Replies to post #327771 on Anavex Life Sciences Corp (AVXL)

[Simonizer]

A little pre market selling pressure as SAVA drops from 70 to 50 on news Quanterix did not prepare the data charts that are under scrutiny. Hanging them out to dry.

[Investor2014]

Thorough article aligned much with Lane Simonian's Oxidative stress thesis as a main contributor to AD and I think he is right.

Also nice to see the paper focusing on Mitochondrial dysfunction as key cause of ROS with reference to Anavex A2-73.

All good adding to our DD imo.

[falconer66a]

Tells of blarcamesine cellular salubriosity.

I am waiting for you knowledgeable posters to address this technical article from Italy that Kentucky posted yesterday.

Thanks.

But there is nothing in the article to “address,” to explain, correct, or answer for. Simply, without specifically telling how it does it, the quote broadly summarizes the multitude of salubrious effects blarcamesine has on neurons. All very good outcomes; ones that few other molecules can induce for any single outcome. Astonishing, blarcamesine does a multitude of good things.

Of course, hard to explain, until the mechanism of actions of the molecule, inside cells, is sufficiently understood. In the simplest terms, blarcamesine, when binding to the sigma-1 receptor protein, “activates” it, allowing it to then properly modulate, control, or promote all of the good “downstream” reaction sequences and processes the protein controls; which, in the end, make neurons function normally; without disease or dysfunction.