Anavex Life Sciences Corp (AVXL)

[falconer66a]

Effective Sigma-1 Receptor Activation is the Story

Childhood Dementia--I really think this was an important event that TGD presented at--IMO the "stuff" must be working !! He knows a bit more than we do !!!

Yes, not only is the Anavex "stuff" working, but Missling and company know both that it does and how it works. Anavex now knows the precise molecular details of exactly what happens in diseased neurons when their sigma-1 receptor ligands activate that crucial molecule.

For several years Anavex has been privately experimenting with their molecules in murines (lab rodents) and other lab test animals. They know quite accurately how their molecules force neurons to function normally: by restoration of normalized autophagy (cell-keeping processes), restoration of various homeostatic processes, prompting of proper and efficient protein folding (to make functioning enzymes), facilitating gene expression (proper chromatin removal from chromosomes, to release DNA and make messenger RNA for ribosomal synthesis of proteins), and much more.

Simply, but so significantly, if the sigma-1 receptor can function normally, or the protein is adequately present, a broad spectrum of "downstream" cellular processes work normally. The key to neuron and nerve health depends on effective sigma-1 receptor function. Uniquely, the Anavex molecules make this happen.