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rancherho

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rancherho

Re: DewDiligence post# 4638

Thursday, 08/02/2007 12:40:43 PM

Thursday, August 02, 2007 12:40:43 PM

Post# of 12660
The fusion gene studies also seem to be developing out of “cancer stem cell" studies and indirectly from the success of Gleevec in Phildelphia chromosome related blood cancers. There is also a free access review article in the current issue of the Journal of Clinical Investigation that gives an exhaustive history of the subject. It also suggests that these prostate cancer stem cells are not effected by hormone blockade and may be the reason why ADPC invariably progresses from ADPC to AIPC. See: Stem cells in prostate cancer initiation and progression
J. Clin. Invest. 117:2044-2050 (2007). doi:10.1172/JCI32810. http://www.jci.org/cgi/content/full/117/8/2044
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