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Re: RedShoulder post# 350396

Wednesday, 02/09/2022 8:13:43 PM

Wednesday, February 09, 2022 8:13:43 PM

Post# of 462513
even if he get a small percentage of the 350,000 world wide Rett patients.

It would be wise to be conservative when coming up with world-wide numbers for patients that can afford the drug. Focus should be on US/Canada and may be Europe for cost modeling.

Prices ranging 200K-500K per year are a hard-sell in places like Asia and Africa. (Regions where more than 60% -70% of the world's population lives)

For example, 200K USD = 15 million Indian Rupees (500K is 37.5 million Indian Rupees). I am pretty confident that even if some insurance plan in India covers 90% of the cost (which I highly doubt - the 90% ), almost none would be able to pay the remaining 10%. The only way out is to provide the drug at a cheaper rate - and that is not easy as no generic version will be available.
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