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Re: Pineapple1 post# 290262

Monday, 12/28/2020 11:49:32 AM

Monday, December 28, 2020 11:49:32 AM

Post# of 461253
Also, the many genotypes of HSP.

Another "rare" set of CNS diseases that blarcamesine will eventually prove to effectively treat are the many forms of Hereditary Spastic Paraplegia (HSP). Personally, I have a mild form of HSP; my legs are always stiff, from hyperexcited motor neurons in my spinal column that control the muscles in my legs. This is caused by insufficient gamma-aminobutyric acid (GABA) levels in those neurons. As shown in the girls with Rett, blarcamesine elevates, restores normalized concentrations of GABA; will be an effective treatment of HSP in most or all of its many forms.
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