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Re: None

Friday, 08/27/2021 8:56:26 AM

Friday, August 27, 2021 8:56:26 AM

Post# of 472937
I am waiting for you knowledgeable posters to address this technical article from Italy that Kentucky posted yesterday.

Quote from article.

"Interestingly, Blarcamesine or ANAVEX2-73 (NTC03790709) is a chemical compound known as an agonist of the sigma 1 receptor [164]. The therapeutic purpose of the treatment with this compound is its potential to correct a number of metabolic and synaptic abnormalities, as this receptor has been shown to restore cellular homeostasis and synaptic plasticity when activated by targeting mitochondrial dysfunction and associated OS, protein misfolding, proteostasis, and associated autophagy, and neuroinflammation [164]. The multinational trial using biomarker and precision medicine to monitor patients with mild AD or MCI is still ongoing. The same compound is also in development for Parkinson’s disease dementia."

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