Replies to post #283232 on Anavex Life Sciences Corp (AVXL)

[boi568]

Thank you. My stat course did not reach this point. I would do better with a scatter graph and fitted lines.

[Steady_T]

Apparently there is some missing data as the sentence at the bottom of the slide suggests. They used MCAR statistical approach to deal with that.

According to the quote below using the MCAR method increases the standard error.

There are three typical mechanisms causing missing data: missing completely at random (MCAR); missing at random (MAR); and missing not at random (MNAR) [3,4,5]. The mechanism causing missing data may depend neither on observed data nor on the missing data [4, 5]. Then data are said to be missing completely at random (MCAR) [4, 5]. MCAR causes enlarged standard errors due to the reduced sample size, but does not cause bias (‘systematic error’ that is overestimation of benefits and underestimation of harms) [4]. In this situation, the incomplete datasets are representative for the entire dataset [4

https://bmcmedresmethodol.biomedcentral.com/articles/10.1186/s12874-017-0442-1