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Re: Buckboard post# 350

Monday, 01/22/2018 7:40:35 PM

Monday, January 22, 2018 7:40:35 PM

Post# of 438
Do NOT go into Texas and call anyone a drugstore cowboy. 8<)

I married a Texan and they know what they are. They surprised me when we went to cockroach haven. They openly discussed that the mandatory great-great-great-grandmother Cherokee born on a Cherokee reservation may have been a Cherokee slave. Actually my wife is half Swede and they know what they are too which is why my son insists he is Irish. smile

With that out of the way:

The cancer drug may be a big deal Problem there is; if I read the research right the test also included amputating the leg and many owners have a real hard time doing that. And that's if they ever get it to market.

Affected legs are usually amputated for osteosarcoma and then the dogs nearly always die anyway. The HER2 vaccine was first given to dogs that were inoperable but now has been given to dogs instead of amputation. The USDA's ignorance of therapeutic vaccines has delayed full approval but even they couldn't avoid giving conditional approval finally.

The reason dogs were probably trialed first is because the HER2 antigen can be a killer and vaccines are far more powerful than other drugs. Similar story with Galliprant. Piprants are a very complicated drug and can cause inflammation as well as fighting it.

Don't believe me?

Herceptin has been a huge success as a breast cancer drug but that HER2 targeted is expressed by many organs. Herceptin killed some women with breast cancer because it also killed some heart cells expressing the HER2 oncogene.

https://tinyurl.com/y6v84sz8

Investors in the HER2 vaccine just can't understand why even JNJ isn't rushing to lease the vaccine for humans but now we both know why. smile

Best, Terry

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