Replies to post #340190 on NorthWest Biotherapeutics Inc (NWBO)

[AVII77]

Now why would they take so long from “diagnosis” to randomization. And what exactly do they mean by “diagnosis” in the Weller study?

In Weller, after diagnosis, patients receive their primary chemorad. Then they are assessed for randomization into the mrd or srd cohorts.

The DCVax trial is similar. However, and it's a big however, Liau's paper reports survival from surgery. Not the randomization time point 4 months later.

ATLinsider ignores this.

[ATLnsider]

That is the point biosectinvestor, each clinical trial has its own trial protocol & its own randomization timimg schedule.

I choose not to make any imprecise or arbitrary adjustments to the official, publicly-released numbers that were reported to the FDA, uploaded to clinicaltrials.org, and published in peer-reviewed journals. This is consistent with the slide that Dr. Liau presented last week. She reported the official numbers are they were published. She made reference to any potential adjustments.

Bears wants us to make negative adjustments to the numbers, but they do not want us to make any positive adjustments to the numbers to adjust for the differences between blinded & blended data versus unblinded & unblended data.

The Bears only want to make one-way, arbitrary & imprecise negative adjustments. No positive adjustments are allowed by the Bears. As you know, the Bears want investors to get lost in the weeds & get confused. Even the Weller et. al. table that AVII77 posted, did not reflect the control group for that trial (n=374).

I trust that the FDA, the other 3 regulatory agencies, NWBio, the Prinicipal Investigators (PIs), and the 3 independent statisticians will make whatever adjustments they deem necessary.