raja, I agree with what you posted, and what I have posted does not contradict it.
When I said "small", I meant small as in very little.
Again, I just gave a "quote" from 'ReverseRett' an authority on Rett to give a view of the size of the disease world wide for information purposes, not any thing more.
350,000 is also the number Missling mentioned as the world wide figure, and like me, he did not imply that was a target number for treatments - see the transcript.
As in the dictionary:
"Small is an adjective that describes something as little or not of large size".