Anavex Life Sciences Corp (AVXL)

[falconer66a]

No, "the body" won't become "resistant" to blarcamesine.

tolerance :A condition that occurs when the body gets used to a medicine so that either more medicine is needed or different medicine is needed

Ok, understood. Thanks.

If this is a problem with blarcamesine, it means that "the body," the sigma-1 receptor protein, would no longer be activated by blarcamesine when it "gets used to it."

Not a factor here. The sigma-1 protein cannot in any way "learn" to reject or in any way repel the attachment of blarcamesine molecules. Simply, by the laws of chemical reactions and molecular physics an available blarcamesine molecule will necessarily attach to, bind to the sigma-1 protein. Thereafter, the protein is activated and all of the downstream reaction cascades and processes must necessarily follow.

Important distinction. Blarcamesine is not in any way a conventional drug. It works entirely differently. In fact, when present, nothing can stop it from working, from restoring or facilitating normal cell-keeping processes; the ones that suppress various disease states.