Anavex Life Sciences Corp (AVXL)

[ALP7]

Restoring microbiome diversity

It appears that as a society were are slowly reducing the gut biome diversity of the population and there doesn't seem to be much in the way of restoring that diversity going on.

I've read that there are things that can be done to help restore microbiome diversity and possibly even more importantly, minimizing "leaky gut". Eating more fiber, fermented foods and whole foods provide the fuel for the "good bacteria" while eating processed foods loaded with things like high fructose corn syrup and all the other additives provide food for the "bad bacteria". But is there a balance that needs to be maintained?

Interesting article here, https://www.tandfonline.com/doi/full/10.1080/19490976.2018.1455790 ,that also talks about mycobiome (fungi and viruses) and also mentions that studying stool samples as is commonly done (including Anavex) has limitations:
"Care needs to be taken however as the vast majority of investigations relating to the human gut microbiota have been performed using stool samples and, as pointed out by Bajaj et alCitation19 and others, fecal communities do not reflect the gut mucosal microbiota or microbial communities at locations in the upper sections of the GI tract.Citation16"

It seems like the sentiment of 'the more we learn the more we realize how little we know' is very applicable to our knowledge of the human body.