.
Best, Terry
My wife is Swedish too. Condolences. 8<)
I expect there was something else amiss with your bank account/login process than gmail, if you know what I mean... Juno is at this juncture is junk......
Thank you very much, biotech researcher, but I had gmail for exactly one day and had my bank occount cleaned out. I think it no coincidence that lots of others got burned that very day. We are still taking hits from that.
Again, I appreciate your sympathy but I think you probably understand.
Best, Terry
Terry, re: spam email, may I suggest an email client for you that is not from the previous decade?? Juno is so yesterday, and has little technical support/product enhancement. GMAIL is one of the best, and I receive ZERO spam emails....
Do NOT go into Texas and call anyone a drugstore cowboy. 8<)
I married a Texan and they know what they are. They surprised me when we went to cockroach haven. They openly discussed that the mandatory great-great-great-grandmother Cherokee born on a Cherokee reservation may have been a Cherokee slave. Actually my wife is half Swede and they know what they are too which is why my son insists he is Irish.
With that out of the way:
The cancer drug may be a big deal Problem there is; if I read the research right the test also included amputating the leg and many owners have a real hard time doing that. And that's if they ever get it to market.
Affected legs are usually amputated for osteosarcoma and then the dogs nearly always die anyway. The HER2 vaccine was first given to dogs that were inoperable but now has been given to dogs instead of amputation. The USDA's ignorance of therapeutic vaccines has delayed full approval but even they couldn't avoid giving conditional approval finally.
The reason dogs were probably trialed first is because the HER2 antigen can be a killer and vaccines are far more powerful than other drugs. Similar story with Galliprant. Piprants are a very complicated drug and can cause inflammation as well as fighting it.
Don't believe me?
Herceptin has been a huge success as a breast cancer drug but that HER2 targeted is expressed by many organs. Herceptin killed some women with breast cancer because it also killed some heart cells expressing the HER2 oncogene.
https://tinyurl.com/y6v84sz8
Investors in the HER2 vaccine just can't understand why even JNJ isn't rushing to lease the vaccine for humans but now we both know why.
Best, Terry
Terry
Very glad to hear it's helping your dog. As I said; all reports I've obtained have been ; yes, helpful but not nearly as effective as some NSAIDS. I've talked to probably 5 or 6 vets and they've all said basically the same. Hopefully reports will get better as more of it is used. Since this sounds like the first med you've had to use you have nothing to compare it with and no need to as long as it's working. Pretty much all arthritic dogs progress at variable rates and if your pup is just starting to need treatment you would expect galliprant to handle that. I have a Golden therapy dog that's been on previcox 7 months and at some point i'll probably try it on him but a university orthopedic guy was one who told me stick with previcox.
If you wonder why I don't use my own client's experiences it's because I specialize in horses; hence all my broken bones and ruined joints. I always have rescue dogs and therapy dogs and every one of them has developed arthritis, ACL tears etc so pain management is about the only area in canine medicine I feel competent in and have done a ton of research. I love my dogs.
Going to a meeting on specifically this subject mid February so I'll ask the speaker/specialist his opinion and if any value I'll let you know.GOOD LUCK WITH YOUR PUP AND I HOPE IT WORKS FOR A VERY LONG TIME.
I got into this for Galliprant. If it works as good as current NSAIDS without side effects it'll be a huge money maker. Problem I've seen is all my vet friends (I am one) describe it as helpful but less effective than previcox or rimadyl.
I am astounded by your reply, Buckboard. I believe you are sincere and see no reason to pursue the matter of PETX's decision to withdraw the aborted offering.
To avoid any possible misunderstanding, I will give you the name of the animal hospital in Utica, NY, the vets we are dealing with there and other matters after a Thursday appointment for a checkup. We now get our grapiprant tablets ["Galliprant"] by mail order from PetMed.
Dixie is our 7 or 8-year-old, 80-lb border collie-lab mix rescued from a shelter.
We first took serious notice of a scary problem of Dixie keeping one rear leg off the ground or dragging it as a useless appendage. Her pain and some distress was obvious. I had to think OSTEOSARCOMA from my limited knowledge of that horror but truthfully osteoarthritis is as deadly for dogs.
