falconer--" but Missling and company know both that it does and how it"--you took the words out of my mouth--you must have "read my mind" (smile)---good post from you as usual !!!
Yes, not only is the Anavex "stuff" working, but Missling and company know both that it does and how it works. Anavex now knows the precise molecular details of exactly what happens in diseased neurons when their sigma-1 receptor ligands activate that crucial molecule.
Dr. Missling does not "know" anything more than anyone else about 2-73. He's not holding magically wonderful secrets that might get stolen away by evil greedy forces. This is not fantasyland, this is a promising young biotech trying to develop an S1 agonist therapy. That pumping is wrong.