Replies to post #408681 on Anavex Life Sciences Corp (AVXL)

[ALP7]

Restoring microbiome diversity

It appears that as a society were are slowly reducing the gut biome diversity of the population and there doesn't seem to be much in the way of restoring that diversity going on.

I've read that there are things that can be done to help restore microbiome diversity and possibly even more importantly, minimizing "leaky gut". Eating more fiber, fermented foods and whole foods provide the fuel for the "good bacteria" while eating processed foods loaded with things like high fructose corn syrup and all the other additives provide food for the "bad bacteria". But is there a balance that needs to be maintained?

Interesting article here, https://www.tandfonline.com/doi/full/10.1080/19490976.2018.1455790 ,that also talks about mycobiome (fungi and viruses) and also mentions that studying stool samples as is commonly done (including Anavex) has limitations:
"Care needs to be taken however as the vast majority of investigations relating to the human gut microbiota have been performed using stool samples and, as pointed out by Bajaj et alCitation19 and others, fecal communities do not reflect the gut mucosal microbiota or microbial communities at locations in the upper sections of the GI tract.Citation16"

It seems like the sentiment of 'the more we learn the more we realize how little we know' is very applicable to our knowledge of the human body.

[WolfofMia]

I agree steady also the type of fiber matters a whole lot in my opinion.

I dont buy the whole grains are good for you argument.

If you couldnt eat it as it is I would avoid it.

Rather stick to fruits, and vegetables that do not need to be cooked, is ok to but they dont need to be.

I doubt our hunter gathering friends were chewing on rice, beans, wheat, "real corn" not the fake modern version, as their teeth would have broken down, and gotten bean poisoning.

Most of these foods are relatively new to humans, we have adapted to eating them because of the technology of fire, being able to break them down and soften them.

But it has only been consuming for a few thousand years, I doubt we evolve that fast.

For now I'll let the birds and other animals enjoy them, and I'll enjoy the animals, among the other things I mentioned.

[Hoskuld]

There are places that can test your poop to see if you have pristine biome (unaffected by long-term antibiotics) rich enough for you to donate. Some places will pay you $500/day for your BMs if you qualify.