The vet at the animal hospital told my wife of the clear evidence of arthritis in front legs and chest. The odd motion in running persists but the old high spirits are back and she easily outdistances our black german shepard running. No x-rays have been taken to date. She prescribed Dasuquin Advanced, which did seem somewhat helpful but not remotely like Galliprant that I had to go on an odyssey to obtain. We needed a prescription and no local vet knew anything about it.
We both believe Dixie would by now be long underground or incinerated without the piprant. An unfortunate delay in getting a prescription to the 1st mail order supplier saw the return of the symptoms of osteoarthritis full force until we got more tablets. Galliprant is no cure but again it works wonders for now for something over $200/3 months supply. I surely understand that would be too high a burden for some dog owners.
My email is terryx@juno.com and I will be happy to answer any inquiries but I suggest waiting until at least the end of the week to absorb any word we get from the vet. Should anyone send an email to me, I suggest a notice here because the volume of junk email is overwhelming.
Best, Terry
TERRY
You seem like a decent, rational person which is pretty rare on message boards 8<)
My reference to trading would have been better stated as involved in the stock market. I keep about 7% of my investments in trading. The rest are long term and conservative. I've been in and out of PETX twice and currently out. Yes, I've seen offerings withdrawn but not the same day. Maybe I've been lucky but to me it was the stupidest management move I've ever seen. Guess we'll just continue to disagree on that.
I got into this for Galliprant. If it works as good as current NSAIDS without side effects it'll be a huge money maker. Problem I've seen is all my vet friends (I am one) describe it as helpful but less effective than previcox or rimadyl. Clients they have on either of those drugs when switched to galliprant are disappointed. Maybe the next ten vets I talk to will love it. Hope so as have a dog of my own I'll eventually try it on.
The cancer drug may be a big deal Problem there is; if I read the research right the test also included amputating the leg and many owners have a real hard time doing that. And that's if they ever get it to market. One caution to you too buddy: Do NOT go into Texas and call anyone a drugstore cowboy. 8<)
Morning, Buckboard.
Did you ever wonder why the buckboards we rode on when we were young bucked like a stallion mustang with no intention of being tamed?
Maybe you are still riding buckboards and doing things I wish I had never stopped doing but the original buckboards had springs. At least in the West that's so far west we called Coloradans easterners and Tex was always a drugstore cowboy that my older sisters said wouldn't know a horse from a billy goat.
PETX is a real pet biotech. I know of no other like it though there are pretenders like Eli Lilly's Elanco that PETX was contracted to get FDA approval for its osteoarthritis wonder drug. Galliprant is most assuredly not just another NSAID as claimed here. All NSAID's interfere with natural lubrication of the joints, which Galliprant does not.
I've traded stocks 40 years
Maybe that trading is your problem, friend. I traded off some huge winners in nearly 60 years of buying stocks but maybe you are a lot smarter and quicker than I am.
A caution, Buckboard.
I have seen companies many times announce a public offering and then pull back when the reaction is unpleasant. PETX is in the biotech business for R&D and sales of drugs for pets, not stock sales like brokers.
Did PETX blunder in announcing a public offering of new shares and then withdrawing it when the market reacted very badly?
- I don't think so but I accept your opinion as quite rational and perhaps the right one. Maybe my brains got jostled too much by buckboards and a horse kicking me near a lot more vital spot than what passes for my brain box.
Best, Terry
We're only discussing the science.... talking about PETX getting AT-014 conditional approval and the other company which AT-014 science belongs to....
PS
I didn't mean this company is failing; just it's management
Maybe I'm misunderstanding what you guys are saying but are you stating PETX has good management??? Hard for me to understand if so as I've traded stocks 40 years and have NEVER seen a company announce an offering and cancel it same day. Clown act from a failing circus.
unfortunately none of this is reflected in PETX share price....
My feeling is price and value are more independent variables than even so much dependent. Both are judgemental.
Imagine the Baghdad Stock Exchange when the "shock and awe" bombing campaign began. As best I can recall, the trading in the first days of the campaign continued until all the power went off and the exchange never opened again.
