Replies to post #132093 on Biotech Values

[genisi]

Given the amount of time 7977 has been in the clinic, no one has tried even a ex-Vivo experiment

Pharmasset looked at the drug-drug interactions with Telaprevir in vitro and concluded that antagonistic interaction is unlikely in clinical studies given the duplicity of enzymatic pathways available for delivery of the triphosphate intracellularly.

http://www.jbc.org/content/285/45/34337.full.pdf