Replies to post #631339 on NorthWest Biotherapeutics Inc (NWBO)

[hope4patients]

So you’re saying Ex is a complete BS artist who routinely lies about data to disparage NWBO and DCVAX. Sounds absolutely 100% correct.

[Chiugray]

Senti, Very much appreciate your fact checking!

[supersteve13]

Ex why did you lie about this? What kind of person does this? :)

[flipper44]

Thanks. That was excellent. Bulls are getting smarter, bears are getting….. well, let’s call it disassociation.

[norisknorewards]

Some do their homework, others, well, they wing it.

[hope4patients]

This should be stickied to show what a liar Exwannabe is.

[exwannabe]

Thanks Senti! So now we know that of these patients on poly marching towards 10 years all 4 of them were grade 3 IDH mutant.

How many posts did we see here asserting the mOS in the poly arm had not been reached, when in fact we see that was reached 7 years ago.

How many posts saying the long lived patients showed a cure for GBM when in fact not a single GBM patient lived 5 years.

The data is worlds away from what was endllesly hyped here for years,

[Hopeforthefuture3]

Sure appears from this relatively small trial that dcvax needs the adjuvant polyICLC and results in great improvement. Dcvax alone as we have seen from the large trial provides modest improvement with a group of very long term survivors.
Hope it gets approved and in practice will be used with one or more adjuvant

[Hopeforthefuture3]

I have been wanting to post the factual data for sometime on the ucla study comparing dcvax (they called this placebo), to dcvax+ poly-iclc, and dcvax+resiquimod. Some here have claimed adding poly-iclc gave 50% 5 year survival.
I found Senti pretty much did most all the work already in post #631339 but I will add a bit.
There were 15 gbm patients, 4 got dcvax, 5 got dcvax+ poly-iclc, and 6 got dcvax+resiquimod
I will show the MGMT methylated with (m).
All figures are for months of OS
Dcvax - 5.5, 7.0, 14.4, 61.2(m)
Dc+poly - 24.5, 26.6, 28.6, 28.6, 52.5(m)
Dc+resiq -13.1, 16.1(m), 16.7, 19.3, 33.3, 43.3(m)
Imo addition of poly-iclc did very well but clearly not 50% 5 year survival not sure where people are getting that
MGMT - methylation clearly makes a difference
One patient of the 15 survived 5 years from the 'placebo' group
Thanks to Senti for already having all the data