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09/21/23 3:38 PM

#633413 RE: GermanCol #633362

I also recommend you to review the new definition of GBM that doesn't include IDH mutant patients



You literally quoted the article:

65 % (n=15) had diagnoses of IDH wild type glioblastoma (WHO Grade IV)



I recommend you contact the authors of the paper who produced this Sept 12, 2023 and included IDH mutant patients among their GBM patients.

Guess Prins, Liau and Cloughesy should know better, right?

So essentially you are saying this tiny trial is obsolete and irrelevant? I agree. It's too small and too old. Maybe by 2050 they can run a P3? But this trial used a placebo and we already know Liau by her own admission doesn't know how to design a trial with a placebo, hence she threw out the control arm of the P3.