He said, “would reduce trigs at 400 or 600” NOT “would do it without increasing LDL-C”.
That’s the big leap Du made - saying a POSA would assume no change in LDL-C above that level. Despite all other trig lower drugs working above 500 on TRIGS but raising LDL-C despite doing it while not raising or even lowering LDL-C at lower levels. She said, “No reason to think different re LDL-C.” But there was EVERY reason to think different re LDL-C!
That’s the whole point! Mori, Kurabayashi, Hayashi weren’t relevant because the test populations had moderately high trigs!!!
We have too much time on our hands here. We need to get a hobby while we wait for Singer & Co to do their jobs. Toth conceded nothing of significance in that statement.