Replies to post #290262 on Anavex Life Sciences Corp (AVXL)

[falconer66a]

Also, the many genotypes of HSP.

Another "rare" set of CNS diseases that blarcamesine will eventually prove to effectively treat are the many forms of Hereditary Spastic Paraplegia (HSP). Personally, I have a mild form of HSP; my legs are always stiff, from hyperexcited motor neurons in my spinal column that control the muscles in my legs. This is caused by insufficient gamma-aminobutyric acid (GABA) levels in those neurons. As shown in the girls with Rett, blarcamesine elevates, restores normalized concentrations of GABA; will be an effective treatment of HSP in most or all of its many forms.