Replies to post #365331 on Anavex Life Sciences Corp (AVXL)

[Cbdpotential]

Agreed - in fact - as the body repairs itself there will be more healthy receptors open.
Thus the importance of early intervention and prevention.

[Investor2014]

Can you name a few drugs targeting certain receptors that eventually gets rejected or repelled because the protein unlearns the chemical laws of binding?

The sigma-1 protein cannot in any way "learn" to reject or in any way repel the attachment of blarcamesine molecules

Maybe consider a bit deeper what the mechanisms of increased tolerance to a drug could be?