HDG@ I thought we were talking about natural 'Fish Oil' - not 'Over the Counter' Crap Products - Come On ! ----------------------------------
Judge Du has cost (a conservative view) +7 billion for Amarin and shareholders - and you are using this type of arguments - to defend you attack on marjas's effort.
The problem in having an intelligent discussion about EPA (eicosapentenoic acid) and fish oil is the taxonomy of words. We all on this board agree that while EPA is a COMPONENT of Fish oil (along with DHA etc..), just referring to something as EPA does little to describe the vast biological difference between free EPA, Icsoapent Ethyl ester, omega 3 carboxylic acids, etc..What matters is not only the stability but the oxidative state of these EPA formulations and their bio-absorption--it makes a huge difference to the biological membrane activity of the EPA and its anti-atherogenic, anti-inflammatory, anti-oxidative vascular and endothelial protective functions. . Even Epadel(Jelis, japan ) has subtle but differing effects to Vascepa even though they are written chemically as a formula similarly. https://lipidworld.biomedcentral.com/articles/10.1186/s12944-017-0415-8 The purification extraction and handling are every bit as important as the actual chemical structure. HK