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genisi

11/06/13 11:19 AM

#169412 RE: dewophile #169398

GILD 6 weeks regimens

Indeed ELECTRON study data suggested that a third DAA was necessary for a 6-weeks regimen and the NIAID study I've mentioned is testing SOF+LDV+GS-9669 or +GS-9451 instead of Riba. These regimens (I would bet more on the one with the added PI, not the non-nuke), should certainly improve SE, efficacy and durability of treatment in naive non-cirrhotic GT1 patients. No other player is testing 8 weeks regimen so for GILD even the 8 weeks is good enough especially if Riba is out.