Replies to post #4638 on Dendreon Corp fka DNDNQ

[rancherho]

The fusion gene studies also seem to be developing out of “cancer stem cell" studies and indirectly from the success of Gleevec in Phildelphia chromosome related blood cancers. There is also a free access review article in the current issue of the Journal of Clinical Investigation that gives an exhaustive history of the subject. It also suggests that these prostate cancer stem cells are not effected by hormone blockade and may be the reason why ADPC invariably progresses from ADPC to AIPC. See: Stem cells in prostate cancer initiation and progression
J. Clin. Invest. 117:2044-2050 (2007). doi:10.1172/JCI32810. http://www.jci.org/cgi/content/full/117/8/2044