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Re: genisi post# 169355

Wednesday, 11/06/2013 9:36:52 AM

Wednesday, November 06, 2013 9:36:52 AM

Post# of 252642
GILD examined a 6 week arm in the electron trial
SVR rates were significantly lower (this is in naives non-cirrhotics) and conclusion was that this duration is not sufficient

patients in ELECTRON with compensated cirrhosis also didnt do as well without ribavirin (in contrast to LONESTAR) with 12 weeks - and authors concluded that for these patients ribavirin or a third DAA was probably necessary.

The arms were small in size, but still..all the focus (understandably) has been on LONESTAR results, but there were some small hiccups in data for sofosbuvir as noted above that got swept under the rug

note: i posted about this previously. none of this data at AASLD is really new - the abstracts have been out for some time except for updating SVR 3 to SVR 12 data
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