How much calculation of income, cash flow, asset values and other financial measures occurred while the bombs and rockets flew?
In reality it's hard for me to imagine what Baghdad Stock Market participants ever used to judge the worth of a stock but there are active stock markets in totalitarian states like China where the generals have huge sway on corporations' health and wealth.
I talked personally to a geneticist and businessman whose father made him CEO of a dummy corporation and sent him to prospect for possible partnerships or even purchases of Chinese high technology companies.
Junior reported to Daddy Warbucks science was first class but there were serious impediments like the need to provide fine employment for generals' worthless relatives.
There is timing and fads and emotion and all manner of things involved in the price of a stock while value is highly variable as well with vastly different opinions from one analyst to another.
It's a jungle out there, man.
JMO.
Best, Terry
Good post, unfortunately none of this is reflected in PERX share price....
GALLIPRANT® (grapiprant tablets) Named Best Companion Animal Product for 2017
https://tinyurl.com/y8smrkuw
This is the fourth consecutive year Aratana has been honored with an award from Animal Pharm.
No word on who might be a hefty funder of Animal Pharm but I bet I can guess one.
Best, Terry
Agreed, thanks and I like your last statement:
"an erstwhile giant partner on its way is melting away under atrocious management, while PETX is really showing its worth IMO."
post says news in India... what does this mean?
Traderbx,
I like to provide links to support what I post when appropriate.
Since I got the news on my broker's website, I simply used a search engine to find other sources and got some goofy ones including Bloomberg only interested in its own promotion.
I was frankly surprised at an Indian news source releasing such news to a worldwide audience including places like Somalia and Laos in their own languages.
Don't suppose there are many big buyers of PETX in those countries but India itself is one possibility.
Years ago I went to an annual meeting where a very unhappy stockholder had flown in from India to ask where all his money had gone when the management flew away on golden parachutes. We had even passed a billboard advertising the remains of an entire subsidiary - desks, chairs, computers, etc. - to be sold at auction.
The Indian was quite humorous besides his obvious pain and the young tyro CEO let him dominate the meeting and answering all questions as best he was able.
We hope the Indian kept his stock. We took the pennies left. I believe it has a quite respectable price today.
Anyway, Traderbx, an erstwhile giant partner on its way is melting away under atrocious management, while PETX is really showing its worth IMO.
Glad the whole world can know.
Best, Terry
Terry I followed your link, the post says news in India... what does this mean?
The news of European marketing may open another swell opportunity for another partner, Advaxis, that used to jostle PETX a lot:
https://tinyurl.com/y89a958m
For clarity to any not in the know, Tony Lombardo is the temp CEO hired to dump Advaxis on the market. PETX has proven Advaxis has splendid science but don't bother to tell the "management" of Advaxis which fired a very successful CEO.
PETX has proven its worth in spite of heavy incoming flak itself IMO.
Best, Terry
Followers
|
24
|
Posters
|
|
Posts (Today)
|
0
|
Posts (Total)
|
438
|
Created
|
08/09/13
|
Type
|
Free
|
Moderators |
Corporate Headquarters
1901 Olathe Blvd
Kansas City, Kansas 66103
(913) 951-2132
Other Locations
200 Clarendon Street; 54th Floor
Boston, Massachusetts 02116
(617) 425-9226
Business Development Contacts
Julia A. Stephanus
Chief Commercial Officer
(913) 951-2139
juliaastephanus@aratana.com
Erick J. Lucera, CPA, CFA
Vice President, Corporate Development
(913) 951-2136
erickjlucera@aratana.com
Investor and Media Contacts
Tiberend Strategic Advisors, Inc.
35 West 35th Street; 11th Floor
New York, New York 10001
(212) 827-0020
Investors - Joshua Drumm, PhD
(212) 375-2665
jdrumm@tiberend.com
Media - Andrew Mielach
(212) 375-2694
amielach@tiberend.com
Transfer Agent and Registrar
American Stock Transfer & Trust Company, LLC.
(800) 937-5449
Volume | |
Day Range: | |
Bid Price | |
Ask Price | |
Last Trade Time: |