For what it's worth, my last shipment of PAZ came from California this winter when the nights in AZ were very cold. My latest blood work showed my C-Reactive Protein shot up to 12 from 2.75. I haven't had a level that high since I started using PAZ, but then I was always picking it up directly from the headquarters in Scottsdale, Az. When I opened my last shipment the bottles were still cold, so I suspect they might has gotten very cold, or frozen in transit. Not a good sign, at least from an anecdotal view...
Liquidfan