InvestorsHub Logo

oc631

11/05/13 10:00 AM

#169360 RE: genisi #169355

The trial is sponsored by the NIAID





Gotcha

dewophile

11/06/13 9:36 AM

#169398 RE: genisi #169355

GILD examined a 6 week arm in the electron trial
SVR rates were significantly lower (this is in naives non-cirrhotics) and conclusion was that this duration is not sufficient

patients in ELECTRON with compensated cirrhosis also didnt do as well without ribavirin (in contrast to LONESTAR) with 12 weeks - and authors concluded that for these patients ribavirin or a third DAA was probably necessary.

The arms were small in size, but still..all the focus (understandably) has been on LONESTAR results, but there were some small hiccups in data for sofosbuvir as noted above that got swept under the rug

note: i posted about this previously. none of this data at AASLD is really new - the abstracts have been out for some time except for updating SVR 3 to SVR 12 data